Volumetric Mri, A Future Tool For Diagnosing Alzheimer 's Disease?

Alzheimer disease (AD) is the most common cause of dementia in the elderly, accounting for 65–70% of all cases (Jellinger, Janetzky, Attems, & Kienzl, 2008). The other dementias are of the Parkinson 's group, the fronto-temporal group and the vascular group. The total worldwide yearly costs for the treatment and care of patients suffering from dementia are estimated to be around 250 billion US dollars. The lifetime risk for AD between the ages of 65 and 100 is 33% for men and 45% for women with an annual increase of 1–2% in the seventh decade to almost 60% in the 10th decade with doubling every 5 years (Jellinger et al., 2008). AD is incurable, and thus represents a major public health problem. AD represents a challenge to humanity due to its relatively recent discovery, progressive nature of the illness, and complex diagnosis.

The disease called Alzheimer’s is the fourth leading cause of death in the United States (Weiner, 1987). It is estimated that the elderly population will double between now and 2030. During this period, the number of elderly will grow by an average of 2.8% annually (U.S. Census Bureau, 2001). By 2050, the number of people with Alzheimer’s is estimated to range from 11.3 million to 16 million (Alzheimer’s Association, 2005). These startling numbers should prompt an examination into one of the leading causes of death among this group of people. Understanding what Alzheimer’s is and the known causes of the disease are a good starting point. For those who have aging family members, knowing the risk factors and warning

The brains of Alzheimer patience slowly degenerate. Their nerve cells stop functioning and important brain operations cease. According to the National Institute of Neurological and Communicate Diseases,

Alzheimer 's disease (AD) is a progressive degenerative disease of the brain from which there is no recovery. There are three brain abnormalities that are the hallmarks of the Alzheimer’s disease is initially caused by plaques buildup in the brain’s neurons as illustrated in figure 1. The support structure that allows the flow of the nutrients through the neurons gets damaged and ultimately there is loss of connection among the neurons and they die off (National Institute of Health, 2015). This causes the brain tissue to shrinks, which is called atrophies. All this ultimately lead the victim of this disease to face difficulties in governing emotions, recognize errors and patterns, coordinate movement, and remember. Ultimately, a person with AD loses all memory and mental functioning.

People with Alzheimer disease also develop deposits of protein and fibre that prevent the cells from working properly. When this happens, the cells can't send the right signals to other parts of the brain. Over time, brain cells affected by Alzheimer also begin to shrink and denature.

Alzheimer's disease is one of the most common causes of dementia. The term 'dementia' describes a set of symptoms, which can include memory loss, changes in mood and problems with communication and reasoning. These symptoms occur when certain diseases and conditions, including Alzheimer’s disease, damage the brain. Alzheimer's disease could be described as a physical disease affecting the brain. During the course of the disease, protein 'plaques' and 'tangles' develop

Alzheimer’s Disease is a form of dementia affecting more than one third of those over ninety-five years old. Its effects vary per person and become systematically more extreme as time wears on. Alzheimer’s is currently incurable and impossible to slow, destroying neurons and brain tissue, resulting in loss of memory, judgment, awareness, communication, behavior and capacity for emotion. Changes in personality and loss of initiative are also common symptoms of Alzheimer’s.

     Dementia, memory loss, and cognitive breakdown are some of the major signs and symptoms of Alzheimer’s disease. The disease damages brain cells, which in turn, impairs the memory and leads to loss of memory and the ability to perform tasks. The slow elimination of cells weakens the brain’s ability to remember things, perform normal

Alzheimer’s disease is a progressive brain disease which slowly destroys thinking and memory skills. These changes are severe enough to interfere with day to day life. This irreversible disease is the most common cause of dementia amongst the elderly, with an appearance of first symptoms after age 60.

     Alzheimer’s disease is a progressive degenerative disease that attacks the brain and results in impaired memory, thinking and behavior. Alzheimer’s is the most common form of dementia. Dementia is the lost of thinking, remembering and reasoning so bad it screws up ability to do daily functions and eventually resolves in death. Dr. Alois Alzheimer’s first discovered the disease in 1906. Since then research has developed a deeper understanding of the changes in the brain. Warning sign’s of Alzheimer's are memory loss that affects home and job skills, problem in speaking, poor judgment, and difficulty in learning. The last stage of Alzheimer's disease is when you’re unable to take care of

Alzheimer’s, the most relevant cause of Dementia, is a disease that affects as many as 4.5 million Americans per year (WebMD 2005-2014). Alzheimer’s is a disease that is an irremediable, continuous brain neuron degenerative disease that can be asymptomatic at first and then overtime becomes symptomatic. Alzheimer’s is a gradual disease that advances in three phases: mild, then moderate, and, finally, severe (1). Symptoms appear after the age of 60 and include: the slow destruction of memory and thought processes, and ultimately ends with the absent ability to do normal everyday duties. These symptoms can be anything from forgetting a recent event, or can be as problematic as forgetting the name of a family member. There are many daily

“Alzheimer’s disease is a progressive condition that destroys the connections between cells in the brain.” (WebMD, 2014). As the cells die the cortex shrinks. The part of the brain that is impacted the most in dementia is the cortex. The cortex includes the hippocampus. This helps new memories form. If there is damage to this part of the brain, there will be problems with the person memory.

There are many different symptoms of Alzheimer’s. At first you will start to get confused more easily and forget things more often. How fast symptoms worsen is different from one person to the next. One of the symptoms is memory loss. People with Alzheimer’s will start to repeat their sentences and ask questions several times without realizing they had already said it. People will forget where they put things (example: keys, TV remote, etc,...). When Alzheimer’s gets worse, the person might start to forget who people are and what their name is.

Although some kinds of memory loss are very normal in the aging process, the changes that are caused by aging are not that extreme enough to conflict with it. A number of certain diseases and conditions can cause dementia. These conditions and diseases consist of Parkinson’s disease, strokes, brain tumors, blood clots and Multiple Sclerosis, but the most common disease to cause this is Alzheimer’s disease (Crystal, 2009).

In a brain effected by Alzheimer’s the cortex starts to shrivel up the most common areas that are damaged are the areas used for thinking, planning and remembering. The cerebral is a thin layer of grey tissue the cortex id grey because the nerves lack the insulation that can be found in other areas making it white. When examining the cortex it can be divided in to four separate lobes the cortex takes up the majority of the brain . It is the most highly developed part of the human brain and is responsible for thinking, perceiving, producing and understanding language. The cerebral cortex is also the most recent structure in the history of brain