Tuberculosis (TB) is a highly infectious disease that can harm any organ of the body, especially the lungs. Every year about over a million people die due to tuberculosis and even more are infected. A person in contact with an infected individual can easily put themselves at risks of getting TB. Due to the emergence of human immunodeficiency virus (HIV), tuberculosis infections commenced to increment more rapidly. A person with HIV has an impotent immune system which is not able to fight infections such as tuberculosis. There are many ways to diagnose, prevent and treat the further spread of this disease.
There are many ways to identify and diagnose the presence and severity of tuberculosis. One of the most prevalent ways to test for TB is
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Sputum tests may be required for testing if the chest x-ray reveals signs of TB.
Tuberculosis can spread by contagious airborne droplets that are passed on easily through close contact with a person who has active or untreated TB. As a person coughs, sneezes, or interacts, it can relinquish infectious droplets into the air. Once a person inhales the infectious droplet (bacillus), it settles in the upper airways. “Bacteria in droplets that bypass the mucociliary system and reach the alveoli are expeditiously circumvented and engulfed by alveolar macrophages, the most abundant immune effector cells present in alveolar spaces” (Knechel, 2009). These macrophages are a component of the immune system that fights to destroy the mycobacteria to obviate infection. “The outcome is essentially determined by the quality of the host bulwarks and the balance that occurs between host bulwarks and the invading mycobacteria” (Knechel, 2009). If the alveolar macrophage fails to overcome the inhaled mycobacteria, the bacteria will replicate until the macrophage lysis. As the monocytes are magnetized to the infection site, it then separates into macrophages and consumes the free bacilli. The mycobacteria then multiply within the macrophages causing it to become infected. The infected macrophages may then be transported to the lymph nodes where it can easily reach the blood stream. After two to three weeks of infection, the helper T cells are
Tuberculosis is a disease of an infectious nature caused by a bacterium known as mycobacterium tuberculosis. The disease spreads through the air. People with the disease can spread it to susceptible people through coughing, sneezing, talking or spitting. It mainly affects the lungs and other parts such as the lymph nodes and kidneys can also be affected. The symptoms for TB are fatigue, coughing, night sweats, weight loss and fever. One third of the population of the world is affected with mycobacterium tuberculosis. The rate of infection is estimated to be one person per second. About 14 million people in the world are infected with active tuberculosis. Drug resistant TB has been recorded to be a serious public health hazard in many countries. Resistant strains have developed making it difficult to treat the disease. TB has caused millions of death mainly in people living with HIV/AIDS ADDIN EN.CITE Ginsberg19981447(Ginsberg, 1998)1447144717Ginsberg, Ann M.The Tuberculosis Epidemic: Scientific Challenges and OpportunitiesPublic Health Reports (1974-)Public Health Reports (1974-)128-13611321998Association of Schools of Public Health00333549http://www.jstor.org/stable/4598234( HYPERLINK l "_ENREF_3" o "Ginsberg, 1998 #1447" Ginsberg, 1998). The World Health Organization came up with the DOTS (Directly Observed, Therapy, Short course) strategy. The approach involves diagnosing cases and treating patients with drugs for about 6-8
Tuberculosis (TB) is a very prevalent, very contagious, and very deadly disease worldwide. According to the Centers for Disease Control, one third of the population is infected with TB. (Centers for Disease Control Data and statistics) While less common than it has ever been, tuberculosis has seen an upsurge in the last three decades directly related to the AIDS epidemic, but also as a result of the development of many multi-drug-resistant strains. This is of particular concern in developing nations hit hard by AIDS infections, but it is also evidenced in an upswing in the United States. (Nester, Anderson and Roberts)
For many people in the U.S. tuberculosis represents a disease process that one rarely sees. For this reason the reality of tuberculosis outside of the U.S. can easily be lost. CDC statistics report that approximately one third of the world 's population is infected with tuberculosis.1 This can be a sobering statistic for an individual wholly removed from the idea that tuberculosis, abbreviated TB, remains a prominent disease process throughout much of the world. The objective will be to provide not just an informative description of the disease, it 's etiology, clinical manifestations, treatments, and prognosis, but also to provide a reminder that tuberculosis retains a significant presence in the world despite the early
Tuberculosis, a disease responsible for millions of deaths and has been affecting people since Aristotle’s and Hippocrates’s eras to the present day (Frith, 2014a). Tuberculosis has surged in great epidemics and then receded, Mycobacterium tuberculosis may have killed more persons than any other microbial pathogen (Frith, 2014a). Tuberculosis is an infection by the “bacterium Mycobacterium tuberculosis which invades the lungs” (Saladin, 2015) and other parts of the body. Tuberculosis is a contagious disease and when left untreated it is fatal (Kalo et al., 2015). “Although [tuberculosis] is a preventable and treatable disease…it still poses a significant threat globally” due to drug resistant strains of the disease (Kalo et al., 2015). Millions of people have contracted Tuberculosis, many now suffering from the drug resistant Tuberculosis, and millions have died from this disease (Kalo et al, 2015).
This paper contains information about the communicable disease known as tuberculosis. The “American Heritage Dictionary” defines tuberculosis as a disease of men and animals caused by microorganism that manifests itself in lesions of the lung, bones, and other parts of the body. (American Heritage Dictionary: pg. 1301). This paper contains a summary of the history of the disease, the cause of the disease, ways to prevent the disease, and the medication and treatment for the disease. This disease has been around for a long time and there is still no cure for it only treatments.
Infectious diseases can attack the human body in many forms and varieties. Tuberculosis is one type of these infectious diseases that is a bacterial infection which spreads throughout the lymph nodes and within the bloodstream enabling it to affect all organs in the human body, commonly termed TB. TB is caused by the members of the Mycobacterium tuberculosis complex. The M. tuberculosis complex includes the species M. africanum, M. bovis, M. canettii, M. microti and M. tuberculosis, these can be broken up into numerous subspecies Though, it is commonly seen in the area of the respiratory system in the lungs and those infected, (due to the bacteria in tuberculosis is able to live in inactive form), causing one who has manifested the disease to not have symptoms. (What is Tuberculosis)
“Tuberculosis (TB) remains a major global health problem. In 2012, an estimated 8.6 million people developed TB and 1.3 million died from the disease. The number of TB deaths is unacceptably large given that most are preventable,” (WHO). However, even though numbers of those infected are high, the rate of new TB cases is on the decline at roughly 2% per year. The slow decline rate is due to many things including people not being informed about the disease, and improper usage of medicines leading to drug resistant strains of TB.
Tubercle bacillus, more commonly known as Tuberculosis (TB) is an infectious disease that is contagious and airborne. TB is in many cases fatal, infectious disease caused by the strains of mycobacteria. Tuberculosis will typically infect the lungs, but is capable of spreading to other parts of the body. An infected individual can spread the infection by coughing, sneezing, laughing or otherwise transmit of respiratory fluids through the air. Tuberculosis ranks as the second leading cause of death from a single infectious agent, after the human immunodeficiency virus (HIV). In 1012, 8.6 million people fell ill with TB, including 1.1 million cases from individuals living with HIV. Within the same year, 1.3 million people died
alveoli and is engulfed by macrophages. One of the major features of M. tuberculosis is its
Tuberculosis is a contagious disease caused by a bacterial infection. Around 40% of people who have active TB disease have the infection in another part of their body. It can affect several organs of the human body, including the lymph glands, brain, spine, kidneys, or other organ, but it predominately establishes itself in the lungs where it is called Pulmonary TB. Researchers have calculated that in 2012, 8.6 million people fell ill with TB and 1.3 million died from TB. “Tuberculosis is second only to HIV as the greatest killer worldwide due to a single infectious agent”. HIV/AIDS is the leading cause of tuberculosis cases around the world. Overall, one-third of the world's population is currently infected with the TB bacillus.
Infectious diseases remain among the leading diseases in the world. Illness and death from infectious diseases are particularly tragic because they might be preventable and treatable. Tuberculosis is one of the most serious infectious diseases. People almost forgot about this disease and think that does not exist around us. Tuberculosis is a very prevalent, contagious and deadly disease worldwide. According to World Health Organization (WHO) (2014), “Today, tuberculosis remains one of the leading infectious disease killers around the world. Emerging drug-resistant strains are presenting a new challenge in the ever-changing battle to control and prevent
Tuberculosis is an infectious disease caused by a bacterium called Mycobacterium tuberculosis (Marieb, 2012). Tuberculosis is a contagious infection that begins in the lungs and spread to other organs in the body including the kidneys, brain and bones. Tuberculosis is spread by inhaling airborne droplets from an infected person. These airborne particles are spread when the infected person sneezes, coughs or laughs. Tuberculosis cannot be spread, by contact. Tuberculosis is caused by a rod shaped bacterium or bacillus called Mycobacterium tuberculosis. These droplets are discharged into the air by a person with active tuberculosis (Britannica, 2012). The spreading progress is very effective. These droplets can remain in the air for several hours in addition it only needs ten bacilli to start an infection. When the infected air is breathed in, the bacilli enter the lungs through the bronchioles and into the alveoli. The bacilli then infect the alveoli
Tuberculosis is a prime leading health problem throughout the universe. It is the second utmost cause of death from a contagious agent killing nearly 20 million people each year. There are two major elements that are contributing to the current TB endemic and its combined morbidity and mortality include; growing human immunodeficiency virus outbreaks and rising prevalence of resistance of Mycobacterium tuberculosis strains of the most effective anti-TB drugs. Another causative to the development of resistance is the destitute quality of drugs, improper treatment management, patient non-cooperation and malabsorption due to other integral conditions. This paper is comprised of the pathophysiology of TB, etiology, diagnosis, signs and
Pulmonary tuberculosis is characterized by classical general symptoms such as night sweats, cough, coughing up with bloody sputum, weight loss, loss of appetite, weakness, inflammation of lymph nodes, fever, pneumonitis and chest pain (Davis, 2016). Mycobacterium leprae is an another common type of bacteria, which causes leprosy by showing symptoms of skin discoloration skin lesions skin nodules skin plaques thickened skin nasal congestion nosebleeds (Davis, 2016). Extra pulmonary tuberculosis have symptoms varies according to localized part of body get infected.Skeletal and arthritis TB (also termed Pott 's disease) shows spinal pain, back stiffness, pain in knees and hip joints while genitourinary TB includes dysuria, flank pain, Gastrointestinal TB shows difficulty in swallowing, nonhealing ulcers, abdominal ache, malabsorption, bloody diarrhea (may be bloody) while Miliary TB and Pleural TB shows many small nodules widespread in organs, empyema and pleural effusions (Davis 2016). Humans are sometimes susceptible to Mycobacterium bovis (M.bovis). Pulmonary Tuberculosis affects directly to lungs and occur most often in young kids who has weaken immune system by showing symptoms with a productive cough more than three weeks with high fever and chest pain which can easily spread to others as bacteria are growing rapidly while Extrapulmonary Tuberculosis does not affect to the lungs. (“Tuberculosis
Tuberculosis has been an influential part of global history, causing negative affects worldwide. In fact, tuberculosis caused about 1.3 million deaths in 2012 (Center for Disease Control and Prevention, 2014). This re-emerging infectious disease is relevant to the function and development of the global economy and healthcare system. When learning about the physiology of Mycobacterium tuberculosis and its effects on the human body, one can understand the hardships of current epidemics and the call that we as citizens of this world have to help those who are vulnerable to tuberculosis.