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Treatment Options For Opioid Addiction

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Introduction : The National Institute on Drug Abuse (NIDA) estimates that 40 to 60 percent of recovering addicts are more likely to relapse .1 Opioid addiction is defined as a pleasurable compulsive act that some may define as a disease. Unfortunately, treatment options for opioid addiction requires compliance by the patient in order to successfully overcome addiction. Probuphine is a new treatment to manage opioid addiction, which was FDA approved based on the safety and efficacy phase III clinical trial.

Discussion: Probuphine provides an answer to the continuous increase in opioid user relapsing with its very distinctive delivery platform. The subdermal implant offers a continuous drug delivery system providing non-fluctuating levels in the blood of buprenorphine for a period of six months as a single treatment.2 The most common side effects of probuphine are constipation and implant-site reactions. Due to the risk associated with insertion and removal Probuphine is only available through a Risk Evaluation and Mitigation Strategy (REMS) program.

Conclusion: Probuphine was designed to treat opioid dependence, providing a stable delivery platform. As a new and effective therapy, patients have the option of controlling the withdrawal symptoms eliminating the compliance issue.
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Introduction Extended: Opioid abuse is a disease that affects between 26.4 million and 36 million people around

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