Tuberculosis Current Event

Tuberculosis is most of the feared and widespread that has harassed humans. Tuberculosis is a disease that affects the lungs and other organs too. This is a very serious disease that can cause death and the worse part is that this disease travels to one person to another. In the book, Know about Tuberculosis, a boy who has tuberculosis sneezed on another boy named Kevin who did not automatically catch tuberculosis, but the terms have taken root. According to the book, Know about Tuberculosis, “In the United States, about ten to fifteen million people are infected with this disease, but only ten percent of people are infected; however doctors assume that the battle against tuberculosis is increasing around the world.” Tuberculosis is among the major concerns for the World Health Organization due to its contagious nature.

Tuberculosis is a deadly disease that is now affecting our world and the people living in it in a horrible way. Due to many factors such as poverty, HIV/AIDS, and lack of health care, many third world and developing countries have been left very vulnerable to tuberculosis. It is affecting a large part of these countries and is leading them deeper into poverty and sickness. The effort to help these countries against tuberculosis has only been slightly effective against this widespread and destructive disease.

Once believed to be easily treated and prevented, Tuberculosis (TB) has recently been making a steady comeback. Previous to modern medicine, TB claimed millions of victims, spreading from person to person like wildfire. Around the 17th-18th centuries, the “White Plague” took the lives of 1 in 5 adults (20%) in Europe and North America (Iseman, 1994). However, as technological advances progressed, this seemingly ferocious viral disease became a primal, insignificant thing of the past. But, in the nature of all bacteria, TB has, in the recent years, mutated to become progressively drug resistant. Why is Tuberculosis coming back with a vengeance? Well, the answer’s quite simple. TB has done an amazing job of standing in the corner and

Tuberculosis, the white plague as used to be called once upon a time is still one of the deadliest bacterial killers affecting almost all parts, all corners of the globe. Though successful anti-tubercular antibiotic regimens and effective vaccine are available for decades and being used in the battle against Koch’s bacillus, Mycobacterium tuberculosis, the causative agent of this chronic multi organ granulomatous disease, our strand in the battle continuously seems to be in the losing side. Moreover the increasing prevalence of HIV-AIDS and diabetes mellitus is being proved to be providing predisposition to tuberculosis. As witnessed by the WHO, which has estimated that, in the year 2012, 8.6 million people have developed tuberculosis and 1.3 million have died of the disease including 320000 deaths of HIV-TB co-infected people (Global tuberculosis report 2013. World Health Organization; 2013). Long term antibiotic therapy and that too associated with several side effects and discomforts have diminished patient compliance with the anti-tubercular chemotherapy. This fact in turn has raised the new deadlier MDR-TB and XDR-TB strains. The whole scenario is a matter of panic and questioning the effectiveness of anti-tubercular antibiotics, immunologic efficacy of century old BCG vaccine and all other medical advents.

According to the World Health Organization, tuberculosis (TB) is the number two killer worldwide due to a single infectious agent (WHO, 2017). In 2015, 10.4 million new cases have been identified and 1.8 million people have died from this disease (WHO, 2017). TB is caused by the bacteria Mycobacterium TB, and the majority of TB deaths occur in low and middle-income countries. This disease is curable and preventable, but the lack of access to proper healthcare and medication administration makes it a concern for the most of the world’s population. TB is an airborne disease that can transmit when an infected person coughs, sneezes, spits, laughs, or talks. The majority of TB cases can be cured when the right medications are available and

Often times, people in third world countries face health problems that are not experienced in first and second world countries. Diseases that do not exist in the countries such as the US anymore are still some of the leading problems in poor nations. Professor Susan Craddock from the department of Gender, Woman and Sexuality studies gave a presentation that focused on Tuberculosis, which is falls into a category of diseases called “neglected diseases”. They are called neglected because the development of vaccines and drugs to cure the diseases has decreased to about nothing. The market for these drugs is not lucrative enough for pharmaceutical companies in higher income countries to invest in research. Since the low income countries do not have the resources to carry out research for these drugs the number of neglected disease-related deaths has increased. I found the presentation interesting and enlightening especially because I am interested in the pharmaceutical field. In response to the neglected diseases, different organizations have come together to research and develop vaccines and drugs that can treat these diseases.

Pulmonary tuberculosis is an illness of the elderly, the poor, the alcoholic, and, today, the drug addict. TB, an indication of the frightening mortality of tuberculosis is contained in a report written about New York City in 1826. At that time New York had a population of 166,086. The total number of deaths in the two years preceding the report was 9,359, of which 1,579 were due to "consumption." This means TB accounted for 17% of deaths due to all causes.

The author is stating in this article that society is becoming more concerned towards worldwide epidemics. The writer brings to our attention and talks over the effects of tuberculosis and how they are using giant pouched rats as a secondary source in detecting TB quicker and more reliable than x-rays. The human nature of society currently is turning out to be more compassionate and kindly towards others; at this moment civilization thrives on creating a broader impact to stop diseases that cause chaos in the world today.

Several studies of combination drugs are being conducted or are being planned, although these trials face barriers that include pharmacokinetic interactions, the reliance on clinical rather than surrogate end points, and the relatively low financial incentive for drug companies to perform

Without taking proper and correct treatment, mortality rate cause by tuberculosis in Canada will be two-thirds of the population.

Throughout history humans have been plagued with mycobacterial diseases, most notably, Tuberculosis and Leprosy, caused by Mycobacterium tuberculosis and Mycobacterium leprae, respectively. [1] However, with the advent of antimicrobial cocktails and public health measures, the incidence of these diseases saw a sharp decline. [1-2] Conversely, with the increase of pulmonary diseases due to smoking, immunosuppressive drug therapies, and the HIV/AID epidemic, the incidence of diseases caused by non-Tuberculosis Mycobacteria (NTM) began to increase. [2] These NTMs are ubiquitous in nature and can be found nearly everywhere (e.g., soil, domestic and wild animals, tap water, surface water, milk, and food.) [3-4] Currently, just

Mycobacterium tuberculosis (MTB) is an infection that about one-third of the population has. MTB, which is an airborne infection, can infect nearly any organ of the body. Human immunodeficiency virus or HIV also has an impact on the world. In 2011, it was estimated that around 34 million people were living with HIV. This virus is contracted by the exchange of blood or bodily fluids whether it be from sexual contact or sharing needles or syringes used for drugs. In addition, HIV is a retrovirus specifically attacking the CD4 T lymphocytes. Acquired immunodeficiency syndrome (AIDS) is the disease caused by already having the HIV infection. The possibility of having both diseases has gradually diminished due to the improvements made in

When I was 12, my mother underwent a knee replacement. Five years later, my father was diagnosed with leukemia and received chemotherapy. I witnessed first hand my parents’ frustrations in maneuvering the healthcare system because they did not speak English. Not only did I act as their translator in navigating the medical terminology, diagnosis, treatments, and billing but in doing so, it encouraged me to better understand why patients with language barriers, such as my parents, felt disregarded and received substandard care. During my freshman year at the University of California, Los Angeles (UCLA) I put into perspective the lack of educational opportunities in underserved communities and their contributions to health disparities. I have felt that it is my calling to address the lack of access to education, health care and

Table 1 shows the antimicrobial resistance pattern for all antimicrobials agents used, and the MIC for rifampicin. Table 2 shows the relative quantification of the transcript levels for five rpfs in M. tuberculosis isolates, exposed to sub-MIC (MIC=128 mg/L) concentration of RIF.

India, the second most populous country with over 1.31 billion people, has the highest burden of tuberculosis (TB) in the world, accounting for 20% of the global incidence of TB, and an even higher share of global incidence of multi–drug resistant (MDR) TB. With an estimated 2 million new cases of TB and 5, 00,000 TB-related deaths in India annually, those who got diagnosed with different forms of DR-TB were 35,385 cases but only 20,753 people started on multidrug-resistant TB (MDR-TB) treatment in 2013. The National Tuberculosis Program was launched in 1962, but suffered heavily continuing TB led mortality. Acknowledging this reality, a Revised National Tuberculosis Control Programme (RNTCP) was launched by the Government of India in 1997, however even today it does not comply with World Health Organization (WHO) recommendations.