. Males have hemophilia when they are hemizygous fora nonfunctional recessive mutant allele of the X-linkedgene for clotting factor VIII. Factor VIII is normallysecreted into the blood serum by cells in the bonemarrow (and other specialized cells) that produce it.a. Do you think that females heterozygous for thehemophilia disease allele could have hemophiliain some parts of their bodies and not others?b. If such a female carrier of hemophilia suffered acut, would her blood coagulate (form clots) faster,slower, or in about the same time as that of an individual homozygous for a normal allele of the factorVIII gene? Would the rate of clotting vary significantly among heterozygous females?
. Males have hemophilia when they are hemizygous for
a nonfunctional recessive mutant allele of the X-linked
gene for clotting factor VIII. Factor VIII is normally
secreted into the blood serum by cells in the bone
marrow (and other specialized cells) that produce it.
a. Do you think that females heterozygous for the
hemophilia disease allele could have hemophilia
in some parts of their bodies and not others?
b. If such a female carrier of hemophilia suffered a
cut, would her blood coagulate (form clots) faster,
slower, or in about the same time as that of an individual homozygous for a normal allele of the factor
VIII gene? Would the rate of clotting vary significantly among heterozygous females?
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