1. There are two metabolic routes for the conversion of oxaloacetate to phosphoenolpyruvate (PEP). What factors likely indicate which route is used? Do the two routes have different requirements for cellular energy (e.g. ATP)? 2. Compare the export of glucose from hepatocytes to the import into hepatocytes. 3. Would you expect anaplerotic reactions to be active in the postprandial hepatocyte? Why?

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter22: Gluconeogenesis, Glycogen Metabolism, And The Pentose Phosphate Pathway
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1. There are two metabolic routes for the conversion of oxaloacetate to
phosphoenolpyruvate (PEP). What factors
likely indicate which route is used? Do the
two routes have different requirements for cellular energy (e.g. ATP)?
2. Compare the export of glucose from hepatocytes to the import into hepatocytes.
3. Would you expect anaplerotic reactions to be active
in the postprandial hepatocyte?
Why?
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