Type 2 Diabetes: Non Infectious Disease

Bckground While modern lifestyles and medical care have certainly improved the longevity of humans in the developed world, and contributed to a greater quality of life scenario, those same lifestyles have engendered a number of issues that contribute to disease. Lack of proper diet, fast food, high fat and carbohydrate diets without adequate fruits and vegetables, lack of exercise, smoking and alcohol contribute to an epidemic of obesity which, in turn, contributes to a serious metabolic disorder called Diabetes Mellitus Type 2. While not managed by insulin injections, it is nevertheless quite serious and has a number of progressing symptoms that, if not treated properly, can result in cardiovascular, renal and neurological problems, as well as amputation, ocular issues, and even cognitive dysfunction.

This essay will focus on type 2 diabetes, which is becoming one of the fast growing chronic health conditions in the United Kingdom (UK). Approximately 700 people are diagnosed with type 2 diabetes each day in the UK (Diabetes Uk, (2014)a). It is costing the NHS about £10billion pounds each year to treat diabetes along with its complication and it is expected to rise in the next couple of years (Diabetes UK, (2014)b).

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29 million people in the United States (9.3 percent) have diabetes, and of those 29 million approximately 7.25 million are unaware that they are diabetic (www.cdc.gov). Diabetes describes a group of metabolic diseases in which the person has high blood glucose because insulin production is inadequate, or because the body 's cells do not respond properly to insulin, or both. Diabetes can be divided into two groups: Type 1 diabetes and Type 2 diabetes. Type 1 diabetes is also referred to as juvenile diabetes and is usually found in children and young adults. Only 5% of people with diabetes have this form of the disease. Type 1 diabetes restricts the body from producing insulin, a hormone that is needed to convert sugar, starches and other food into energy needed for daily life. Type 1 diabetes can be managed by using insulin therapy and other treatments to help those infected maintain insulin to convert sugars, starches and foods into energy(www.diabetes.org). Type 2 diabetes is the most common, people with Type 2 diabetes have insulin resistance meaning the body does not use insulin properly. At first, the pancreas makes a surplus insulin to compensate for the lack on insulin in your body. However, over time your pancreas is not able to keep up and can not make enough insulin to keep your blood glucose at normal levels(www.diabetes.org). Complications of diabetes in the long term include potential heart disease, stroke, and kidney damage.

Non-infectious are caused by genetic, dietary, degenerative and environmental factors. These diseases are not caused by pathogens and are caused by lifestyle factors, environmental toxins and gene mutations. Non-infectious diseases cannot be passed between people. Many non-infectious diseases don’t appear till latter on in life.

Diabetes type two is a disease that affects millions of Americans every year. [Diabetes is a chronic disease. Alternate names for type two diabetes are, Noninsulin-dependent diabetes and Adult-onset diabetes (Wisse, 2014).]

More than three million cases in the United States. Type 2 Diabetes also called: adult

Diabetes Type 2 is a lifelong disease that develops slowly. Type 2 diabetes causes the person fat, liver and muscle cells not to respond correctly to the hormone insulin, as a result the glucose doesn’t get into these cells to be stored in energy, which causes the levels of blood sugar in the blood to increase and eventually causing damage to the nerves and small blood vessels of the eyes, kidneys and heart and lead to atherosclerosis or the hardening of the arteries which causes a heart attack or stroke. Common symptoms of diabetes type 2 is fatigue, hunger because the body can’t process the food properly so its expelled through urine, increased thirst because the person keeps peeing out everything they are consuming which makes them thirsty,

Diabetes is a chronic condition in which the body is unable to effectively process blood sugar in the body. The number of people who have diabetes has reached epidemic levels according to the Centers for Disease control and prevention. Over 110 million people in the U.S. alone have diabetes or prediabetes. About 95% of all diagnosed cases involve type 2 diabetes, and around 5% of all diagnosed cases are type 1 diabetes. Unfortunately, most people do not know that they have diabetes, and their condition can go unnoticed until they develop severe complications.

It is no secret that Diabetes type II is rapidly becoming a public health problem that is attacking epidemic proportions worldwide. In fact, according to an online article by the Washington post titled, “CDC Says Diabetes Numbers Increasing,” Author Stein, Rob claims that the federal Centers for Disease Control and Prevention has estimated that as of the year 2012, approximately 26 million Americans were clinically diagnosed with type II diabetes. Not to be confused type I diabetes however. Type I diabetes is where the body is typically insulin-dependent as beta cells are constantly attacked and destroyed by the immune system. Type II diabetes on the other hand, is where the body, may or may not make enough insulin; a hormone that serves to regulate the movement of sugars into the cells, and if it does make enough insulin, the body tends to not respond to it properly. In other words, one suffering from type II diabetes does not convert sugar into energy, but rather stores it in their bloodstream. This has caused type II diabetes to be the most common form of its type. As a result, those who suffer from type II Diabetes normally result in extra body-fat, hypertension, and high cholesterol.

Diabetes is a long-term metabolic condition characterized by high blood sugar levels. There are three major categories of the disease, type 1 diabetes occurs when the body produces minimal or no insulin, type 2 diabetes is when the body produces either little insulin or the cells are unable to respond to insulin, gestational diabetes mainly occurs during pregnancy. Non-Insulin Dependent Diabetes Mellitus, which is, type 2 diabetes is the most prevalent. The major complication that is caused by Type 2 diabetes is unremitting hyperglycemia, which leads to numerous changes in the body. There are several alterations in cellular, cardiovascular, and nervous functioning, which contribute to complications such as neuropathies and heart

“Diabetes causes 6 deaths every minute and one in 20 deaths in the world is due to the condition. Every year it is estimated that 3.2 million people in the world die due to the diabetes or its related causes.”

Even with the improvements in diabetes control and patient care, Type 2 diabetes is associated with a higher risk of death than the general population. For the current modelling analysis, the relative risk (RR) of death was estimated to be 2.45 for patients with DME and this was estimated based on the results from two studies. Mulnier et al. reported a RR of 1.93 (95%:CI: 1.89 to 1.97) for diabetic patients when compared to the general population.23 In the second study, Hirai et al., determined that the RR of death in diabetic patients with clinically significant macular edema was 1.27 (95%CI: 1.01 to 1.61).24 By combining the two estimates, the overall RR of mortality used in the model was 2.45 (i.e. 1.93 x 1.27).

Type two diabetes mellitus or non-insulin dependent diabetes mellitus is a disease state characterized by hyperglycemia or high levels of blood glucose. This can cause a variety of symptoms such as excessive urination or excessive thirst as the kidneys try to get rid of the excess sugar.. What distinguishes type two diabetes from type one diabetes is that a person with type two diabetes is not insulin dependent. Often times, there are decreased to normal levels of insulin detected in the bloodstream of humans with type two diabetes. The reason diabetes is developed is due to insulin insensitivity or a decrease in insulin production by the beta cells in the pancreas. Usually, patients with type two diabetes exhibit both insulin insensitivity and decreased insulin production. When the body does not react to insulin or when insulin levels are too low, sugar in the blood cannot be used effectively to create anabolic products such as glycogen, and it cannot be used as fuel because the glycolysis pathway is not activated. The high glucose levels that are then left in the bloodstream can cause blood to become very viscous and lead to many vascular diseases. If diabetes type 2 is not treated, then a number of problems arise such as numbing of the extremities, poor wound healing and decreased neurological function. Renal failure may also result as the kidney overworks itself to get rid of the excess sugar. Diabetes patients are also at risk of dehydration as they constantly

Type 2 diabetes is a very well known disease throughout the US. There are about 27 million people in the US with the disease and 86 million others have prediabetes which means their blood glucose is not right but also not high enough to be diabetes yet. 208,000 people under the age of twenty have been diagnosed with either Type 1 or 2 Diabetes.