Vitamin D Deficiency

852 Words Jan 25th, 2018 3 Pages
Several lines of evidence support a relation between seasonal variations in serum vitamin D and higher relapse rates in MS patients in winter.
Objective: To examine whether levels of vitamin D are associated with multiple sclerosis relapse.
Methods: In this study 60 patients in relapse and 60 patients in remission matched controls were included.
Results: patients in relapse had significantly lower 25(OH) D levels than 60 patients in remission matched controls (p= 0.004), Vitamin D insufficiency (<10 ng/ml) was significantly higher in patients in relapse compared to those in remission (p= 0.03).
Conclusion: The results of our study indicated that an association between lower serum 25-hydroxyvitamin D levels and higher risk of relapse among people with multiple sclerosis (MS).
Keywords: Multiple sclerosis, 25-hydroxy vitamin D

Introduction Multiple sclerosis (MS) is a neuroinflammatory disorder of the CNS, that most common affecting among young adults, particularly more prevalence in high-latitude regions (1-4), and believed to affect over 2 million people in the worldwide (5). Although the aetiology of MS remains unclear, but the prevailing thought is that MS is triggered by both genetic and environmental factors and their interactions have been implicated in developing MS (6). Vitamin D is a steroid vitamin that acts like a hormone and we get vitamin D from two sources: exposure to sunlight and food,…
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