Two Biological Explanations of Schizophrenia Essay

Likewise we can not say for sure that a Schizoprenogenic mother isn’t the result of having a schizophrenic child and not the cause of schizophrenia in the child. Both the psychological and biological explanation of schizophrenia are criticised for being too simplistic an explanation of the causes of schizophrenia. However, both theories are not rigid in their views and most scientists believe that is a complex interaction between biological and environmental factors which determine the development of schizophrenia. Although most supporters of the genetic explanation believe that there is a genetic predisposition to schizophrenia and therefore accept other psychological and environmental factors.

In an attempt to gain a position as a psychologist, I will be discussing schizophrenia and the disorder’s casual factors, associated symptoms, the areas of the brain it affects, and the neural basis of the disorder. I will continue on to discuss appropriate drug therapies. In addition I will also be reviewing two separate case studies, each on a different disorder. I will be examining each problem from the perspective of a bio psychologist. I will define the patient’s diagnosis at length I will relate each case to the nature-nurture theory, and talk about any helpful drug interventions or solutions for each disorder. When talking about drug intervention, it is also important to discuss the positive and

Schizophrenia is classified as a mental disorder that shows profound disruption of cognition and emotion which affects a person’s language, perception, thought and sense of self. The dopamine hypothesis states that schizophrenic’s neurones transmitting dopamine release the neurotransmitter too easily, leading to the characteristic symptoms of schizophrenia. This hypothesis claims that schizophrenics have abnormally high amounts of D2 receptors; receptors that receive dopamine, therefore resulting in a higher amount of D2 receptors binding to the receptors causing more impulses. Dopamine neurotransmitters play a

Schizophrenia is a unique disease in its pathophysiology. For their early lives, patients appear healthy. However, symptoms begin to appear during adolescence or early adulthood and may be triggered by changes in the brain during puberty. The first signs of the illness include anxiety, depression, changes in friends, sleep problems, irritability, dropping grades, and having trouble concentrating (Picchioni and Murray, 2007; National Institute of Mental Health (NIMH)). Delusions and hallucinations typically begin between the ages of 16 and 30 (NIMH).

Genetics play a role in the development of schizophrenia. When looking closer at the brain chemistry between a person with schizophrenia and a person with out schizophrenia there are

Expert’s reason that unevenness in the complicated interconnected chemical responses of the brain connecting the neurotransmitters dopamine and glutamate, and maybe others, performs a part in schizophrenia. Neurotransmitters are elements that permit brain cells to interconnect with each other. Experts are acquiring more about brain chemistry and its connection to schizophrenia. Similarly, in small methods the brains of people with schizophrenia appear diverse than those of healthful people. For instance, fluid-filled holes at the middle of the brain, called ventricles, are greater in certain people with schizophrenia. The brains of people with the disorder similarly manage to have less grey matter, and certain

There are two main biological theories which explain the assumed causes of schizophrenia: Genetic and Dopamine Hypothesis.

Genetics can cause differences in brain chemistry and biochemistry may be important in the development and maintenance of schizophrenia. The dopamine

Research by Johnstone in 1994, explained the biological approach of interventions, explanation and treating of schizophrenia patients (Hansell & Damour, 2005). In studies of Fisher in 2001, discoveries that the brain had more dopamine receptors know as B_2 receptors in a person suffering from schizophrenia, than a non-suffer (Hansell & Damour, 2005). Biological findings of schizophrenia suggest that a genetic factor was hereditary, but not conclusive because the element of environment does make a difference (Hansell & Damour, 2005).

Schizophrenia is a psychotic disorder characterized by distorted thinking, impaired emotional responses, poor interpersonal skills and a distortion of reality. It is the most common of psychotic disorders that, in most countries around the world, affects around 1 per cent of the population. In terms of explanations for the disorder, two central types of explanations arise – psychological explanations and biological explanations. Whereas psychological explanations tend to focus on cognitive, emotional and environmental factors that may cause the disorder, biological explanations tend to focus on genetic, biochemical and neuro-anatomical factors as the cause of the

According to James G. Hollandworth of the University of Southern Mississippi, schizophrenia is primarily characterized by a disintegration of reality perception, consciousness, and thought process which results in a debilitated proficiency in social and professional faculties (Hollandworth, 1990). While schizophrenia can most arguably be classified as a predominantly genetic affliction, there are others factors which can contribute to its development even without a genetic predisposition. These elements include birth defects such as hypoxia and low birth rate, neuroanatomical anomalies, viral infections, along with low IQ and cerebral atrophy (Hollandsworth, 1990). While these components in themselves are not sufficient enough to cause the disorder, they result in an increased risk for developing the disease. One theory for the cause of schizophrenia that has been studied with great validity is the dopamine hypothesis. This theory postulates that schizophrenia is caused by an overabundance of the dopamine-dependent areas of the brain causing an imbalance that affects the entire system (Hollandsworth, 1990). For this reason many of today’s schizophrenia treatment drugs inhibit dopamine receptor activity in an attempt to return it to its natural equilibrium. Although even with advances in modern science and new drugs being developed every day, the illness is still only treatable and its symptoms still emerge even

Experts think that schizophrenia is caused by many contributing factors according to the NIMH and Berstein. Although there is a lot about schizophrenia that experts may not know, they do know that it is a genetic disease hat runs in families. According to the NIMH, those affected individuals are highly likely to have a close relative such as a mother, father, sibling, or grandparent with the disorder. According to Tischauser, a person with one parent who has the disease is ten times more likely to develop schizophrenia than a member of the general public. Thirty-nine percent of people who have both parents afflicted with the disease also develop schizophrenia. Schizophrenia majorly affects a person’s brain. The disorder disrupts the way that the brain cells function and communicate with each other. In the affected persons’ brain, the neurotransmitters that carry signals from one cell in the brain to the other may be abnormal or the transmitter may be malfunctioning (Bernstein). It is believed that several genes are associated with an increased risk of having schizophrenia. No single gene causes schizophrenia by itself. In fact, the genetic differences may include up to hundreds of different genes and the disruption of brain development. Bernstein states that we do know that there is an affected gene that is key to making important chemicals for the brain. Also, experts say that the environment is a factor in people with schizophrenia. For example, some environmental factors may include exposure to viruses, malnutrition before birth, problems during birth and other not yet known psychological factors. According to Anushree Bose, other factors that contribute to having schizophrenia include an imbalance of brain chemistry and different structures of the brain (7). The NIMH also adds that a person’s brain who has schizophrenia will look similar to a healthy person’s brain, but only in small ways. They

Biological, psychological, and sociocultural viewpoints have been developed in an attempt to explain schizophrenia. All three viewpoints point out various factors that may contribute to the development of the disorder.

The Dopamine Hypothesis theorizes that the symptoms portrayed in Schizophrenia is can be explained by abnormal function of dopamine in the brain. There have been three versions of the Dopamine Hypothesis. The first version of the hypothesis focuses on the dopamine receptors. Antipsychotic drugs that impact the metabolization and reabsorption of dopamine where found to be effective in treating the symptoms. It was theorized that if the symptoms of a Schizophrenic episode can be treated by the use of dopamine

1978 shields discussed 11 studies of the identical and non-identical co-twins of over 1300 schizophrenics from seven countries and then of these comparisons showed a higher concordance rate among identical twins. (A, C, Smith 1982 p.g 93) Research is still going on today to find out more about how genes and life events influence who gets schizophrenia.