Vitamin B12 As A Marker Of Cancer

A systematic search was conducted using PubMed and Google Scholar. The search was conducted using MeSH terms “statin therapy” AND “myopathy” AND “vitamin d” as well as the keyword “prophylaxis”. Limits included English only, humans only, years 2004 to present. UptoDate was searched for key words “statin-induced myopathy”, while Clinical Pharmacology was used for background information. Inclusion and Exclusion criteria were based on best available trials. While the best studies are randomized controlled trials,

B7 (Biotin): Depression, lack of intestinal absorption, inflamed bowel syndrome, skin irritation, hair loss, poor muscle control, seizures, development delayed

Vitamin B12 is important in the growth of cells. The body needs the cells to carry oxygen and nutrients to the body. B12 also works with the nervous system function. It makes up are bodies genetic material, and is essential for the production of red blood cells.

varied food supply make severe vitamin deficiencies unlikely but this doesn’t mean everyone gets enough of everything all the time. Marginal deficiencies often go unnoticed and can be mistaken for other conditions.

The purpose of a systematic review is to attempt to find, evaluate and synthesize high quality research relevant to the research question. A systematic review uses carefully developed data collection and sampling procedures that are put in place in advance as a protocol. (Polit, 2012). A systematic review must contain the following: a clear inclusion and exclusion criteria, an explicit search strategy, systematic coding and analysis of included studies, and a meta-analysis if possible. (Hemingway & Brereton, 2009). Systematic reviews are conducted by nurse researchers to avoid reaching incorrect or misleading conclusions that

This systematic review protocol is registered with PROSPERO, under the registration number CRD42017060339, and may be accessed online at

An increased MVC is a sign of a macrocytic anemia and is typically caused by folate and B12 deficiency, liver disease, hemolytic anemias, hypothyroidism, and alcoholism (Medscape, 2015). The risk factors for this type of anemia are the lack of meat and dairy products in one?s diet, intestinal disease, lack of intrinsic factor (IF), medications such as antacids or particular diabetes type II meds, and having an endocrine-related autoimmune disorder (Mayo Clinic, 2014). Her physical exam is negative, her asthma is well controlled, and she had no other complaints. Therefore, according to her physical exam, she appears to be a healthy young female. However, her lab values of Hemoglobin 10, Hematocrit 30.1, and an increased MCV are indicative of B-12 deficiency anemia. According to Buttaro, Trybulski, Polgar Bailey, & Sandberg-Cook (2013), mild cases of this type of anemia do not produce many symptoms, therefore, the complete blood count (CBC) usually verifies the diagnosis. The fact that she is vegetarian puts her at an increased risk for B12 deficiency, due to the lack of meat in her diet. Foods that contain B12 are only attained from animals such as meat, dairy, and fish. A deficiency from B12 from deficiency or malabsorption may not manifest for many years (Hunt, Harrington, & Robinson, 2014). The patient states that she does not drink

It synthesizes the results of various primary studies by using strategies that reduces biases and random errors. These reviews follow a strict scientific design and provide consistent estimates about the effects of interventions, therefore, conclusions are defensible. Systematic reviews shows where knowledge is lacking and can be used to guide future research. These reviews are usually carried out in the areas of clinical tests such as diagnostic, screening and prognostic; public health interventions; economic evaluations; adverse effects and how and why interventions work. Cochrane reviews are systematic reviews undertaken by Cochrane Collaboration members, aims to help people to make well-informed decisions about healthcare by preparing, maintaining, and promoting the accessibility of systematic reviews of the effects of healthcare

1. Is the article proposing to answer a specific clinical question or questions? What are the questions?

The study was a systematic review of scientific papers selected by a search of the SciELO, Cochrane, MEDLINE, and LILACS-BIREME databases. Among the 2169 articles found, 12 studies proved relevant to the issue and presented an evidence strength rating of B. No publications rated evidence strength A. Seven of the studies analyzed were prospective cohorts and 5 were cross-sectional studies.

To understand why the public’s health is in a precipitous decline it’s best to first look into the case of nutritional deficiency; are we getting all the vitamins and minerals our bodies require? One of the core issues is the misinformation on what a vitamin really is and why one should be concerned about this. The Food and Drug Administration has a firm stance that these synthetic vitamins

Both clinicians who are enquiring clinical questions and researchers who are conducting in-depth searches for systematic reviews come across a few

One of the most vital nutrients for good health is vitamin B12. It comes from animal foods and is responsible for big things such as the synthesis of DNA and the sheath that protects the nerve cells. There are lots of things you could be doing to deplete the essential B12 your body needs, including eating an unhealthy diet, smoking, and drinking, but there are also things like pregnancy and growing older that can be affecting how much B12 your body is getting.

I noted deficiencies in a number of vitamins in the January study. Calcium was only 0% of target levels, and potassium was well less than half of target levels. My sodium count was with the acceptable range, but just barely. I had deficiencies of iron, copper, and magnesium, but did acquire my recommended intake of phosphorous, selenium and zinc. I fell short on Vitamin A, Vitamin C, E, K, and

A study published in Archives of Internal Medicine found that 75 percent or more of American teens and adults are deficient in Vitamin D. That is why we have so many serious illnesses, like cancer, diabetes and heart disease (Huff, 2010).