# 32CHAPTER 3 Quantifying the Extent ofTABLETABLE 3-10 Alcohol Use and Outcome of PregnancyDelivered FullTermMiscarriage4Chole14Heavy alcohol usemeNo heavy alcohol4636PlacuseఈTABLE 3-11 Incident Coronary Artery Diseaseby TreatmentNumber withNumber ofCoronary ArteryParticipantsDiseaseCholesterolmedication40028Placebo4404004270the first trimester of pregnancy and miscarriage. Fiftywomen who suffered miscarriage are enrolled, alongwith 50 who delivered full-term. Each participant'suse of alcohol during pregnancy is ascertained.Heavy drinking is defined as four or more drinks onone occasion. The data are shown in Table 3-10.a. Compute the odds of miscarriage in women withheavy alcohol use during pregnancyb. Compute the odds of miscarriage in women withno heavy alcohol use during pregnancy. TABLE 3-12 Total Follow-Up Time by TreatmentNumber withTotal Follow-Up(years)CoronaryArtery DiseaseCholesterol345128medication298442Placeboc. Which measure is more appropriate in thisdesign, the relative risk or odds ratio? Justifybriefly.5In the study described in Problem 4, some patientswere not followed for a total of 10 years. Some sufferedrants (i e develonedco

Question

a. Compute the relative risk of coronary artery disease in patients receiving the new cholesterol medication as compared to those receiving a placebo.

b. Compute the odds ratio of coronary artery disease in patients receiving the new cholesterol medication as compared to those receiving a placebo.

c. Which measure is more appropriate in this design, the relative risk or odds ratio? Justify briefly.

Step 1

Amongst the provided tables, table 3-11 is used to answer the asked questions.

a) The relative risk of coronary artery disease in patients receiving the new cholesterol medication as compared to those receiving a placebo can be obtained as:

Step 2

b) The odd ratio of coronary artery disease in patients receiving the new choleste...

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