There are four major types of blood groups that humans have: A, B, AB, and O. An individual’s blood type is determined by the type of antigens that are present in your blood cells; antigens are proteins and cause an immune response on the blood cells. The Rh antigen was discovered in 1940 by Karl Landsteiner and Alexander Weiner with the discovery of the cause of severe jaundice and fetal demise. The Rh antigen was named after rhesus monkeys, because they were the first used in the research of this antigen. The Rh blood group is the most important after the ABO blood group. “By the Mayo Clinic Staff, Rhesus (Rh) factor is an inherited protein found on the surface of red blood cells. If your blood has the protein, you 're Rh positive. If your blood lacks the protein, you 're Rh negative” (Mayo Clinic). Only fifteen percent of the population is Rh negative and out of the thirty five present human blood groups, it is one of the most complex systems. “The complexity of the Rh blood group antigens begins with the highly polymorphic genes that encode them” (Dean). There are two genes that have been closely linked together, RHD and RHCE, now over fifty antigens have been discovered, and research has showed that they can cause serious complications in the fetus of women who are Rh antigen negative. The most common antigens for Rh is D, C, E, c, and e. We have been able to have a better understanding of the Rh antigen because of the cloning of genes, and today we now know that the
There are four blood types found in humans. These are A blood type which has the genotype either AA or AO, B blood type which has the genotype either BB or BO, AB blood type which has the genotype AB, and O blood type which has the genotype OO. These genotypes show a combination of complete dominance and codominance. A and B traits are dominant to the recessive O trait, however, the A trait is codominant to the B trait. Each blood type codes for certain antigens. A blood codes for the A surface antigen, B blood codes for the B surface antigen, AB blood codes for both the A and B surface antigen, and O blood does not code for a surface antigen. Therefore to determine one’s blood type a test can be performed
13. Know the ABO and Rh typing system: what antigens are expressed, how one tests for the antigens, and the significance in transfusions, etc.
Type AB: The genotype is AB. The antigens on the blood cell are A and B. There are no A or B antibodies in the blood plasma.
To test the blood, we first dropped two drops of blood into two spots in a micro-well plate, then we added the appropriate serum to both and mixed with a small stick. One side was labeled A, for the A Anti-Serum, and one was labeled B. If the A blood clotted it meant that the A antigen was found, and likewise with B. If both clotted the blood type was AB, and if neither clotted the blood was type O. Some errors made
The goal of this experiment is to determine the blood types of the samples given and to learn what interactions occurred to each blood type. Determining an individual’s blood type and how it reacts with Anti A, Anti-B, and Anti Rh serums played a crucial part in this experiment. The researcher concluded that agglutination (clumping) occurred in some of the blood samples. For example, Mr. Smith’s blood reacted with Anti-A and Anti-Rh serums (antibodies) allowing the researcher to determine the blood type is A. Mr. Jones’s blood reacted with Anti-B serum but it did not react to Anti-A or Anti Rh allowing the researcher to believe that the blood type is B. Mr. Green’s blood reacted with all serums and caused a reaction to occur resulting the blood type to be AB positive. Mr. Green’s blood also had a positive marker for Rh factor. However, Ms. Brown’s blood had no reaction at all and the researcher determined if no reaction occurred then the sample had no antigens but proved to have some antibodies, resulting in blood type to be O. The purpose of this experiment is to determine whose blood has type A, B, AB, or O.
There are several genetic variants that give rise to rare D phenotypes. The Rh-null syndrome (also called Rh deficiency syndrome) is the result of a mutation that results in a lack of all Rh antigens. Since these antigens function to maintain the RBC membrane, individuals with this syndrome have abnormally shaped RBCs, leaving them at risk for hemolytic anemia. Rh-null patients are capable of forming antibodies to Rh antigens that can cause transfusion reactions; therefore they must receive blood from other Rh-null individuals.
Some blood disorders can be prevented while there are others that are out of a person’s hands and have to live with a blood disorder for a life time. It is essential to know the causes of hereditary disease and know how to treat them. It is also important to know what can be done to “cure” other blood disorders and what preventive measures need to be taken in order to stop history from repeating itself. Iron deficiency anemia, sickle cell anemia, and purpura simplex are just a few blood disorders that people suffer from that are either inherited or can be prevented.
This is very likely to determine whether Nikoleta’s abnormal red blood cell color and shape is part of a family history. It also notes that both parents have mild hypochromia and macrocytic anemia.
The purpose of this experiment is to identify the different blood types through the antigen and antibody reaction by using the anti- A, Anti- B and Anti- Rh serums we will be able to identify the different blood types. We will also discuss how this can be used in the clinical setting of this blood typing procedure, by doing so we will know how antigens and antibodies relate to the blood typing procedure in the real world settings.
Attributes of Catherine Catherine falls in love with a man at war who leaves her brave and heroic. She is also yet vulnerable and is willing to give up herself to be one with Henry. During this period, World War One was taking place in italy. Catherine meets an ambulance driver, Henry Frederic, and falls in love with him.
In 1900, Karl Landsteiner, a Viennese pathologist/immunologist was the first person to ever distinguish between the three different types of blood groups (A, B, and O). This combined with the advancement and growth of the Red Cross provided the support for the beginnings of blood transfusions for wounded soldiers.
Have you ever been bullied or called a name by someone? Andy Biersack Thinks strongly about bullying. Andy was born in cincinnati, Ohio on born December 26, 1990, and left high school because he was getting bullied for being different. Andy is a lead singer of the band black veil brides, a more then less rock band, who has performed on the warp tour. Andy has recently married Juliet Simms who has also performed on warp tour. At the beginning of Andy band he went by the name Andy Sixx.
The blood grouping systems commonly used include the ABO system that was first described by Karl Landsteiner. The discovery of blood grouping systems helped to avoid unnecessary death emanating from blood transfusion. The basics of blood grouping systems lie behind the inheritance of genes. The possession and inheritance of blood groups attribute to the parents who combine alleles responsible for the blood groups. The parents thus play a pivotal role in determining the blood groups of the offspring. This paper will work towards the discussion of inheritance of human blood groups.
It is very important for everyone to find out which blood type he has. A blood type test is the first thing should always be performed before a person receives a blood transfusion, donates blood, donates an organ for transplant, or undergoes surgery. For women who is trying to become pregnant it is necessary to know her blood type. It is possible for pregnant woman and her fetus to have different blood types. If the mother’s blood type is RH-negative and the baby’s is RH-positive, the mother’s immune system may develop antibodies that will attack the baby’s blood cells.
The global population is increasing exponentially. Enormous quantities of children are born each day and a small percentage is born into an adequate household. This drastically affects the global economy, society and the environment. As Margaret Sanger, founder of Planned Parenthood, said “more children from the fit, less from the unfit” (Sanger). Population control needs to be implemented through the enforcement of sexual education and greater access to contraceptives in order to decrease the number of births each year.