4. A clinical trial is run to investigate the effectiveness of an experimental drug in reducing pretermdelivery to a drug considered standard care and to a placebo. Pregnant women are enrolled andrandomly assigned to receive either the experimental drug, the standard drug or a placebo. Women arefollowed through delivery and classified as delivering preterm (37 weeks) or not. The data are shownbelowExperimental DrugStandard DrugPreterm DeliveryPlaceboYes172335No837765Is there a statistically significant difference in the proportions of women delivering preterm among thethree treatment groups? Run the test at a 5% level of significance

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Asked Dec 4, 2019
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Question 4

4. A clinical trial is run to investigate the effectiveness of an experimental drug in reducing preterm
delivery to a drug considered standard care and to a placebo. Pregnant women are enrolled and
randomly assigned to receive either the experimental drug, the standard drug or a placebo. Women are
followed through delivery and classified as delivering preterm (37 weeks) or not. The data are shown
below
Experimental Drug
Standard Drug
Preterm Delivery
Placebo
Yes
17
23
35
No
83
77
65
Is there a statistically significant difference in the proportions of women delivering preterm among the
three treatment groups? Run the test at a 5% level of significance
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4. A clinical trial is run to investigate the effectiveness of an experimental drug in reducing preterm delivery to a drug considered standard care and to a placebo. Pregnant women are enrolled and randomly assigned to receive either the experimental drug, the standard drug or a placebo. Women are followed through delivery and classified as delivering preterm (37 weeks) or not. The data are shown below Experimental Drug Standard Drug Preterm Delivery Placebo Yes 17 23 35 No 83 77 65 Is there a statistically significant difference in the proportions of women delivering preterm among the three treatment groups? Run the test at a 5% level of significance

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Step 1

Null Hypothesis:

There is no statistically significant difference in the proportions of women delivering preterm among the three treatment groups.

Alternative Hypothesis:

There is statistically significant difference in the proportions of women delivering preterm among the three treatment groups.

Procedure for calculating chi-square test statistic using MegaStat:

  • Go to MegaStat > Chi-square/Crosstab > Contingen...
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Chi-square Contingency Table Test for Independence Experimental Drug Standard Drug Placebo Total Observed Expected (0-E/E Observed Yes 17 25.00 23 25.00 0.16 35 25.00 4.00 75 75.00 2.56 83 6.72 225 No 77 65 225.00 2.24 Expected (O- E/E Observed Expected (O-E/E 75.00 0.85 75.00 0.05 75.00 1.33 Total 100 100 100 100.00 5.33 300 300.00 8.96 100.00 3.41 100.00 0.21 8.96 chi-square 2 df 0113 p-value

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