Vitiligo Research Paper

It develops in the melanocytes, which are cells that produce melanin that gives the skin its pigment or color and protects tissues from ultra violet radiation. Dark skinned people have more melanin than light skinned people do. For this reason, Melanomia is more frequent in light skinned people. (“Detailed description “, 2000, P.2

The basic component in tanning is ultraviolet light. Ultraviolet light, whether produced by a tanning unit or by the sun, contains two components; UVA and UVB. These are the two types of ultraviolet radiation that are known to negatively effect the skin. UVA has a longer wavelength that causes photoaging and can produce some melanomas. UVB has a shorter wavelength that also causes photoaging and has been implicated in skin cancers. Photoaging is the premature aging or deep wrinkling of skin. Indoor tanning units utilize both forms of light waves to tan a person with a minimized risk of sunburn. Tanning outdoors does not give you this option because the sun omits every type of UV rays, so a person is more likely to burn. A person’s skin epidermis consists of two layers: The germinative layer and the horny layer. Another name for the germinative layer is the “living layer.” And another name for the horny layer is the “dead” layer. When exposed to ultraviolet light, melanocytes in the germinative layer produce melanin that is absorbed by surrounding cells. Melanin is a dark pigment found in the pigment-bearing cells of the skin, and melanocytes are epidermal cells capable of synthesizing melanin. This creates a protective barrier from ultraviolet light reaching deeper into the layers of the skin. The pale pink melanin granules are stored in the core of keratin cells. UVA darkens the melanin,

Melanoma is the most dangerous type of skin cancer. It develops when unrepaired DNA damage to your skin cells trigger genetic defects that lead you skin cells to multiply at a fast pace and form tumors. Melanoma can often resemble moles and some can come from previous moles. These melanoma moles can range in color from pink, red, brown, purple, white, blue and skin-colored, but more mostly seen as black or brown. It’s said that consumers who use indoor ultraviolent tanning devices are seven-four percent more likely to develop melanoma compared to someone who has never used a tanning bed before. Melanoma is usually caused from intense and over exposure to UV radiation. It has be estimated to kill around 10,000 individuals in the U.S. each year. The lifetime risk of melanoma is 1.5 times higher in males than in females. Melanoma is curable, if it is recognized early and

In 1665, a scientist named Marcello Malpighi came up with the idea that the skin coloring was mainly dteremined from the granules of the stratum mucosum, not by those of the stratum corneum of the dermis. In 1879, Moritz Kaposi was the first man to observe the lack in pigmentation in the rete pegs of vitiligo. Rete pegs are epithelial extensions that project into the connective tissue in the skin and the mucous membrane. About 4000 years of knowledge about vitiligo has been recorded and observed from the time man first noticed the white patches appearing on the skin until the melanocyte was determined as the actor for causing the depigmentation in the skin.

Two times of melanin are produced within the body, one is called eumelanin and it is responsible for the golden brown color we normally associate with tanning. Another pigment is called pheomelanin and it produces a red color. Redheads and blondes produce more pheomelanin and less eumelanin, which is why they don't tan as well. Sunlight and ultraviolet rays affect the pituitary gland, a gland at the base of the brain that secretes hormones, which then produces melanocyte-stimulating hormone. This hormone flows through the bloodstream to the melanocytes, which makes them able to produce more melanin. (The Science of Tanning)

Surprisingly, the sun-kissed tanned skin is what most younger whiter complexions are eagerly trying to desire; despite the risk of artificial tanning that could cause to a person’s health, but the rate of people using a tanning salon is still rising. In America, there are 30 million white females from ages 16 to 29 years old that are fascinated in indoor tanning (Becirevic, Amel et al, 2017). As the rate of tanning bed users rises the melanoma incident has also increased. Melanoma risk is associated with artificial tanning for a very long period of exposure to the ultraviolet radiation which skin problem can occur later in life. People used artificial tanning as it gives very quick result for a brief period and the fewest number of sessions

Bethell, E. (2005). Wound care for patients with darkly pigmented skin. _Nursing Standard, 20_ (4), 41-49. Retrieved April 14, 2006, from OVID MEDLINE database.

Some people are born with more melanin than others. People with dark skin have more melanin than people with light skin. Some people are born with no melanin at all, and they are called albinos (Stewart, 10). Too much time in the sun produces extra melanin which protects the skin from the sun’s rays, and also makes lighter skin get darker, or suntanned. But if too much time is spent in the sun, it can result in a sunburn, and this can lead to skin

Melanin is the pigment in the skin that absorbs ultraviolet light and protects the skin from sun damage, so the less pigment in a person’s skin the less protection they have

The article “Melanoma: Causes, Symptoms, and Treatments” written by Markus MacGill and reviewed by Dr. Helen Webberley is exactly what it states, an article on the integumentary disease melanoma. This article tells everything about melanoma, stating that it is a very deadly type of skin cancer. It is fortunate that it is the least common, however it is still responsible for the majority of skin cancer related deaths each year. Melanoma comes from pigment-producing cells that have mutated into a cancerous cell. They spread quickly, almost too quickly to catch. Skin cancer is first noticed by the look of the skin, then can be confirmed or denied with testing. Melanoma may not produce symptoms. Staying out of the sun for extended amounts of time is best when avoiding skin problems, especially skin cancer. Melanoma is seen mostly in people over the age of forty, and favors women. It can develop anywhere on the skin but does favor the trunk of men and the legs of women. Melanoma will form changes in existing moles on the skin. People should be checking for noticeable differences in skin constantly, especially those who have a known risk. Some early indicators of melanoma could be pale skin, light eyes, numerous moles, multiple freckles, sun exposure, light hair, age, and a few more. Sadly, most these are unavoidable.

Vitiligo is a continual and long term skin problem that causes white depigmentation on your skin. The white patches appear due to melanocytes within the skin dying off. Melanocytes are cells that reproduce causing pigment, if you lack melanocytes then you will have white patches. Melanin, which gives your skin color also protect you from the sun’s UV rays. Vitiligo affects people differently; there is not an exact place where you can have it. You can have it all over your body, hair, mouth, and even eyes.

Melanoma is a form of skin cancer that arises from the production of melanocytes (cells that create pigment) found in the hypodermic tissue deep within the skins layer. When the cells become damaged or mutated, rapid reproduction occurs forming a tumor. It is most commonly developed on areas of the skin that have been exposed to the sun over a period of time, such as the face, arms, back and legs. However, it can develop anywhere on the body and in the most unlikely places, such as the mouth, palms of the hands and soles of the feet. The most common cause of melanoma is from UV radiation emitted from the sun, but it can also be from environmental and genetic factors as well.

Vitiligo is a persistent dermatological condition in which patches of the skin become depigmented. Affected areas lose their natural color and appear noticeably pale. Vitiligo treatment helps alleviate the stigma felt by many people affected by this condition. There is no permanent cure, but cosmetic remedies help many people improve their appearance and feel better about themselves.

A major function of melanin is to act as a defensive barrier of the skin against radiation damage. Ultraviolet light between the wavelengths 280-320nm (UV-B) causes sunburn and damages the skin on nonpigmented peoples. Exposure to this degree of light causes their skin to become dry, leathery, and wrinkled in appearance similar to that associated with aging. This can be seen in Whites living in Australia and South Africa, where ultraviolet light intensity is high because of the relative latitude or closeness to the equator.

Red, raised, dry, inflamed, scaly areas on the body and the pitting of the nails describe the common appearance of the pathological disease of psoriasis. Doctors often find it difficult to determine psoriasis because it is very similar to other skin disorders. There are several ways to confirm its medical diagnosis, dermatologist may analyze your skin, nails, and scalp (Langley, 2010). A dermatologist is a specialist trained in skin diseases. If not determined by the naked eye, further investigations are needed to determine the type of psoriasis. It can be tested by a biopsy of the skin which is performed by examining the skin under a microscope, x-rays could determine joint swelling or joint deformity, a blood test to determine arthritis, and medical history.