Types And Classifications Of Pulmonary Hypertension

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Abstract Pulmonary hypertension is a disease that without treatment becomes progressively worse until a patient dies. It is characteristically a disease of young adults, but may occur all across the lifespan making this disease even more devastating.1 Pulmonary hypertension is characterized by elevated intrapulmonary pressures which cause dynamic changes to the cardiovascular system of the affected individual. The adequate functioning of the cardiovascular system is vital to the survival of the patient so while treatment is rarely curative, with the exception of organ transplant which will be discussed later, the main goal of medical therapy is to optimize cardiovascular functioning and stop disease progression allowing people living with this disease the best possible quality of life and level of functioning. There are several types and classifications of pulmonary hypertension with multiple pathogenesis. Different treatment modalities have been proven effective to treat this disease process; the mainstay of treatment relies heavily on pharmacologic therapies. Pharmacologic treatments include drugs in the following pharmacological classes: calcium channel blockers, prostacyclins including synthetic prostacyclins and prostacyclin analogues, endothelin receptor antagonists, and phosphodiesterase inhibitors. While pharmacologic therapies are the mainstay of treatment, heart and, or lung transplant maybe available for a specific subtype of PH, primary PH. Organ transplant is
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