Type 1 Diabetes : An Autoimmune Disease

Type 1 diabetes is also called insulin-dependent because the pancreas produce little to no insulin due to the destruction of beta cell in pancreas(Bardsley et al, 2004). Therefore, the insulin have to be injected manually for body to function normally. (Seewaldt et.al, 2000) states that in type 1 diabetes, the beta cell located in the islets of Langerhans have antigen that cause the immune system to produce antibodies and kill the insulin producing cells. The autoimmune response is thought to be caused by the autoreactive CD4 and CD8 effector cells that recognise islet self-antigens, as an outcome there is greater than 90% destruction on insulin producing cell BACH (1994). Similarly, (Nakayama et al,2005) and (Kent et al, 2005) supports that insulin in itself is a

Type 1 Diabetes, also called “insulin-dependent diabetes”, “juvenile diabetes”, or “early-onset diabetes”, is when the pancreas produces little to no insulin. Type 1 diabetes is not as common as type 2, but 10% of all diabetics are type 1. Patients with type 1 diabetes will need to take insulin injections for the rest of there lives. Also people with type 1

Diabetes type 1 develops when the immune system attacks the only cells that create insulin, the pancreatic beta cells. Due to the cells being destroyed, the person with diabetes type 1 has to be

Type 1 diabetes forms when the insulin forming cells in the pancreas are destroyed. Normally, the glucose you obtain from your food stimulates the pancreas to release insulin into into the blood. This insulin is used to help secrete and transport the glucose molecules

There are many types of diabetes. The two I will be discussing are type 1 and type 2. Type 1 generally affects young people and requires treatment with insulin. Five to ten percent of Americans with diabetes have this type. People with type 1 diabetes do not produce insulin and need regular shots of it to keep their blood glucose levels normal. People who are at risk for type 1 are those who have a family history of the disease,

Type 1 diabetes, previously called juvenile diabetes, is an incurable condition that is normally diagnosed in children and young adults. Type one diabetes (T1D) is an autoimmune disease with an unknown cause. Symptoms can be subtle and if gone undiagnosed and untreated, T1D can be fatal. The treatment of T1D requires daily injections of insulin to break down excess sugar in the blood. Treatment costs of diabetes are high and the complications associated with T1D only increases those costs. Historically people with a diagnosis of type 1 diabetes (T1D) did not have long life expectancy. Today with advancements in treatment, commitment to managing insulin levels and living a healthy life style, T1D patients can lead a long an full life.

Type one diabetes is an autoimmune disease. When a person has type one diabetes the immune system attacks the beta cells that produce insulin. When enough cells are destroyed the body doesn’t produce enough, or any insulin. Without insulin your cells do not absorb the glucose that accumulates in the blood stream. In addition to a spike in the blood sugar, the body is not storing the glucose as glycogen as a reserve.

Type 1 diabetes is usually a progressive autoimmune disease, in which the beta cells that produce insulin are slowly destroyed by the body's own immune system. It is unknown what first starts this cascade of immune events, but evidence suggests that both a genetic predisposition and environmental factors, such as a viral infection, are involved.

In recent studies, Diabetes type 1 has been scientifically linked to a chronic autoimmune disorder. The immune system attacks the beta cells, in the Islets of Langerham, located in the pancreas. This leads to the insulin producing cells to be destroyed and damaged, which ultimately ends up with very limited blood glucose or no insulin production at all.

Type one diabetes is when the pancreas is not able to produce enough insulin for the body to function effectively, and a person becomes insulin dependent. It usually happens in children and young adults and is not as common as type two with “10 to 15 percent of all people with diabetes having type one.” (Diabetes Australia, Victoria 2008). Type one diabetes is an “autoimmune disease” (Diabetes Australia, Victoria 2008) where the pancreas cannot produce enough insulin

The disease type one diabetes happens when the human immune system destroys the beta cells that are in our pancreas. The beta cells are responsible for making the insulin in our pancreas. Insulin is a hormone in our body that works like a key does in a door. Insulin unlocks our cells to let sugar into our cells from our blood stream. Our body then can utilize the sugar for energy. People that have the disease type one diabetes have very little insulin because their beta cells in their pancreas have been destroyed. People that have the disease type one diabetes have high levels of sugar in their blood because the sugar cannot get into their cells.

Type 1 Diabetes occurs when the body is unable to produce insulin, a hormone that's needed to control the amount of sugar, or “glucose” in your blood. For example, when you eat, your digestive system breaks down food and passes its nutrients, which includes glucose, into the bloodstream.

Type 1 diabetes, also referred to as Insulin Dependent Diabetes Mellitus (IDDM) or Juvenile Diabetes, can be caused by a genetic disorder. It can occur at any age, but it is most often diagnosed in children, adolescents, or young adults around 20 years old or before a person is 30 years of age. Insulin is a hormone produced by special cells, called the beta cells, in the pancreas, an organ located in the area behind the stomach. Insulin is needed to move blood sugar (glucose) into cells, where it is stored and later used for energy. In type 1 diabetes, these cells produce little or no insulin. Without enough insulin, glucose builds up in the bloodstream instead of going into the cells. The body is unable to

Type 1 diabetes formerly known as insulin dependent or juvenile diabetes is a sudden onset in which the body produces little or no insulin and commonly begins in childhood or adolescence, although anyone can develop type 1 diabetes at any time (Gale, 2013). Without insulin, sugar stays in the bloodstream and cannot be used to fuel the body cells. In this disease the body 's immune system attacks and destroys beta cells in the pancreas by producing autoantibodies that cannot distinguish between an intruder and the bodys own beta cells that produce insulin (Brill, 2008). Thus, people with type 1 diabetes must take insulin injections to stay alive as the disease can be rapidly fatal without daily administration of unsulin (WHO, 2008).

The cause for type 1 diabetes is not well known but genes may play a role in this type of diabetes. Another suspicion for the cause of type 1 diabetes is the environment, for example a virus. A virus may cause the immune system to attack the cells in the pancreas because it detects a foreign organism. According to WebMD (2016) autoantibodies are present in almost all patients with type 1 diabetes.