Type 1 Diabetes History

Type 1 diabetes is also called insulin-dependent because the pancreas produce little to no insulin due to the destruction of beta cell in pancreas(Bardsley et al, 2004). Therefore, the insulin have to be injected manually for body to function normally. (Seewaldt et.al, 2000) states that in type 1 diabetes, the beta cell located in the islets of Langerhans have antigen that cause the immune system to produce antibodies and kill the insulin producing cells. The autoimmune response is thought to be caused by the autoreactive CD4 and CD8 effector cells that recognise islet self-antigens, as an outcome there is greater than 90% destruction on insulin producing cell BACH (1994). Similarly, (Nakayama et al,2005) and (Kent et al, 2005) supports that insulin in itself is a

For unknown reasons, the body of a T1D attacks the insulin producing cells, called islets, that are formed in the pancreas and destroys them. This type of attack is known as an autoimmune disorder (Diabetes Research Institute Foundation [DRIF], n.d.). Insulin is the hormone that allows sugar to enter cells, and produce energy. The body now sees islet cells as foreign and eventually the pancreas yields little to no islet cells. Once there are no more islet cells to produce the insulin hormone the sugar levels in the blood become high, called hyperglycemia. This disturbance in homeostasis is not like type 2 diabetes (T2D), where the body becomes insulin resistant. In a T2D, the pancreas still produces islet cells and they are still

Diabetes is a disease that can be devastating to some families, but it is not that bad as it seems. With the correct amount of exercise and moderation, it can be maintained with several different methods. A large part of the United States population has a form of diabetes. Today, there are many treatments that improve the lives of those living with this disease. With the correct understanding, it can be manageable and change the lives of the diabetic and his/her family. Some people may think of this as a bad thing for children to have but with the proper management and exercise, it can be maintained as well as bring a family closer to one another. As a brother of a type 1 diabetic, I know how hard it is to live with it and how to

This disease does not favor one gender over the other, it effects males and females equally. Currently, the origin of diabetes is a conundrum. Although, it is understood that the immune system attacks the beta cells but it is not clear how or why it occurs. It is hypothesized that T1D maybe hereditary and environmental factors contribute to the onset (5). Symptoms prevail in individuals whom have the majority of their beta cells destroyed via a cellular mediated autoimmune response (1).

As of yet, the origins of diabetes are still unknown, however, for type 1 diabetes,

Type one diabetes is an autoimmune disease. When a person has type one diabetes the immune system attacks the beta cells that produce insulin. When enough cells are destroyed the body doesn’t produce enough, or any insulin. Without insulin your cells do not absorb the glucose that accumulates in the blood stream. In addition to a spike in the blood sugar, the body is not storing the glucose as glycogen as a reserve.

Being diagnosed with type one diabetes it creates multiple situations that requires the patient to take responsibility to help control their disease. While also the diagnoses can restrict the opportunities for the patient. According to the American Diabetes Association, “In 2012, 29.1 million Americans, or 9.3% of the population, had diabetes. Approximately 1.25 million American children and adults have type 1 diabetes” (ADA. Par.1). Thus being diagnosed by type one

Type 1 diabetes is usually a progressive autoimmune disease, in which the beta cells that produce insulin are slowly destroyed by the body's own immune system. It is unknown what first starts this cascade of immune events, but evidence suggests that both a genetic predisposition and environmental factors, such as a viral infection, are involved.

In recent studies, Diabetes type 1 has been scientifically linked to a chronic autoimmune disorder. The immune system attacks the beta cells, in the Islets of Langerham, located in the pancreas. This leads to the insulin producing cells to be destroyed and damaged, which ultimately ends up with very limited blood glucose or no insulin production at all.

Type I Diabetes was once referred to as Juvenile Diabetes or Insulin Dependent type Diabetes Mellitus (IDDM). Type 1 diabetes, is an incurable but treatable disease which can occur at any age but is mostly found in children. Couch et al. (2008) states, “Juvenile diabetes affects about 1 in every 400-600 children and more than 13,000 are diagnosed yearly” (pg. 1). A 2014 CDC fact sheet concerning diabetes, showed that, “In adults, type 1 diabetes accounts for approximately 5% of all diagnosed cases of diabetes in the United States.” It seems that we all know someone who is affected by diabetes; either type 1 or type 2. Diabetes seems to be such a common-place illness and is much more prevalent in today’s society. However, this hasn’t always been the case. Gale (2002), states, “At the start of the 20th century, childhood diabetes was rare… (pg. 3353).” In this paper, I will provide information about Juvenile or Type I diabetes in order to educate the reader about this illness.

Type 1 diabetes ‘usually develops in childhood or adolescence’ (WHO 2011, p. 2), and will result in death if the disease is not treated by consistent insulin injection. This type of diabetes is slightly more complex as it is substantially caused by gene mutation (WHO 2011, p. 2). The World Health Organization (2011, p. 2), describes the aetiology of the disease as the ‘autoimmune destruction of the beta cells of the pancreas.’

Type 1 diabetes is a life long auto-immune condition where the immune system is activated to destroy the cells in the pancreas that produce insulin. Scientists are not sure what causes this auto-immune reaction (Vanstone et al. 2015). It can occur at any age, although it is most often diagnosed in children, adolescents or young adults. The immune system incorrectly sees the insulin-producing cells in the pancreas as foreign, therefore it destroys them. The role of these insulin-producing cells is to sense glucose in the blood, and in response produce the essential amount of insulin to regulate the blood sugar (Griffiths & Payne 2014 pp. 390-391). Insulin’s role is to get glucose from the bloodstream into the body’s cells. Without insulin,

This informative article I am writing is about type 1 diabetes. I chose this disease as I know a lot about juvenile diabetes as I was diagnosed with it when I just turned four years old. While diabetes is very serious and can kill you if it is not managed, it is a disease that you can live with for a long time if you take care of yourself. Type 1 diabetes is an autoimmune disease that can attack both children and adults. Autoimmune means your body attacks itself.

Diabetes Type 1 is a severe chronic disease, which arises from the lack of insulin caused by the destruction of insulin producing beta cells of the pancreas. It is an autoimmune disease that attacks and destroys beta cells. In a healthy body, the immune system works as a guard, protecting our body from various foreign substances, such as viruses and bacteria, although in case of type 1 diabetes immune system destroys body’s own cells. (CITE)

Type 1 diabetes is an autoimmune disease that begins when the pancreas quits making insulin. Insulin plays a key role by letting glucose enter the body’s cells, and then uses it for energy. When the body doesn’t get the