Vaccines Are Promising Methods For Disease Prevention

1571 WordsOct 11, 20167 Pages
Pertussis is a highly contagious respiratory disease, and commonly known as whooping cough because of the uncontrollable coughing which follows infection. However, the immunization against pertussis has two vaccines; DPT and DTaP. DPT contains whole cell pertussis which is pertussis bacteria chemically and heat treated while the DTap version has less bioactive pertussis toxin, both these vaccines are also used to prevent diphtheria and tetanus. DTaP has replaced DPT in numerous countries as it has been deemed safer; DTap will also be the vaccine most referred to as the discontinuation of DPT makes it irrelevant to the purpose of determining whether or not countries should pursue the usage of pertussis vaccines. While vaccines are promising…show more content…
2009). This system only monitored individuals aged 10 – 64 years as this was the only demographic which could receive the vaccine. 3.3 million patients participated in the study, however only 660,000 received the TDaP vaccine and were the main focus. In order to determine whether or not the occurrence of encephalitis was relevant to the immunization, cases which happened within 1-4 2day risk window after the vaccination were considered relevant. The main disadvantage for this form of data collection is that it relied on an electronic hub for collection, and there was probable delay in updating patient files. To overcome this possibility, Yih et al. (2009) conducted another confirmatory analysis post-study period. Using statistical technology, Yih et al. (2009) set two values; critical value and an upper limit value. If the critical value is reached, the null hypothesis that there is no correlation between the DTaP vaccine and encephalitis cases would be rejected. However, if the upper limit value is reached prior to the critical value, the null hypothesis stands. The results of Yih et al. (2009) determined that the TDaP vaccine was not causal to encephalitis arrival as upper limits were reached before critical values. In addition, according to Yih et al. (2009)’s
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