ZIKV Vaccination

First isolated from a rhesus monkey in Uganda, the Zika virus (ZIK V) did not pose a serious global threat until recent outbreaks in 2007 on Yap Island in Micronesia and the current outbreak which began in 2013 in the French Polynesia. And, although the virus is transmitted via infected mosquitoes, studies indicate that the disease potentially can be transmitted sexually (Musso, D., Roche, C., Robin, E., Nhan, T., Teissier, A., and

Zika virus was discovered by scientists in the Zika rainforest in a remote part of Uganda in 1947, in the serum of an infected rheseus monkey. With five thousand two hundred thirty- four known cases of the infectious virus documented in the United States. There is currently no vaccination for the flu like virus. The chief concern of the healthcare administration is to continue to take preventive measures to prevent contracting the virus. Within the same flavivirus family

Ferguson --- based on the Center for Disease Control and Prevention website --- the vaccines are meant to prevent any occurrence of the shingles, so it may be unlikely for any shingles to appear during 5 years of its effectiveness. They had also mentioned how one is still able to receive the vaccine even after having shingles, but it’s suggested to ask ones healthcare provider first. As for why vaccines are approved for adults over 50 ---- based on U.S. Food & Drugs question and answer, they mention how they conduct a study on people ageing from 50 and older and see what effectiveness of both zostavax and placebo have on shingles. Research shows that the vaccine inside the people ages 50-69 were more effective than those aging form 70 -80.

Vaccinations are considered to be the greatest health development of the 20th century. Because of advancements in medicine, vaccinations are becoming a widespread medium in the prevention of disease. They have provided the eradication and immunity to many deadly diseases such as smallpox, polio and rubella. Although there is no law that mandates the vaccination of children, they are necessary to prevent the infliction of disease and harm. By making the decision to vaccinate their children, a parent has the potential to save their lives.

This article focuses on the outbreak of the Zika virus, which has recently begun spreading across the world with an emphasis on Latin American countries Brazil and Colombia. There are currently over 26,000 people who have been confirmed as infected with the virus in Colombia alone and this number is expected to rise dramatically to about 600,000 within the coming months considering the location and altitude of the countries and the frequency of their carrier mosquito. The virus has no vaccine yet; all prevention methods are focused on controlling the mosquitos spreading the disease by promoting proper sanitation regarding dirty water storage and accumulated trash. Among the people infected is 16-year-old Angie Paola Castro, one of 3,177 women

Providing immunization to human beings by vaccination is one of the greatest achievements in the public health field. It is responsible for a significant increase in the quality of life for children in 21st century compared to the previous era. Childhood vaccination is usually provided at a young age as a routine service in specific clinics or other health facilities. Children are required to receive specific scheduled vaccinations shortly after they are born. Vaccinations can also be received in specific public campaigns where a specialized trained team provide vaccines to people in a targeted area for a few days or even weeks. The purpose of these is to provide maximum protection to the population in a short amount of time. Despite this,

The start of the video explains the origin of the propagation of the Zika virus, which uses the Aedes mosquito as a host, to aid in the dispersion of the virus by method of biting. Once the person has been bitten by the mosquito and contract Zika, the virus can continue to disseminate through sexual contact or from a pregnant woman to her fetus. The Center for Disease Control and Prevention (CDC) arrived to an important conclusion, Zika virus causes many malformation

A particular stain of the Zika Virus, PRVABC59, has recently become an epidemic in South America and the Pacific¹, and in the last month has spread to Florida. PRVABC59 is a Flavivirus, ssRNA(+), is spread by Aedes Aegypti and Aedes Albopictus mosquitoes and is capable of spreading from mother to unborn child during pregnancy. Although the Zika virus normally doesn’t cause severe symptoms, further complications arise if a fetus is infected, as stated by the World Health Organization “There is scientific consensus that Zika virus is a cause of microcephaly and Guillain-Barré syndrome”. Before more research can be done to develop a vaccine or treatment, a specific primary antibody must be created as a tool for further research about the function of the ten proteins in the Zika genome. This project worked on nine of these proteins in ten parts. Two structural proteins, capsid and pre-membrane protein, and the seven non-structural proteins, with NS5 being split into two pieces due to its size and toxicity. A previous method of protein production and purification2 was followed to create these antibodies. This method of protein production and purification should lead to a primary antibody specific to recombinant proteins of the PRVABC59 strain of Zika virus, which is a necessary tool for further research into the PRVABC59 strain.

April 2015, small but deadly outbreaks began in Brazil, South America. Hundreds of Brazilian women infected by the Zika virus, endanger their unborn children to develop a form of brain damage called, Microcephaly. In the early months of 2016, South America’s CDCP (Centers for Disease Control and Prevention) announced the Zika virus has taken full effect, and called for a state of emergency. Researchers today, study the effects of the Zika virus, where it comes/evolved from, and if there is a cure.

Herd immunity is a type of immunity that happens when a large quantity of vaccinated people generate a measure of protection for people who have not developed immunity.

The Zika virus is very well known around the world as a mosquito carried virus that may cause birth defects to unborn children if pregnant women are infected. Since the Zika virus started spreading widely sometime in 2013, there has been many efforts to regulate the virus with a vaccine to prevent any harm to pregnant women and their unborn children. In the article, “Considerations for Developing a Zika Virus” written by Hilary Marston, provides useful information about what should be considered when developing a Zika vaccine in order to be successful and to eliminate any risk to pregnant women. Marston has stated her idea that, “An efficient development pathway must be delineated, including the optimal ways to evaluate the safety, immunogenicity, and effectiveness of vaccine candidates for intended target populations.” When creating a vaccine, Marston states that the

Researchers found the Zika virus is a member of the Flaviridae family and is transmitted to humans by, mosquitoes. Although these research results are promising, it is difficult to determine whether this experiment really did ZIKV virus is a members of the Flaviridiae family or different family. Was the experiment of the ZIKV conduct appropriately to all animal? And although this research promising, results for the most flaviuvirus family. Interestingly, the virus was also detected in testicles of infected mice. We have no idea whether these result are applicable to another types of virus. So this article is miss leading and this conclusion does not necessary apply to all virus.

Zika virus (ZIKV), a Flaviviridae family member is an arbovirus transmitted to humans by mosquitoes of the species Aedes aegypti. ZIKV epidemic over the past few years has implicated a rapid incline in neonatal microcephaly and Guillain Barre syndrome has become an immense global health issue. Like other Flavivirus, ZIKV has an enveloped, single positive sense RNA genome. The ZIKV glycosylated non- structural protein-1 (NS1) is known to be the main conserved feature among flavivirus, which interferes with host molecules and is vital in viral replication as well host immune modulation and pathogenesis. However, compared to typical flaviviruses such as dengue virus (DENV) and West Nile virus ,ZIKV NS1 demonstrates independent coding sequence

When watching a science fiction movie on the big screen about the end of the world being brought on to humanity via disease or virus, it is easy to take it lightly and brush it off as another Hollywood concoction. There is some truth and seriousness attached to the fabricated plots that are served to us though these movies. Recently there has been news of contagious breakouts such as Ebola and Methicillin-resistant Staphylococcus aureus (MRSA) that affect the populations in hospitals and particular locations of the world. There is an international concern in the Zika virus by the recent outbreak at different countries. Regardless of their place of origin they travel quickly and respect no boundaries or regions. These scenarios if not handled properly can quickly compromise the health of the general population and result in the death of otherwise healthy individuals. A major problem we are all facing is the misinformation and lack of education when pertaining to matters of newly emerging viruses and diseases. People need to show more interest in being informed about newly emerging viruses and diseases that can not only cause harm but death. In this paper, I plan to discuss the complex issues involved in the emergence of the Zika virus and will aim to provide information about how it is diagnosed and what the treatment options are for those exposed. My hope is that the lessons learned from distinct countries who are currently experiencing the outbreak can provide valuable

Protecting a child is what every mother strives for, but they can’t always prevent everything. Vaccinations are the help to a mother 's struggle with sick kids. Vaccines not only save a mother from a long day at home but they prevent crazy sick days. Control center of disease states that ; “Before vaccines many