What Is Inorganic Arsenic?

While nitrates are one of the major contaminants in the area, San Joaquin Valley residents face drinking water pollution from many other sources including arsenic, coliform bacteria, and pesticides. Arsenic is a naturally occurring semi-metal element that is found in different types of rocks. While arsenic primarily occurs naturally, human activities impact the amount of arsenic in groundwater. Arsenic is not only toxic at high concentrations, but also harmful after prolonged exposure at moderately elevated levels. California recognizes arsenic as a human carcinogen and believes prolonged exposure to the element to be associated with various cancers, including skin, bladder, kidney, lung, and liver cancers. A study in Maine found a connection between water contaminated

The health hazards for humans who come in contact with contaminants from exposure to polluted water can have long term effects on the body causing possible organ failure and death. Contaminants and chemicals such lead and mercury can bring about many minor illnesses ranging from nausea, lung irritation, skin rash, vomiting, and dizziness, to the major diseases that include cancer, liver and kidney damage, disorders of the nervous system, damage to the immune system, birth defects and even death.

There is a higher likelihood of being exposed to arsenic via food ingestion compared to inhaling arsenic-contaminated air or drinking arsenic-contaminated water. Once the arsenic has been absorbed through the lungs or gastrointestinal tract, the arsenic is distributed through the body via the bloodstream. For metabolism, in the blood stream, the arsenic becomes attached to the red cells, white cells, and cells that can convert arsenate to arsenite. Some of those arsenites are taken to the liver, where they are methylated by the enzymatic transfer of the methyl group from S-adenosylmethionine (SAM) and the arsenite are converted into methyl arsonate (MMA V) and dimethyl arsenate (DMA V). Those metabolites, methyl arsonate and dimethyl arsenate, are then ready to be excreted. If the liver is at its limit of methylation, excess arsenites are stored in the body’s soft tissues. Arsenic and its many variations (ie. MMA V, DMA V, arsenate, and arsenite) are excreted through the kidneys. There is a possibility that two to four weeks after being exposed to arsenic, some of the arsenic can still be found in the human’s hair, nails, skin, and bones and teeth (ATSDR,

illegal level of bacterial growth. This study also found high levels as high as 13 parts per billion of arsenic tap water is only allowed to have 5 parts per billion.

This chemical tends to occur naturally in soil, so sometimes it can make its way into your well. If you drink too much water contaminated with arsenic, you will be susceptible to an array of harsh side effects such as vomiting and a burning feeling. If your water supply is never checked and you drink arsenic-laced water regularly over time, your risk factor for developing several kinds of cancer will increase substantially.

If it would have a health impact, it must also have an economic factor too because of all the cures and medicine it has to be dealt with. Arsenic does have some presence in air, which mostly is produced from flamming-hot temperature such as volcanoes, mining and more( the form of arsenic that is produced is Arsenic Trioxide). Air is very exposing to all of us ,we breath it every second, an essential part of life and when Poison is released into the atmosphere, it spreads very fast and very un-noticed. You cannot see the particles and chemicals in the air but can only possibly feel it. By the time you feel arsenic, it would be a pain response from the nerve and is already poisoning

Arsenic is a ubiquitous carcinogen that is both produced commercially and prevalent in nature. Its clinical harms to humans include hypertension, cardiovascular diseases (Chen 53; Chen 342; Tseng 15) and diabetes as well as typically skin, lung and bladder cancer (Rohan 7; IPCS 521). Given its toxicity and its potential to contaminate water, air, and soil from both geological and anthropogenic sources, it is therefore of significant environmental concern. This paper aims to discuss the harms and benefits of Arsenic by comparing Rachel Carson’s account of Arsenic in Silent Spring to modern research. It is noteworthy that although her findings are largely accurate, it fails to account for the benefits of Arsenic to human health as a form of specialized treatment. This paper will also present reasons as to why in spite of the rise of immunotherapy as an alternative treatment to Arsenic while avoiding risks of Arsenic, its prohibitive costs implies that Arsenic still has a role in making specialized medical treatment accessible to particular patients. Namely, the following questions will be answered:

Mixed contamination of benzo[a]pyrene (B[a]P), arsenic (As), cadmium (Cd), and lead (Pb) is a major environmental and human health concern. The mixture toxicity data on these co-contaminants are important for their risk assessment. In this study, we have determined the mixture toxicity of As, Cd and Pb and B[a]P with As, Cd or Pb in HepG2 cells. The binary mixtures of Cd + As, Cd + Pb and As + Pb and B[a]P + metals (B[a]P + As, B[a]P + Cd and B[a]P + Pb) were evaluated for their interaction on the cytotoxicity using the MTS assay. A full factorial design (4 × 5) was used to determine the interaction toxicity and all the six mixtures showed significant interaction on the cytotoxicity. We further investigated the role of oxidative stress (reactive

Arsenic, element number thirty-three on the periodic table, is well known as a poison. There are two forms of arsenic, organic and inorganic, which is considered more toxic than its organic form itself. This element is a natural metal found along the earth’s crust. It is found in rock, soil, water, and air. Arsenic can enter the body through two ways: ingestion and inhalation. When arsenic is ingested it goes through the gastrointestinal tract where 95% of the arsenic dose is absorbed. When arsenic does come out of the body it is able to come out through some ways such as: feces, sweat, and urine. (Unknown, 2015)

The primary sources for arsenic in the general population include contaminated water, food, and soil. The two forms of inorganic arsenic include: trivalent arsenic (As III) and pentavalent arsenic (As V). The most common inorganic form of arsenic in the environment is pentavalent arsenic. When comparing toxicity, trivalent arsenic is approximately 2-10 times more toxic pentavalent arsenic. Arsenic poisoning produces effects on multiple body systems with the inorganic forms being highly toxic. Both trivalent arsenic and pentavalent arsenic have different mechanisms of action, which determines the effects they have on cells.

Exposure to arsenic trioxide take place of variety ways, for example, fuel, drinking water, pesticides, air, and food that is a threat for human health [8,16].

There are many contributions to causing many health issues, one, in particular, is cancer. The tap water that we drink contains chemicals that contribute to causing cancer. One specific chemical is DDT, scientifically known as dichlorodiphenyltrichloroethane, it is an odorless chemical that has no taste, that is used as an insecticide. In addition, the chemical is also used to fight against diseases. According to the Environmental Protection Agency (EPA), “DDT (dichloro-diphenyl-trichloroethane) was developed as the first of the modern synthetic insecticides in the 1940s. It was initially used with great effect to combat malaria, typhus, and the other insect-borne human diseases among both military and civilian populations” (EPA). Although

Carcinogens are known to cause debilitating health problems such as cancer when consumed by humans. The Ames test is used to detect carcinogens as an initial step that assists in further research. In this experiment, the water collected from local water bodies was tested using the Ames test to detect mutagenicity. The locations where samples were picked include the commercial canal and the residential lake. It was predicted that because of its commercial area, the canal would have a more significant amount of mutagens compared to the residential lake sample. The examples alongside a positive control of sodium azide and negative control of clean water were blended with a strain of Salmonella typhimurium separately. The Salmonella typhimurium cannot synthesize its amino acid, histidine. If those mutagens are available in the specimens, it changes and has the capacity to develop in an environment lacking histidine.

Inorganic arsenic is highly toxic and a significant public health threat throughout the world. Long-term exposure to arsenic through contaminated water can lead to arsenic poisoning and a variety of adverse health effects, including skin lesions, cancer, and respiratory and cardiovascular conditions. However, arsenic is highly abundant in the Earth’s crust and is naturally present across the world in the air, water, and soil. Arsenic integrates into the environment with natural processes including weathering reactions and volcanic activity, and through anthropogenic processes such as mining, fossil fuel combustion, and utilization of pesticides.

The chemical compounds of Aluminum usually appear in the trivalent state of the molecule (Al3+) (House et al. 2010). The human exposition to Aluminum occurs mainly through alimentation, inhalation; it can also occur through drinking water, cosmetics and medicaments. (Greger et al.,1992). The occupational exposures to this metal occurs in mining and processing, also in the fabrication of Al products. (JL, Lin et al., 1997). A big number of epidemiologic studies relates the content of Aluminum in the drinking water with the increasing of the