Treating Cardiovascular Disease Via Gene Therapy And The Future Direction Of This As A Therapeutic Option

2912 WordsNov 11, 201412 Pages
Topic: Discuss the technologies available for treating cardiovascular disease via gene therapy and the future direction of this as a therapeutic option. Introduction The definition of cardiovascular disease as stated by the British Heart Foundation is as follows, “cardiovascular disease includes all diseases of the heart and circulation, including coronary heart disease (i.e. angina, heart attack), heart failure, congenital heart disease, and stroke. It is also known as heart and circulatory disease.” Although there are numerous subtypes of cardiovascular disease they are all interrelated by a common setback. Atherosclerosis, which is the build-up of a fatty streak inside of the arterial walls, is the mutual element that links all forms of cardiovascular disease together. The build-up of fatty plaque inside of the artery walls can have a number of negative effects on the human body. For example, angina occurs when the narrowing of the arteries due to the build-up of plaque inhibits a sufficient amount of oxygen-rich blood to pass through to the heart. Similarly, a heart attack occurs when part of the fatty plaque breaks away or ruptures and clots the coronary arteries, drastically reducing blood-supply to the heart. Both of these conditions lead to various side effects that can significantly lower ones quality of life or even result in death. The main risk factors that increase a persons chance of obtaining cardiovascular disease include smoking, obesity, high

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