1.) What is one type of cell that CANNOT arise from the differentiation of a mesenchymal stem cell? A. A neuron B. A muscle cell C. An egg cell D. A bone cell 2. there is the statement: "Both stem cells and specialized cells have all the same genes. They differ in the regulation of those genes and express very different sets of genes ". Which one of the following explanations best accounts for this difference in stem cell and specialized cell gene expression? A. Stem cells and specialized cells have different activators and repressors that affect transcription B. Stem cells and specialized cells have different promoter sequences for their genes, thus affecting transcription C. Stem cells and specialized cells have different ribosomes that affect translation D. Stem cells and specialized cells use different start codons on mRNAs, thus affecting translation

1.) What is one type of cell that CANNOT arise from the differentiation of a mesenchymal stem cell? A. A neuron B. A muscle cell C. An egg cell D. A bone cell 2. there is the statement: "Both stem cells and specialized cells have all the same genes. They differ in the regulation of those genes and express very different sets of genes ". Which one of the following explanations best accounts for this difference in stem cell and specialized cell gene expression? A. Stem cells and specialized cells have different activators and repressors that affect transcription B. Stem cells and specialized cells have different promoter sequences for their genes, thus affecting transcription C. Stem cells and specialized cells have different ribosomes that affect translation D. Stem cells and specialized cells use different start codons on mRNAs, thus affecting translation

Biology (MindTap Course List)

11th Edition

ISBN:9781337392938

Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Chapter17: Developmental Genetics

Section: Chapter Questions

Problem 2TYU

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Why is it easier to manipulate embryonic stem cells to differentiate into various tissues than it is to manipulate a typical adult cell? a. As cells develop, signaling pathways can cause some genes to be turned off during development. b. Adult cells have different DNA content than do embryonic stem cells. c. Emybronic stem cells pose less of a threat for organ rejection as do an individual s own adult cells. d. It is no easier to manipulate emybronic stem cells to differentiate into various tissues than it is to manipulate a typical adult cell.
I am confused about how stem cell transplants works. If you put a semi differentiated tadpole nucleus in a denucleated egg cell, it’ll develop into a fully formed tadpole, but if you put a fully differentiated tadpole nucleus, it won’t (because the genes have already been expressed in a way where the cytoplasmic determinants cannot operate to the fullest). Then how come in stem cell transplants, you use adult nucleuses that are already developed and transplant them into the denucleated egg cells?
Which of the following best describes the concept of cell differentiation during the development of a multicellular organism? A. During development, all of the genes in the embryo's cells are expressed at first, but fewer and fewer are expressed as time proceeds. B. During development, different sets of genes are deleted from different cell types so that at the end of development, each cell has only the genes it needs. C. During development, different cells become specialized to have different phenotypes even though they all originated from the same cell. ..
The term differentiation refers to (a) the loss of genes from cells. (b) the acquisition of new functional capabilities by cells. (c) the production of functionally specialized cells. (d) the division of genes among different types of cells.
What is differentiation? A. When a cell switches from its original purpose B. The process of multiplying the cells in the body C. The process by which cells become specialized in their form to aid in their function D. How cells grow once their place in the body has been decided
With regard to cancer cells, which of the following statementsare true?A. Cancer cells are clonal, which means they are derived from asingle mutant cell.B. To become cancerous, cells usually accumulate multiplegenetic changes that eventually result in uncontrolledgrowth.C. Most cancers are caused by oncogenic viruses.D. Cancer cells have lost the ability to properly regulate celldivision.
In other words, the master regulator initiates a program of gene expression that narrow the potential fates of the precursor's cells’ descendants to the type of cells that participate in the organ’s function. Question: Once a master regulator gene is turned on in some cells and not in others, how do cells “remember” that pattern through all the cell division that occur to form a specific organ?
Explain the difference between asymmetric and symmetric cell division. When the pool of stem cells for a particular tissue needs to expand, which of these two cell division mechanisms is utilized?
The p53 gene was discovered in 1979, but it was not clear whether the gene functioned as an oncogene or a tumor-suppressor gene. Several years later, researchers showed that both p53 alleles are inactivated in some mouse cancers. This evidence suggests A. the p53 gene is an oncogene because inactivated alleles would produce mutated signal transduction proteins that would result in stimulating cell division. B. the p53 gene is an oncogene because the cell would overproduce transcription factors to compensate for the inactive alleles, resulting in increased cell division. C. the p53 gene is a tumor-suppressor gene because inactivated alleles indicate a loss of protein function which allowed the cancer to develop D. the p53 gene is a tumor-suppressor gene because the cell would produce too few transcription factors for gene activation, resulting in decreased cell division.
If you determined the Muv-causing mutation functioned in the primary cell lineages, how could you determine if the gene works in upstream or downstream of let-60 in the differentiation pathway. Tell me specifically what read out (phenotype) you’re using to determine the order, that is, what are the experiments and what specifically what are you observing/counting?
Describe how Ras and p53 can alter the simplified genetic pathway controlling cell division shown below. For each of the two genes, would uncontrolled cell division result from a loss-of-function or a gain-of-function mutation? growth factors - receptors - cyclins - cyclin-dependent kinases - cell division
1. a)Proteins that stimulate/promote progression through the cell cycle are encoded by (oncogenes or tumor suppressor genes). Boldface one. b)Proteins that inhibit progression through the cell cycle are encoded by (oncogenes or tumor suppressor genes). Boldface one. c)What is the difference between a proto-oncogene and an oncogene? d)To cause cancer, proto-oncogenes require (1 or 2)allele(s) to be mutated and therefore are considered (dominant or recessive). The mutation results in a (loss or gain) of function. For each underlined pair, boldface one. e)To cause cancer, tumor suppressor genes require (1 or 2)allele(s) to be mutated and therefore are considered (dominant or recessive). The mutation results in a (loss or gain) of function. For each underlined pair, boldface one.

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	A.	Stem cells and specialized cells have different activators and repressors that affect transcription
	B.	Stem cells and specialized cells have different promoter sequences for their genes, thus affecting transcription
	C.	Stem cells and specialized cells have different ribosomes that affect translation
	D.	Stem cells and specialized cells use different start codons on mRNAs, thus affecting translation