Vitiligo: Chronic Skin Condition

In 1665, a scientist named Marcello Malpighi came up with the idea that the skin coloring was mainly dteremined from the granules of the stratum mucosum, not by those of the stratum corneum of the dermis. In 1879, Moritz Kaposi was the first man to observe the lack in pigmentation in the rete pegs of vitiligo. Rete pegs are epithelial extensions that project into the connective tissue in the skin and the mucous membrane. About 4000 years of knowledge about vitiligo has been recorded and observed from the time man first noticed the white patches appearing on the skin until the melanocyte was determined as the actor for causing the depigmentation in the skin.

Some people are born with more melanin than others. People with dark skin have more melanin than people with light skin. Some people are born with no melanin at all, and they are called albinos (Stewart, 10). Too much time in the sun produces extra melanin which protects the skin from the sun’s rays, and also makes lighter skin get darker, or suntanned. But if too much time is spent in the sun, it can result in a sunburn, and this can lead to skin

Melanoma is a malignant condition arising from melanocytes in the basal layer of the skin. Melanocytes are the cells that produce melanin, which gives skin its pigmentation and shields the deeper layers of skin from the damaging effects of ultraviolet radiation. When skin is exposed to ultraviolet radiation, melanocytes increase their production of melanin, which generates darker pigmentation of the skin. Ultraviolet radiation stimulates malignant changes within the melanocytes by mutating DNA, stimulating cutaneous growth factors, decreases immune defenses, and promotes species of melanin that cause DNA impairment and suppress apoptosis. The abnormalities caused by ultraviolet radiation in the melanocytes predispose it to

The symptons include facial disformities including downward slanting eyes, smaller lower jaw (also referred to as micrognathia),underdevloped zygoma, drooping

Vitiligo is a skin pigmentation disorder. This disorder can be recognized by the presence of the patches and macules that are depigmented. For instance, someone with darker skin will have white patches among their body, as well as some white hair. Melanoma Associated Hypopigmentation is also a depigmentation of the skin, but it can be associated with immunotherapeutic agent treatments. Vitiligo and Melanoma Associated Hypopigmentation are both leukodermas. They also seem to link to MM which is Malignant Melanoma.

Vitiligo is a continual and long term skin problem that causes white depigmentation on your skin. The white patches appear due to melanocytes within the skin dying off. Melanocytes are cells that reproduce causing pigment, if you lack melanocytes then you will have white patches. Melanin, which gives your skin color also protect you from the sun’s UV rays. Vitiligo affects people differently; there is not an exact place where you can have it. You can have it all over your body, hair, mouth, and even eyes.

Melanin is an important part of the body that is produced by melanocytes. Melanin gives the hair, skin, and eyes color as well as protects the body from the ultra violet rays that radiate from the sun. The amount of melanin in the body determines the complexion of the skin. Vitiligo occurs when these important melanocytes die in patches around the body. This differs from the aging process, when melanocytes stop producing melanin which results in white or gray hair. Vitiligo is a non-contagious, non-life-threatening condition which causes a discoloration of the skin that appears over time, but does not go away. Most people say this condition is painless, but some report itching, and pain. This condition affects millions of people around the world, proportionately between men and women, and can be present in any given race, although it is more apparent in darker skin

Also known as an autoimmune disease, that attacks the body that destroys the melanocytes in the skin, or they will destroy themselves. Melanin is an important pigment that gives the skin its main color.

Vitiligo is a disorder which , in the skin destoryed. Sometimes the genes of the immune system can play a role in this diseases. People the have vitiligo

Vitiligo has always sparked my interest because the causes behind this rare appearance are bewildering. Vitiligo causes an individual to loose pigment in his or her skin, but is not deadly. Loss of pigment is caused when melanocytes die. Oddly, vitiligo showcases no other symptoms and researchers are baffled by why the cells die. Although there may be a correlation between non-segmental vitiligo and auto immune diseases. Diagnoses of vitiligo vary and display in different parts of the body such as the hair, eyes, mouth and skin. Two types of vitiligo exist and each has a different severity. Segmental targets a specific part of the body such as a leg, arm or face and begins at an early age. Eventually segmental vitiligo stops spreading after

Vitiligo is a disease of the Integumentary system that causes white patches on the skin, these patches are caused by the absence of melanin. Melanin is the skin pigment that gives you color; therefore, these patches are much more noticeable it darker skinned people. Vitiligo only affects about 1%-2% of the population. Most people who have this condition have it for a lifetime, although there are treatments that may help.

Subtype 1: erythematotelangiectatic rosacea. This subtype is characterized by flushing and persistent erythema in the center of the face. Telangiectatic vessels are common and in more severe grades are usually prominent on the cheeks and nose, contributing to facial erythema. Factors that trigger flushing (eg, stress , certain foods, alcohol, menopause) usually are revealed during the medical history (Powell, 2005).

Vitiligo has two classes which are the Integumentary and Dermatological. What happens during this disease will make you feel very lucky to have the same skin color, the people that have Vitiligo are the ones who have different splotches of skin color. This disease is caused by the loss of dead melanin cells which stops the production of skin pigmentation. The symptoms of the disease is the discoloration in the eyes, arms, legs, other parts of the body. The worst symptoms are hearing loss and a bigger chance of getting skin cancer. Like the other two diseases that I have researched, Vitiligo does not have a definite cure. There are treatments that you can purchase to help slow down the discoloring development skin graphing and different types of light therapy. One of the most famous cases of Vitiligo is a celebrity who had it was Michael

The destruction of melanocytes can have three major causes in people with vitiligo. The first being that a patient with vitiligo has inherited three of the “vitiligo” genes, which has caused their melanocytes to destruct. The second being that the melanocytes themselves are different in a patient with vitiligo in relation to those without vitiligo. Melanocytes of a vitiligo patient compared to a person without vitiligo require a meticulous cultural condition and are more unstable around certain chemicals. The cells can even die when exposed to such factors. Vitiligo genes are prevented from acting in a normal fashion when they are

Vitiligo is defined as an autoimmune disease with a strong genetic component, characterized by areas of depigmented skin resulting from loss of epidermal melanocytes (Changbing, 2016). The term vitiligo derives Latin and was first used by Celsus in his De Medicina (Iannella, 2015). This disease causes the loss of skin color and it becomes blotchy. The extent and rate of color loss from vitiligo are uncertain. It can affect the skin on any part of the body examples would be hair, the insides of the mouth and even the eyes (Mayo Clinic Staff, 2015). Normally, the color of hair, skin and eyes is determined by melanin. Vitiligo occurs when the cells that produce melanin die or stop functioning (Mayo Clinic Staff, 2015). Melanin is responsible for giving humans their skin, hair and eye color, this pigment is mainly composed of melanocytes cells in the skin and is sometimes referred to as a chemical as part of the metabolizing process of an amino acid called tyrosine. Vitiligo can affect people of all skin types, but is general found common on lighter people but those with darker skin are more prone to this disease and it is more noticeable.