Wilsons Disease Research Paper

Huntington’s disease is a disease with symptoms that appear between the ages of 30 and 50. Symptoms include: the incapability to walk, difficulty in swallowing, contractions of the face, paranoia, and changes in personality to name a few. The disease can last up to 15 years, and it ultimately causes death. Purdy stated that this disease can be thought to be equal to any other impactful genetic disorder or disease. With that being said, Purdy declared that a disease like Huntington’s demonstrates why it is immoral for a mother to conceive when she knows that her child will later be prone to an early death or debilitating symptoms. Purdy states that parents that are risk for Huntington’s disease and other genetic diseases and disorders have a moral responsibility to not have children that will be affected with genetic diseases or disorders. Purdy again refers to the medical advancements that are present that will detect genetic diseases, defects, or disorders. Ultimately, Purdy believes that with the medical advancements that detect genetic diseases, parents should not have children that will be prone to genetic

Metabolism and genetics also participate in cirrhosis for example abnormal collection of iron (hemochromatosis) or copper (Wilson's disease) in the liver causing injury, scarring and cirrhosis. Further cause of cirrhosis is the Autoimmune chronic active hepatitis that happens when the immune system attacks the liver and causes inflammation, damage, and cirrhosis. Drugs and chemicals also cause injury of the liver.

The first disease Moalem discusses, hemochromatosis, is a hereditary disorder that he himself lives with. It causes excess iron buildup throughout the body, damaging “the joints, the major organs, and overall body chemistry” (p. 13). Hemochromatosis can lead to “liver failure, heart failure, diabetes, arthritis, infertility, psychiatric disorders[, ...] cancer” (p. 13) and, in the end, death. Although it is more common in some communities than others, today the low-penetrance disease only manifests in 1 in 200 people.

Sickle cell: One of the first inherited diseases to be unraveled at the level of DNA was sickle-cell anemia which is defined as abnormal, crescent-shaped red blood cells that results from a single change in the amino acid sequence of the cell's hemoglobin, which causes the cell to contort, especially under low-oxygen conditions. (medical dictionary, 2017) Also, called drepanocyte, meniscocyte. Also, this blood disorder mostly affects Africans and natives of the Mediterranean region are those who are affected by malaria. A single mutation in the gene for the blood protein hemoglobin can affect its ability to transport oxygen around the body. People who inherit two copies of the same mutation, one from each parent, have severe symptoms.

A 13-year-old girl named Savana Redding's math class at Safford Middle School on October day in 2003. The assistant principal of the school, Kerry Wilson, came into the room and asked Savana to go to his office. Savana stated that none of the items in the planner belonged to her. Wilson then showed Savana four white prescription-strength ibuprofen 400-mg pills, and one over-the-counter blue naproxen 200-mg pill, all used for pain and inflammation but banned under school rules without advance permission. He asked Savana if she knew anything about the pills. Savana answered that she did not. Wilson then told Savana that he had received a report that she was giving these pills to fellow students; Savana denied it and agreed to let Wilson

Sergeant #6020 has enticed us with his persuasive personality and his manipulative mind set. Engulfed in a world of lies, the reality of a true crime investigation takes place in a small town of Saskatchewan. Sgt. John Wilson’s life begins unraveling right in front of your eyes. Lois Simmie captures a tragic story of love, lies, and the ultimate betrayal.

The first disease Moalem discusses, hemochromatosis, is a hereditary disorder that he himself lives with. It causes excess iron buildup throughout the body, damaging “the joints, the major organs, and overall body chemistry” (p. 13). Hemochromatosis can cause conditions such as “liver failure, heart failure, diabetes, arthritis,

Iron is an important nutrient because it helps carry oxygen in the hemoglobin in red blood cells around the human body. When a healthy iron supply is reached, the body immediately stops absorbing the nutrient, and just lets it past through the digestive system. However, people with hemochromatosis absorb all the iron from the food consumed, past healthy levels.­­­­­­ All the extra iron spreads throughout the body, and unevitably causes great damage to major organs and almost all other parts of the body. According to Survival of the Sickest, "hemochromatosis can lead to liver failure, heart failure, diabetes, arthritis, infertility, psychiatric disorders,... cancer," and other diseases if left untreated (Maulem

There are many known genetic diseases in the world. There are different types such as chromosomal and monogenic. Chromosomal disorders are when someone has too many or not as many chromosome as they are suppose to have (46 total chromosomes). Chromosomal disorders can also manifest when there are structural abnormalities. Monogenic disorders are an inherited medical condition caused by a DNA abnormalities. These diseases occur all throughout the world today. Depending on what region of the world you are in depends on what the most common ones are. Cystic Fibrosis has become the most common lethal genetic disease in the United States as of 1999. Although there are treatments available, there is not a known cure, and the effects remain burdensome

In his novel Puddn'head Wilson, Mark Twain utilizes supremacist discourse and belief system to look at bondage's outcomes and make a request for change for African Americans. Rather than mocking the black race, Twain is pushing for social value by showing how far blacks have fallen. He expected to exhibit the points of view of that local town of Dawson's Landing in Missouri, at the edge of the Mississippi River. Twain's novel can seem like a problem at first, since it is a story about enslavement made practically forty years after the completion of the Civil War. Despite the way that a black man never again expected to fear being sold "down the stream" as Roxy and Chambers do, simply because of the complexion of their skin (Watson, 2011).

poor health that he had to deal with since his childhood. Wilson always had a

A genetic disorder is an a disease or condition caused by one or more abnormalities in the genome. Genetic disorders are an inherited medical condition, which are caused by a DNA abnormality. “Noonan Syndrome is a genetic disorder, it prevents normal development in different parts of the body (Mayo, 2016).” There are several different abnormalities caused by Noonan Syndrome that can affect people. Noonan Syndrome is a genetic disorder which a means it can be passed through parents to their children.

It is essential to treat Wilson's disease. The earlier treatment is started, the better the chance of preventing long-term permanent damage to the liver or brain.

Some foods, such as chocolate, liver, nuts, mushrooms, and shellfish contain high levels of copper. Treatment for Wilson’s Disease includes to simply avoid these foods and to make such dietary changes (Ala et. al, 2007). This form of therapy is rarely used alone and accompanied by the use of medication. For patients unable to adjust to the medication or have presented severe deteriorating hepatic symptoms of Wilson’s Disease before other treatment was ever possible, a surgical orthotopic liver transplantation is often carried out if they meet the criteria as a suitable candidate. According to several studies, liver transplantation of this nature presents a phenotypic cure through a partial correction of the metabolic defect (Bellary et. al, 1995). Therefore, the survival rate for Wilson’s Disease patients who successfully undergo an orthotopic liver transplantation have a long-term survival rate of approximately eighty percent (Bellary et. al,

About 1 in 30,000 people have Wilson disease. Wilson’s disease happens equally in men, women and children. Most people with Wilson’s disease are born with it. Wilson’s disease is more common in Eastern Europe. Wilson’s disease symptoms typically appears in people under 23 years old. In children, it is rarely diagnosed before the age of 4 years. Younger children rarely show any symptoms. The increased frequency in certain countries is due to higher rates of consanguinity.