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What Is Quinapril?

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Quinapril
Chemical name (Quinapril):- [3S-[2[R*(R)],3R*]]-2-[2-[[1-Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2, 3,4-tetrahydro-3-isoquinolinecarboxylic acid monohydrochloride. [1]
Molecular formula:- C25H30N2O5•HCl
Active component:- Quinaprilat
Chemical name:- [2[R*(R*)],3R*]]-2-[2-[(1-Carboxy-3-phenylpropyl)amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid [1]
Drug Class:- Angiotensin-Converting Enzyme Inhibitor
STRUCTURES
In-Active (prodrug) Quinapril [2] Active [2] Quinaprilat

METHOD OF ACTIVATING [3,4]
Quinapril is a monoethyl ester which is hydrolysed in the liver after absorption to frame a dynamic metabolite, quinaprilat, which is a more intense angiotensin converting enzyme (ACE) inhibitor than the parent drug. Quinaprilat has a short disposal half-life yet a powerful tying fondness for ACE.
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