Zofran Lawsuit
Was your child born with a defect after you took Zofran (ondansetron)? You may be surprised to learn that the drug was never approved by the U.S. Food and Drug Administration (FDA) to treat morning sickness in pregnant women. In spite of this, drugmaker GlaxoSmithKline (GSK) marketed Zofran for this very purpose, prioritizing profits above the wellbeing of expectant mothers and their infants in a shocking display of negligence.
Since then, multiple reports of serious fetal injuries resulting from Zofran use have been brought forward. For illegally promoting the drug’s “off-label” usage, GSK paid a $2 billion settlement in a civil lawsuit in 2012. This settlement did not include payments for damages suffered due to the use of Zofran. As Zofran birth defect victims, you and your child may be entitled to compensation for medical costs, emotional distress, loss of income, and other damages.
The Wilshire
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Although the FDA approved the use of Zofran only for the treatment of nausea and vomiting in cancer patients, GSK promoted the drug to physicians as a viable treatment option for pregnant women experiencing severe nausea. This would later prove ill-advised.
Several medical studies published in recent years have linked Zofran to the increased occurrence of major birth defects:
• In August 2013, a group of researchers compared outcomes among nearly 900,000 women who took Zofran during pregnancy between 1997-2010. They found that Zofran was associated with a doubled risk of heart defects, contributing to a 30 percent increased risk of birth defects overall.
• In December 2013, Australian researchers linked the use of Zofran in the first trimester with a non-significant 20 percent increased risk of birth defects.
• In December 2014, a study was published in Reproductive Toxicology that indicated a doubled risk of septal heart defects in infants whose mothers took Zofran during early pregnancy from
not give because : fetal damge and congental malformation , life-thretening with drawl symptoms in a newporn also the drug can pass into breast milk
After reviewing the article it is clear that more needs to be done to create transparency in the study of drugs and public awareness. As a doctor in Canada Dr. Navindra has a right to access and study information so he can provide due diligence to his patients. If the study found that this drug was harmful to pregnant mothers,
Suboxone has not been tested to be safe in pregnant woman. Methadone has been used for over twenty years in welcoming drug and withdrawal free newborns in the world. (Satz, 2012).
Stimulants are considered as a drug and are commonly used today. The question is will use of stimulants while pregnant affect the infant. A pregnant woman can be prescribed stimulants (Antidepressants) because of them being depressed and stressed out about everything that is occurring in their life while pregnant, but what many people do not see is it going to affect the infant long-term. Most mothers want what is best for their child and they want to make sure that their child is going to have a healthy life as much as possible. Is it safe to take the antidepressants while pregnant and will there be any risk factors? There is mainly a biological and environmental that reflect a child’s senses and development.
Question/Prompt: Why are job analyses important in an organization? Describe the information that should be included in a job analysis as well as methods for collecting it. Also, explain the connection that exists among job analysis, job description, and job specifications.
The fetus is at greatest risk during the first trimester. This is the time when the cells differentiate and develop into limbs and organs. Drug use during this time poses a risk to organ development. The second and third trimesters involve mauration of the developing body parts. The risk of spontaneous abortion in the second trimester and of premature birth in the third are increased with drug use. Because the brain and nervous system are developing throughout the pregnancy, the nervous system is vulnerable to damage at any
Substance abuse has been a worldwide problem at all levels of society since the beginning of time. Attention has been made toward the use of legal and illegal substance by pregnant women over the past several decades. Almost all drugs are known to cross the placenta and have some effect on the fetus. According to the American Academy of Pediatrics (2013) the first studies of the effect of substances consumed by a pregnant women to the developing fetus were identified in the 1960’s of prenatal tobacco use. These studies opened the door to further research and studies. The effects of Alcohol and opiate use have been studied since the 1970’s (Jones, Smith, 1973) and the effects of a variety of other drugs have been studied since 1979 and early 1980’s (Flinnegan, 1979).
chemicals. Many women, who took diethylstilbestrol (DES) to prevent miscarriages, increased the risk for breat cancer in their children.
Many people might wonder why kids are born differently than what most consider “normal.” Multiple substances are effects that cause these fetus to develop wrong and not in usual routine that is normally seen in pregnancies. If a pregnant woman chose the wrong temptation and consumed substances that are known to cause damage and can be fatal to a baby, these mothers are making the worst mistake of taking the life of their own child away before the baby can experience what life is. Carrying a baby in the womb is one of the most heaviest challenges a woman can face and many females go wrong by falling into various temptations by not having enough information in pregnancies and going on with their daily lifestyle instead of learning about instant fetal deaths.
An abrupt cessation of opioids during pregnancy can lead to many severe complications, affecting both mother and fetus. Poor fetal outcomes may be seen due to this discontinuation of opioids such as an increased risk of intrauterine passage of meconium and neonatal aspiration, preterm labor and birth, fetal growth restriction, as well as fetal distress or demise (Keough & Fantasia, 2017). There is also an increased risk of placenta previa, placental abruption, premature rupture of membranes, and postpartum hemorrhage, all maternal high-risk factors (Shaw et al., 2016). Therefore, it is detrimental to educate woman of the child-bearing age of these dangers prior to their attempt to conceive.
In the late 1950s, the Thalidomide drug was used in Europe to treat morning sickness in pregnant women among other things. This study involved manufacturing company providing samples of this drug to physicians and compensating them to study the benefits and results of this drug. Although allegedly this drug did not cause any harm to the mother the fetus suffered severe damage as a result. There were thousands of children born with
The drugs that are used to treat neonates can be used multipurposely and often innovation drives creative uses of drugs to treat uncommon multifactorial complications (Allegaert & van den Anker, 2015). Knowledge of the drugs and their adverse effects is increasingly important when dosing a neonate. Due to their undeveloped body systems, in an event of an undesired reaction or drug error, the neonate would not be able to compensate and recover like the other patient groups may (Skene, Gupta, Flaherty, & Sherwood, 2012). Furthermore, this stresses the importance of being competent in drug calculations and being aware of the effect of medicines on this particularly vulnerable patient group (Stavroudis, Shore, Morlock, Hicks, Bundy, & Miller,
The public uses propaganda every day to form opinions of events. There are so many examples of propaganda that we see daily that it is hard to find the perfect example of how the public and propaganda form a relationship. After, thinking about it I realized that throughout my day I had fallen into propaganda many times throughout the day. For example, as I was grocery shopping I argued with my sister over what the best option was for the bread. We argued that the wheat was better because it was 70 calories a slice, gluten-free, along with multiple other advertisements on the front that suggested it was the best option. Of course, I fell into propaganda through these advertisements I began to form my opinion and believe this bread was best because
Most women are unaware of the risks associated with taking prescription medications while pregnant. Usually the fear
It did not require very much thought to narrow down the list of Graphic Design Disciplines. Of the twelve types of disciplines discussed, I can see myself working in the fields of Brand and Identity Design, Motion Graphics, and Advertising.