Treatment For The Time Being, There Is No Cure For Ad Essay

Patients who suffer from AD also have their memory, ability to learn and to carry out activities affected. Since, AD is not just dementia related there is also another aspect to the disease that causes “progressive neurodegeneration” (Chen). The symptoms of AD are usually slow, but they get worse over time and start to affect your daily life. The majority of people affected by AD are aged 65 and older. If a family member has AD then future generations from that family member are more likely to have AD. This is a very important disease to try to find a cure because “by 2050 as many as 115 million people worldwide will have developed dementia“ (Chen). As of right now “AD affects more than 5 million people in the U.S. alone” (Chen). This creates a huge burden on the family because it leaves their loved ones unable to function alone or to be able to do anything alone. This puts the burden on the family because then they need to find the patient a home to live in to be taken care of or they have to bring the patient in to their home and take care of the patient 24/7. People suffering from AD need to be attended to at all times of the day and constantly reminded why and what they’re doing. This affects a family because then they’re not able to do their daily routines or continue to live their normal lives. The reason is because all of their energy needs to be focused on the family member suffering form the

The FDA recently has allowed two treatments to be used for Alzheimer patients. One of the treatments is a Partial Glutamate Antagonist, which is an important transmitter to the brain. It is said that Glutamate helps patients more than sugar pills do, however; it is said that too much

Most of the seven survived families with AD member were happy with SADA services, and they confirm that their communication with this organization is satisfactory. They added that they communicate with SADA through different ways such as social media, email or phone. This make it easy for them to get faster help whenever they need it. The benefits of SADA to these families are varies as they reported, where they share their experience with AD through this association, and they discuss their different ways of how to deal with their patient depending of disease stages. Moreover, they also said that they know about update research regarding AD and its treatment, what happened in each stage, and how this disease develop and become sever through

As AD is a progressive disease with no currently known cure, all current treatments are aimed at slowing the progression of the disease; these treatments have been available since 1993 (Geldmacher et al., 2011). The desired

As per Lakhan (2017), Alzheimer's disease (AD) is a disorder dealing with neurodegeneration manifesting the cognitive and behavioral impairment that extensively affects the lives of the people who have the disease. It doesn't have a cure and deals with a long pre-clinical period as well as a progressive course. In hippocampus and some areas of

Alzheimer’s disease (AD) is a form of dementia that causes problems with memory, thinking, and behavior. AD typically involves the development of a progressive neuropsychiatric disorder that is characterized by gradual memory impairment, loss of acquired skills and emotional disturbances (Lee, Y. J., Han, S. B., Nam, S. Y., Oh, K. W., & Hong, J. T.). Every 67 seconds an individual in the United States develops AD. AD is the sixth leading cause of death in the United States. There are 5.3 million Americans diagnosed with AD (Latest Alzheimer's Facts and Figures). AD is one of the few degenerative diseases that cannot be prevented, stopped, or cured (Latest Alzheimer's Facts and Figures). Post-mortem examination of the brain of AD patients usually

Factors that are not preventable include family history, heredity, and age. Risks for eFAD include head trauma, and head to head connections. To help cope with the deteriorating disease, it is important for a nutritious diet as well as physical activity, social engagement, and mentally stimulating activities. Healthy diet helps ensure a healthy brain and heart which helps protect the body. Regular exercise is also important, this increases oxygen and blood flow which benefits cardiovascular system. Treatment for eFAD includes helping to maintain mental function and manage behavioral system. Medications that are used to comfort systems include Donepezil, Rivastigmine, and Galantamine used to treat mild to moderate Alzheimer’s. Targets for future drugs include Beta Amyloid (main components for plaque), and Tau proteins (main component in tangles.) Other hopes for drugs and therapies include the targeting of the overall inflammatory response as well as therapies to target specific areas of genetic, molecular, and cellular

In drug therapy, studies show that cholinesterase blocker can reduce psychiatric symptoms in patients with Alzheimer 's disease. Moreover, Alzheimer 's disease could cause insomnia, irritability, visual illusion, delusions and other symptoms. The drug such as hypnotics, antipsychotic drugs, antiepileptic drugs, anti-depression drugs will have good effects to those symptoms. Furthermore, study shows that neuro protective agent Namenda can block glutamate for the destruction of brain cells. Therefore, drugs that slowing down the continuing loss of life skills are currently the main treatments of moderate and severe dementia.

The patient will take prescribed medications and remain an active member of their community for as long as possible with the aid of medication and physical therapy.

The family should be informed on nonpharmacological treatments such as eating a healthy diet, exercising, socializing, and playing games where the brain is challenge. In this case the patient has been diagnosed with AD and the he would benefit from a pharmacological treatment that may delay the progression of the disease.

Another medication type that is used to help treat more severe Alzheimer’s is an N-methyl D-aspartate (NMDA) antagonist, as with Cholinesterase the treatment isn’t fully known how it works (About Alzheimer 's Disease: Treatment, n.d.; Alzheimer 's Disease Medications Fact Sheet, 2015). The antagonist is believed to help regulate glutamate concentration in the brain with the regulation of NMDA receptors, a membrane bound receptor in neurons which may be affected by a mutation in the PSN1 gene (About Alzheimer 's Disease: Treatment, n.d; Alzheimer 's Disease Medications Fact Sheet, 2015).

A disease that sweeps across the nation and affects nearly 80% of the population ages 60 and up is known as Alzheimer’s. A misconception that many people believe about Alzheimer’s is that it is a part of getting older. It is not true. Alzheimer’s is an intricate neurodegenerative disorder associated with “protein misfolding and aggregation, oxidative stress, mitochondrial abnormalities and neuroinflammatory process at a molecular level” and “synaptic loss, cholinergic dysfunction, and abnormal protein depositions in the brain”. Some symptoms associated with this disease are delusion, inability to recall or retain information, mental decline, aggression, personality changes, mood swings, and etc. Though there are currently no cures for Alzheimer’s, cholinesterase inhibitors such as donepezil, galantamine, rivastigmine and NMDA receptor antagonist memantine are used as pharmacotherapy treatment to slow down the progression and temporarily alleviate symptoms. This essay is primarily focused on Donepezil and the cognitive alleviation it results in for patients with Alzheimer’s. The first part of the paper will summarize two preclinical and two clinical trials done on Donepezil to subjects with Alzheimer’s or Alzheimers like symptoms. The second part will describe the implications and future directions from all the results obtained.

When a person is diagnosed with AD many decisions need to be made to prepare a person for the inevitable changes that will happen in the next several years. Not all of these changes need to happen at once because that can be very overwhelming to an individual, but preparedness is always a good idea. In the first stages of the disease people can lead fairly normal lives. They may experience slight memory loss and have trouble carrying out simple tasks such as handling money and paying bills, remembering special events such as birthdays, appointments, or anniversaries, and they may also experience some mood and personality changes. In the beginning stages people will need to be supervised bit not as extensively as those who are in the middle stage.

Neurodegenerative disease are characterized by the progressive loss of neurons from specific origins of the CNS .Alzheimer disease(AD) is a neurodegenerative disorder which affect brain regains that control memory and ability to learn. It is estimated that 27 million people are affected word wide and this number is expected to triple by 2050 due to increase of the population life expectancy . AD is becoming one of the most prevalent neurodegenerative conditions worldwide. Although the disease progression is becoming better understood, current medical interventions can only ameliorate some of the symptoms but cannot slow disease progression.

Dementia is a progressive process, with the symptoms and decline in function often worsening, sometimes rapidly, overtime. Although the elderly population are most frequently affected, many younger patients can also be affected. Currently, no cure, be it medical or behavioural, has been isolated, however certain treatments have proved beneficial in delaying the onset or staying off further rapid deterioration. In addition to pharmaceutical treatment modalities, other support and managerial techniques may enable n enhanced quality of life.