Type 1 Diabetes Mellitus And Mellitus

1711 Words7 Pages
Introduction: Type 1 Diabetes Mellitus is a disease that occurs when insulin-producing beta cells of the pancreas are damaged or are being destroyed (Mahan, Escott-Stump & Raymond, 2012). The gradual destruction of the beta cells of the pancreas usually leads to complete insulin deficiency, which ultimately manifests itself in the following symptoms at clinical onset: “high blood glucose (hyperglycemia), frequent urination (polyuria), excessive thirst (polydipsia), and a significant amount of weight loss, dehydration, electrolyte disturbances and ketoacidosis”, requiring dependency of exogenous insulin in order to promote optimal glycemic control in order to prevent further more severe complications; such as, ketoacidosis, microvascular diseases, macrovascular diseases, neuropathy, or worse – Death (Mahan et al., 2012). Type 1 Diabetes Mellitus can result from two existing forms: 1. Immune-mediated diabetes Mellitus, which is characterized by autoimmune destruction of the beta cells of the pancreas and an idiopathic (unknown cause) commonly seen in ethnic groups of African or Asian descent (Mahan et al., 2012). Of all diagnosed diabetes cases, prevalence of Type 1 Diabetes Mellitus cases account for 5%-10%, and although onset may present itself at any age, 70% of cases are diagnosed in young adults (younger than age 30), with a peak in occurring incidences seen mostly in children and adolescents (Mahan et al., 2012). “In the United States, approximately 1 in every 400
Open Document