. The human genome contains about 3 billion basepairs. During the first cell division after fertilizationof a human embryo, S phase is approximately threehours long. Assuming an average DNA polymeraserate of 50 nucleotides/second over the entire S phase,what is the minimum number of origins of replicationyou would expect to find in the human genome?

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter28: Dna Metabolism: Replication, Recombination, And Repair
Section: Chapter Questions
Problem 8P: Human Genome Replication Rate Assume DNA replication proceeds at a rate of 100 base pairs per second...
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. The human genome contains about 3 billion base
pairs. During the first cell division after fertilization
of a human embryo, S phase is approximately three
hours long. Assuming an average DNA polymerase
rate of 50 nucleotides/second over the entire S phase,
what is the minimum number of origins of replication
you would expect to find in the human genome?

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