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Zebrafish: A Biological Model

Satisfactory Essays
Owing to the optical transparency of the larvae, evolutionary similarity to humans, and large numbers of animals that can be employed in experiments, Zebrafish are a suitable model for studying the development and progression of glioblastoma. Glioblastoma multiforme is the most common malignant primary brain cancer with a median survival of 15 months after an aggressive treatment. Glioblastoma evade recognition and destruction from the immune system through changes in the biochemistry in the tumour vicinity. Moreover, studies until now recognize that direct interactions with cells from the immune system, such as microglia/macrophages and neutrophils promote cancer growth. The dynamics of tumour-immune-system-cells can be observed observed in
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