Vitiligo Research Paper

It develops in the melanocytes, which are cells that produce melanin that gives the skin its pigment or color and protects tissues from ultra violet radiation. Dark skinned people have more melanin than light skinned people do. For this reason, Melanomia is more frequent in light skinned people. (“Detailed description “, 2000, P.2

An example of an area would be in the European areas, where the UV radiation doesn’t beam down as strong onto our skin. If it was another hot open area such as Australia then the skin pigmentation stayed darker. In short, the skin pigmentation adapted to the lifestyle and the surround environment to better help survive in that climate. This is due to the body producing more melanin so the effects of the sun’s rays can be counteracted. Through generations successful genes are passed through the blood line, the human body also has a tendency to produce a particular amount of melanin depending on the location of where one

In 1665, a scientist named Marcello Malpighi came up with the idea that the skin coloring was mainly dteremined from the granules of the stratum mucosum, not by those of the stratum corneum of the dermis. In 1879, Moritz Kaposi was the first man to observe the lack in pigmentation in the rete pegs of vitiligo. Rete pegs are epithelial extensions that project into the connective tissue in the skin and the mucous membrane. About 4000 years of knowledge about vitiligo has been recorded and observed from the time man first noticed the white patches appearing on the skin until the melanocyte was determined as the actor for causing the depigmentation in the skin.

If case of exposure to the sun during the first year of formation, a keloid can be tan darker than the surrounding skin.

Idiopathic disorders as Vitiligo may be confused with PA. Vitiligo is an acquired pigmentary disorder of the skin and mucous membranes that is characterized by circumscribed, depigmented

The skin disorders that might results from hereditary, congenital, or acquired pathological processes are ichthyosis, bullous diseases, chronic infections of the skin, dermatitis, hiradenitis suppurativa, genetic photosensitivity disorders, and burns.

Vitiligo is a skin pigmentation disorder. This disorder can be recognized by the presence of the patches and macules that are depigmented. For instance, someone with darker skin will have white patches among their body, as well as some white hair. Melanoma Associated Hypopigmentation is also a depigmentation of the skin, but it can be associated with immunotherapeutic agent treatments. Vitiligo and Melanoma Associated Hypopigmentation are both leukodermas. They also seem to link to MM which is Malignant Melanoma.

An improperly kept skin attracts the gathering of dead skin cells inside the pores, clogging the pore opening and triggering oil build-up (blackheads).

Vitiligo is a continual and long term skin problem that causes white depigmentation on your skin. The white patches appear due to melanocytes within the skin dying off. Melanocytes are cells that reproduce causing pigment, if you lack melanocytes then you will have white patches. Melanin, which gives your skin color also protect you from the sun’s UV rays. Vitiligo affects people differently; there is not an exact place where you can have it. You can have it all over your body, hair, mouth, and even eyes.

Melanin is an important part of the body that is produced by melanocytes. Melanin gives the hair, skin, and eyes color as well as protects the body from the ultra violet rays that radiate from the sun. The amount of melanin in the body determines the complexion of the skin. Vitiligo occurs when these important melanocytes die in patches around the body. This differs from the aging process, when melanocytes stop producing melanin which results in white or gray hair. Vitiligo is a non-contagious, non-life-threatening condition which causes a discoloration of the skin that appears over time, but does not go away. Most people say this condition is painless, but some report itching, and pain. This condition affects millions of people around the world, proportionately between men and women, and can be present in any given race, although it is more apparent in darker skin

It is a fact that melanin plays a major role in giving us a color for both of our skins, hair, and eyes. For instance, dark-skinned people have a larger amount of melanin that what light-skinned people have. In addition, it is responsible for the tan of our skins that are exposed to the sunlight. Indeed, it is important to start this research by giving some scientific definitions that describe the melanin in detail. First, melanin is a type of cells that controls a wide-range of essential functions in our bodies including control of organs cyclical rhythms, melodious, and energy conversion.

It was first discovered long ago in 1500 B.C by the Egyptians and took many centuries to figure out what was happening to the skin. Sun exposed areas will most likely be the first spot vitiligo is seen which are the hands, feet, arms, face, and lips. Later on other places on the body start to get the white patches as well. Also there could be premature whitening or graying of the hair on their scalp, eyelashes, eyebrows or beard. There are many methods a doctor can do to see if someone has vitiligo and there are a few treatments that can control the disorder. Vitiligo is harmless and can not usually be

Treatment of vitiligo is done to control the progress of the disease and to achieve repigmentation in lesions that have formed. An effective form of therapy is targeted UVB phototherapy which is based on the finding that ultraviolet light can induce melanin synthesis leading to repigmentation. Melanocyte loss in vitiligo is caused by immune attack operated by melanocyte-specific T cells, innate immunity, and melanocyte-specific antibodies [5]. The therapy helps initiate a process known as neo-melanogenesis in which melanoblasts multiply and travel along the infundibulum outer root sheath to the interfollicular epidermis in order to repopulate the epidermal areas as a response to DNA damaged by UV light. (Brenner

Human pigmentation is influenced by hemoglobins within blood vessels in the skin, carotene and melanins. Melanin, the basis of pigmentation, can be found in the forms of eumelanin and phaeomelanin. Eumelanin is the brown-black pigment located in the skin, hair, and eyes. Phaeomelanin is a yellow to reddish-brown pigment found in small quantities within the skin, eyes, and red hair. Because of these two pigments, to a greater or lesser degree, we have the variation

Skin Bleaching is defined as a practice of using chemical substances in attempt to lighten skin tone or provide an even skin complexion by lessening the concentration of melanin. There are several methods in which this can be achieved from the use of topical creams and gel, chemical peels and even skin whitening pills known as Glutathione. This practice is dated as far back as the 1200s rooted in Asia and Japan which is called the Asian Whitening and the Renaissance period between (1400s-1600s), all these people where already of Mongolian and European descent but where