Zika Virus Lyme Disease Pertussis
Disease is limited to humans? (no animal reservoirs) Yes No, there are animal reservoirs Yes
Limited persistence in the environment? Yes Yes Yes, it is a couple of days.
Absence of long-term carrier state? Yes Yes No, the virus can live in an asymptomatic individual and be passed to others.
Long-term immunity results from infection? Yes No No, immunity from natural infection and vaccination wears off over time.
Vaccination confers long-term immunity? There is currently no vaccination. There is currently no vaccination No
Herd immunity prevents perpetuation of an epidemic? Herd immunity cannot occur through vaccination. However since the same person cannot be infected twice, Herd immunity may occur once there