30.13 A stent is used to "prop up" a clogged artery to allow blood to pass through it. But stents can also be loaded with drugs to facilitate the timed release of the drug into the body, especially if the drug is not very soluble in body fluids. Consider the very simple stent design as illustrated below. The pole of the stent, which is 0.2 cm in diameter and 1.0 cm in length, is coated with the anticancer drug Taxol. The thickness of the coating is 0.01 cm and 5.0 mg total Taxol is loaded. Blood flows through the 1.0 cm diameter cylindrical blood vessel at a volumetric flow rate of 10.0 cm /s. Taxol is not very soluble in aqueous environments; the maximum solubility of Taxol in blood is 2.5 × 10¬4 mg/cm³. The viscosity of blood is 0.040 g/cm - s and its density is 1.05 g/cm³. Blood is a complex fluid but you may assume that its average molecular weight is close to that of liquid water. The molecular diffusion coefficient of Taxol in fluid blood is DAB = 1.0 × 10-6 cm²/s.

30.13 A stent is used to "prop up" a clogged artery to allow blood to pass through it. But stents can also be loaded with drugs to facilitate the timed release of the drug into the body, especially if the drug is not very soluble in body fluids. Consider the very simple stent design as illustrated below. The pole of the stent, which is 0.2 cm in diameter and 1.0 cm in length, is coated with the anticancer drug Taxol. The thickness of the coating is 0.01 cm and 5.0 mg total Taxol is loaded. Blood flows through the 1.0 cm diameter cylindrical blood vessel at a volumetric flow rate of 10.0 cm /s. Taxol is not very soluble in aqueous environments; the maximum solubility of Taxol in blood is 2.5 × 10¬4 mg/cm³. The viscosity of blood is 0.040 g/cm - s and its density is 1.05 g/cm³. Blood is a complex fluid but you may assume that its average molecular weight is close to that of liquid water. The molecular diffusion coefficient of Taxol in fluid blood is DAB = 1.0 × 10-6 cm²/s.

Principles of Heat Transfer (Activate Learning with these NEW titles from Engineering!)

8th Edition

ISBN:9781305387102

Author:Kreith, Frank; Manglik, Raj M.

Publisher:Kreith, Frank; Manglik, Raj M.

Chapter8: Natural Convection

Section: Chapter Questions

Problem 8.47P

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