Types Of Skin Cancer : The Most Aggressive Form Is Melanoma Essay

     There are three main types of skin cancer. These are malignant melanoma, basal cell carcinoma, and squamous cell carcinoma. While melanoma is the most life-threatening of the three, it is also the most

Unlike other cancers which we can develop, melanoma can often be detected on the skin which allows doctors to treat it at its early stages resulting in less complications and lower death rates to patients, again if left undetected at its early stages this can easily spread to distant areas and distant organs. Once melanoma has spread to other areas of the body which is classified as stage IV it is diagnosed as

Melanoma is a dangerous invasive cancer which starts in melanin producing cells (melanocytes) usually located at the bottom of the skins epidermal layer. Although certain individuals have a genetic propensity for melanoma, it is usually triggered by excessive UV exposure from sunlight or tanning beds (Mayo Clinic, 2016a). At early stages it is relatively easy to treat, however, recurrences are common. At later stages melanoma treatments are less effective since it tends to metastasize and spread easily through the lymphatic system (Mayo Clinic, 2016a).. The root cause of malignant melanoma is due to mutations in the p53 gene protein which invariably leads to further mutations.

There are three primary layers of the skin: the outer layer, the epidermis and the layer beneath, the dermis and the hypodermis. The epidermis is thin, tough and waterproof while protecting the body from outside bacteria invading the body. It also contains keratinocytes which are from the basal layer which is the deepest layer of the skin. The keratinocytes reach up to the epidermis, shed and new ones form again. The dermis is the second layer of the skin and is the thickest. It is made from fibrous and elastic tissues which are made from fibrillin, elastin and collagen to create the strength and flexibility. It also contains sweat and oil glands, nerve endings, blood vessels and hair follicles. Sweat glands help the body cool off during heat

Melanoma is a malignant condition arising from melanocytes in the basal layer of the skin. Melanocytes are the cells that produce melanin, which gives skin its pigmentation and shields the deeper layers of skin from the damaging effects of ultraviolet radiation. When skin is exposed to ultraviolet radiation, melanocytes increase their production of melanin, which generates darker pigmentation of the skin. Ultraviolet radiation stimulates malignant changes within the melanocytes by mutating DNA, stimulating cutaneous growth factors, decreases immune defenses, and promotes species of melanin that cause DNA impairment and suppress apoptosis. The abnormalities caused by ultraviolet radiation in the melanocytes predispose it to

There are different types of skin cancer that people have to life with everyday who has them. The three different types are named from our skin cells where cancer can develope.

Melanoma is the most serious type of skin cancer. You can get melanoma from the sun, it can be genetic or from tanning beds. Melanoma is mostly on skin, but also found in eyes, under nails, and sometimes found in organs. It’s increasing to a lot of people under the age of 40, especially women. Melanoma can be in many places. Next, the sun and tanning bed increase your chances

Most skin cancers are caused by exposure to the sun. There are .non melanoma skin cancer, basal cell carcinoma and squamous cell carcinoma. The dermatologist examines for growths, moles, and dry patches. If the dermatologist finds what he thinks that looks like skin cancer a biopsy is taken. The sample of the skin that looks like cancer will be taken and sent to a lab.

"The rates of skin cancer have expanded consistently since the 1920s uncovers the risk of the American fixation on getting a "solid" tan. Skin tumor is an infection where growth (harmful) cells are found on the external layer of the skin (epidermis). The three sorts of cells found in the epidermis are squamous cells, basal cells, and melanocytes. These cells in time develop to be carcinogenic. Consequently, the three sorts of skin tumors are squamous cell, basal cell, and melanoma. Melanoma is the deadliest and dangerous kind of growth. The quantity of individuals with melanoma has ascended in Scotland from 3.5 in 1979 to 10.6 for each 100,000 in 1998 for men and 7.0 to 13.1 for ladies. (Mill operator 945) Squamous cell and Basal cell skin

Malignant melanoma is the most commonly seen skin cancer and it has the highest number of deaths among diseases of the skin (Friedman, Rigel, Kopf and Polsky, 2005). Among the many factors that cause this cutaneous cancer genetic modifications, viruses, carcinogens and excessive exposure to ultraviolet rays are the most commonly occurring (Friedman, Rigel, Kopf and Polsky, 2005). Malignant melanoma affects all areas of the skin and the disease forms in melanocytes, which are the cells in which pigments (melanin) are synthesized (Melanoma Treatment). The cancer has its origin in the epidermis and affect squamous and basal cells. The disease usually affects the trunk, arms and legs but can also be present in the eye, affecting the

Malignant melanoma of the nail apparatus is extremely rare but there have been a few cases reported. It seems that almost half of the population that has been diagnosed with this disease has been misdiagnosed or did not receive the proper treatment to cure the disease. Since the cases are easily misdiagnosed, fatality is usually the outcome for most. Survival rate of this particular disease in recent studies has shown that humans live on average five years after being diagnosed with melanoma of the nail. The disease can affect either the upper or lower nail extremities. The scientist tested seven people, three males and four females, to see how this disease effects each of the patients.

CAUSE: Melanoma is caused by a combination of genetic predisposition and external factors such as ultraviolet exposure. Heavy exposure to the sun is the most important factor in development of the disease. UV radiation causes damage to the DNA of cells, typically thymine dimerization, which when unrepaired can create mutations in the cell 's genes. Genetic analysis has shown that 92% of all melanoma are caused by this indirect DNA damage. This however does NOT mean that sunburn is the cause of this cancer. It is one of the rarer types of skin cancer but causes the majority of skin cancer related deaths especially if it is found late. At this time, the causes are not fully understood.

C. Melanoma Skin Cancer is the most dangerous form of skin cancer, it kills one person per hour, these cancerous growths are most often caused by ultraviolet radiation from sunshine or tanning beds. These tumors originate in the pigment-producing melanocytes in the basal layer of the epidermis. Melanoma is caused mainly by intense, occasional UV exposure (frequently leading to sunburn), especially in those who are genetically predisposed to the disease. Often the first sign of melanoma is a change in the size, shape, color or feel of a mole.

To sum up, cancer is one of the most serious diseases worldwide that has many kinds. The most serious kind of cancers is skin cancer. Melanoma is a severe kind of skin cancer that begins anywhere on the outer skin in cells which called melanocytes. Melanoma begins usually on the legs and on the trunk. There are several basic kinds of melanoma. For example, nodular melanoma, acral lentiginous melanoma, superficial spreading melanoma, and lentigo maligna melanoma. Melanoma has five various stages, which are stage zero, stage one, stage two, stage three, and stage four, and all these stages are categorized according on some criteria. Melanoma's causes are mainly separated into two different categories which are non-inherited and inherited causes.

Melanoma skin cancers are no fun for anybody, they can spread to other parts of the body, and they can be hard to remove through surgery. It is then important that the growth of such a cancer be blocked with any means. One of such means is the use of Debrafenib which is a generic name for Tafinlar. Tafinlar(Debrafenib) actively blocks or inhibits the growth of melanomar skin cancer.