Question
Asked Dec 12, 2019
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3) You have identified an interesting mutant in gene P. Using a Punnett square, demonstrate the cross you perform to determine if it is a dominant or recessive mutation compared to the WT gene P allele. Write the expected ratios for either scenario. 

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Expert Answer

Step 1

Genes are the functional unit of heredity. Genes are made up of DNA and they carry coded genetic information, which is essential for every trait of the organism. Mutations are sudden heritable changes that alter the nucleotide sequence of the DNA, thereby affecting the genome of the organism and affecting its heritable traits.

Step 2

Test cross is used to determine the zygosity of the mutant allele. Dominant alleles can be either homozygous (having identical alleles) or heterozygous (having non identical alleles). Test cross involves crossing of an individual that is phenotypically recessive with the organism, whose genotype is unknown. There occur different ratios, which is essential to find out the zygozity of the mutant allele.

 

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Punnett square of recessive allele and homozygous dominant mutant allele. Pp Pp | Pp Pp

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