Type 1 Diabetic Summary

Do you ever wonder where Diabetes comes from or where it originated from? Well that’s exactly what we’re going to discussing today.

The individual I chose to observe is my cousin who is a 24-year-old male who was diagnosed with type1 diabetes since the age of 14. But before being diagnosed with type1 diabetes my cousin was healthy teenager that would eat just like any other teenager, but his life drastically change right away after being diagnosed with type1 diabetes. He now suffers from weight lost, nausea, body pain, and is insulin dependent. Being insulin dependent was one of the biggest changes in his life, because he had no idea what was occurring to his body and was not inform about diabetes. It took a while for my cousin to get used to the changes that were occurring to him as a teenager, but now that he is older and cautious about his disability, he lives a healthy

cells which can help treat people suffering from diabetes. Even tissues can be grown again by

Diabetes one, and two revolve around the hormone insulin. Insulin is produced by the pancreas and its job is to help the cells in the body absorb glucose from the blood. Once the glucose is absorbed it signals beta cells from the pancreas to secrete insulin. Insulin enables glucose to enter cells of the liver and muscle. After the glucose has entered the cells, hormones that include insulin, decided if the glucose will be used as energy, or stored as glycogen for the future. The stored glycogen is important because if you haven’t eaten and your blood sugar is low, the body can take from the stored glycogen and use it as a source of energy.

There are two types of diabetes. Type 1 diabetes is a condition in which the pancreas does not produce enough insulin, due to the destruction of beta cells. This results in chronic hypoglycemia. Type 2 diabetes is correlated with obesity and unhealthy lifestyle behaviors. The body is resistant to insulin because the skeletal muscle is unable to respond to the insulin-mediated glucose uptake.

stem cells were discovered a long ago that they can be beneficial for fighting against the killer diseases but after passing of two decades of the discovery it has been profound that (hESCs) are being tried as a treatment for two noteworthy illnesses: heart fail and type 1 diabetes.

Type one diabetes is a disease which cannot be curable. Though it can be controlled by medication, healthy foods and exercise. Diabetes is when the body is not making enough insulin to keep the blood sugar levels normal. The sugar in the insulin comes from the food we eat. People with this disease can not make the insulin needed for their bodies. Their pancreas sets up a blocking system, not allowing any insulin to form in their body. There is no cure for this disease. Having type one diabetes will mean you will need to inject insulin injections after every meal to keep your sugar levels in range.

Life is full of many obstacles that one must overcome to reach success in life. When I had just barely turned 14 years old I was posed with some of the toughest news I had ever faced. One week after my birthday, on Christmas Eve, I was diagnosed with Type 1 Diabetes.

Although currently it is only at a preclinical stage, xenotransplantation is needed to provide an unlimited supply of tissues and organs for transplantation. In the United States, “13 patients die each day waiting to receive a life-saving transplant to replace a diseased organ” The lack of donor tissues such as pancreatic islets is also increasing, statistics show that approximately 140 million people in the world have diabetes but only several thousand pancreatic glands become available annually. This shortage could be aided by xenotransplantation, for example using pancreatic islets from pigs. Xenotransplantation has the potential to completely eliminate the need for human organ donors as organs could be mass produced in animals such as pigs and harvested on demand, which would allow the stockpiling of viable organs for donation. The organs could also be genetically altered to be, for example, more strong or

Massimo Trucco of Children's Hospital of Pittsburgh, reported that transferring islet cells from a pig's pancreas into a human could be a cure for this disease (Mark Roth). In New Richmond, Wisconsin, a dynasty of pathogen-free pigs are being raised in a cinderblock bubble style building. These pigs are bred to generate an unusually large number of insulin producing islet cells that will eventually be a cure for diabetes (Marcothy). These cells can be replaced in a human from a pig's pancreas and supply an almost limitless supply of insulin. This limits the need for insulin

Researchers from Boston’s Children infused the produced excess PD-L1 into mouse models of diabetes. The treated stem cells of the rodents sped towards the pancreas

Type 1 diabetes (T1D) is a chronic disease, with no cure. Prior to the discovery of insulin by Banting and Best in 1921 and its subsequent purification by Collip and Macleod, T1D was a fatal disease. The availability of insulin was a major break-through and now is managed by frequent blood glucose (BG) tests and administration of insulin to treat or prevent BG outside the normal range. A bionic pancreas capable of frequently measuring blood glucose, automatically determining the proper insulin dose for each patient at each time point, and administering the appropriate insulin dose would revolutionize best glucose control management. Our research focuses on developing specific insulin bioassays for individual patients, and on the development

Diabetes is a disorder that affects millions of people in the United States today. There are two main types of diabetes including type 1, and type 2. Diabetes is caused by the body’s inability to produce insulin from beta cells. Beta cells are cells that can be found in the pancreas and regulate glucose levels. When glucose levels spike, beta cells are sometimes unable to continue producing adequate amounts of glucose and are destroyed in the process. In diabetics, the body’s immune system attacks the beta cells believing that they are foreign matter. When beta cells are destroyed, no insulin can be produced and can result in many symptoms including fatigue. Although this is an increasing problem today due to the increased levels of obesity, scientists have found a possible cure. This possible cure requires the injection of human embryotic stem cells in hopes that the cells can replicate and replenish the destroyed beta cells.

Stem cells, which have the ability to differentiate into insulin-producing cells (IPCs) either in vivo or in vitro, would provide a potentially unlimited source of islet cells for transplantation and alleviate the major limitations of availability and allogeneic rejection. Therefore, the utilization of stem cells is becoming the most promising therapy for

There are two types of diabetes: Type I and Type II that operate in slightly different manners. Type II is a result of an overload of insulin in the body, causing the immune system to attack the ?-cells whereas Type I is a result of an inability to produce insulin. Type I Diabetes is a chronic disease that is usually diagnosed in childhood and has a proven hereditary and genetic link. (ADA, 2005). Hence, current research on gene therapy is focused on the genes that can cause Type I Diabetes. In the last decade, gene therapy has emerged as an effective and very probable means of clinical intervention for victims of this life-altering disease. Gene therapy involves the integration of manipulated genetic material such as proteins or DNA into a cell to change its function. (Rudolph et al., 1996).