4. A woman with skin cancer gets a biopsy of one of her tumors taken, and a sample of her blood. DNA is prepared from both samples and the sequence of the coding region of the p53 gene is compared. The following difference is found: Blood: 5'-ATGCAAGTTCTA Tumor: 5'-ATGCAAGTCTA This is an example of: А. Silent substitution Missense substitution Nonsense substitution В. С. D. Frameshift E. None of the above

Q: 2. In your own words, describe two different reasons why a eukaryotic cell may need to control gene…

A: gene expression is a process to regulate the production of active gene to produce the proteins to…

Q: 1. Why do you think SNPS are more commonly found in intergenic regions ? a.Because intergenic…

A: Single nucleotide polymorphism (SNP) is the change in the single nucleotide through addition or…

Q: 5. Assume that you are trying to do a gel mobility shift experiment using a normal set of Trp genes.…

A: The gel mobility shift assay is a biochemistry technique used to detect protein complexes with DNA.…

Q: 1. a)What would happen if the aminoacyl tRNA synthetase responsible for charging alanine tRNAs also…

A: The polymerization of amino acids according to the codons on mRNA to form proteins is known as…

Q: 1. Since 1978, scientists used a specific biotechnology to produce a medicine used to treat…

A: Technology used: Recombinanant DNA.                 technology. The technology used to make DNA from…

Q: 4. Some transposases use extensive DNA replication to leave one copy of the element behind in a…

A: Trnasposases are the enzymes that identify the inverse terminal repeat sequences within the DNA and…

Q: 2. The following schematic shows the chromosomal location of Gene 1 and Gene 2. The corresponding…

A: g)It will not be same. The direction of transcription is always determined by the location of the…

Q: 4. Assume that a new low-calorie sweetener is developed. The structure is novel and is tested with…

A: Any product that is intended for human consumption requires prior approval and usage recommendation…

Q: 15. The CRISPR/Cas9 system provides a form of adaptive immunity in bacteria. We discussed in class…

A: The correct option is DThe CRISPR/Cas9 system is a bacterial immune system to provide protection…

Q: Given that a faulty ribosomal protein is the culprit and causes DBA, discuss the possible role of…

A: Diamond Blackfan anemia is caused by mutations in ribosomal protein genes in about 80-85% of those…

Q: 14. Antithrombin is a drug that is approved by the U.S. Food and Drug Administration (FDA) to treat…

A: Blood is a fluid connective tissue which plays an important role in the transport of nutrients and…

Q: 5. The downstream process for a recombinant protein begins with 100 liters of clarified lysate. At…

A: Protein purification is series of processes to isolate one or few proteins from a complex mixture of…

Q: 1. What is mutation? Explain the random and site-directed mutagenesis methods .Which one is…

A: Q1 a mutation is change in the sequence of the DNA or something which alters the genetic sequence of…

Q: .What type of mutation is seen here? WT:                       5′-AUG GCU AGA GUU GAA  AAA-3′…

A: Note - Since you have asked multiple questions, we will solve the first question for you. If you…

Q: The two factors that bind directly to the DNA at Pacific sequences are TFIID and TFIIB- in general…

A: It is found in the eukaryotic transcription processing system.

Q: )A scientist compares the sequence of a disease gene and a healthy gene and finds that these two…

A: The gene is the unit of heredity that is carried out from the parents to the offspring. This…

Q: All of the following are beneficial effects of mutation, EXCEPT: * a. basis for skeletal disease…

A: Mutation: Any alteration in the gentif material of an organism is termed a mutation. Mutations can…

Q: 6. Why do you think the Ames test is preferable to the use of animal models to screen chemical…

A: Ames test is used to find whether a given chemical causes mutation in the DNA in the animal models.…

Q: 4. The bars in the following sequence indicate the breakpoints of a deletion.…

A: The given sequence has bars indicating the breakpoint of a deletion means we are going to delete the…

Q: 1. Below is the base sequence of protein for normal hemoglobin and the base sequence for the sickle…

A: 1. Below is the base sequence of protein for normal hemoglobin and the base sequence for the sickle…

Q: 17.Given that ATG indicates the start of a given gene, the mutation that causes 5'- ATGCTTCCCGGA…

A: The term "mutation" refers to changes in DNA sequences that arise unexpectedly. The mutation happens…

Q: 1. After exposure to a mutagen an A-T base pairing becomes T-A in the daughter cell. This is an…

A: Please note, keeping with the site regulations and in order to provide accurate and detailed…

Q: 3. You are investigating an abnormal eukaryotic cell line that makes mRNAs much longer than the…

A: mRNAs are single-stranded RNA molecules that are complementary to one of the DNA strands of a gene.…

Q: 1. What is the role of salt and dishwashing liquid in the extraction/isolation of DNA from yeast and…

A: "DNA extraction  or DNA isolation" is a procedure or a method wherein  DNA is purified by physical…

Q: Briefly explain the principle behind the following techniques: (a) ion-exchange chromatography (b)…

A: Since you have posted a question with multiple sub-parts, we will solve the first three subparts for…

Q: 1. What happen to the mutated sequence in the coding region of MT-ATP6 in Leigh's syndrome. Does it…

A: Leigh's syndrome is a rare neurogenetic disorder that affects the central nervous system. The…

Q: 1. Methylation of DNA and acetylation of histones are inversely correlated. II. Methylation and…

A: The main distinction among DNA methylation and histone acetylation is that DNA methylation leads in…

Q: C. Two mutations are known in the population, one shaded in yellow and one in blue, in the TEMPLATE…

A: Mutations are changes in the sequence of DNA that arise due to a change of nucleotides, which can be…

Q: 4. Complete this table. Types of mutation: transition, transversion, missense, nonsense, silent CODE…

A: Mutation It refers to the alteration in the sequence of the DNA. It is caused by the mistakes that…

Q: 4. A recent estimate of the rate of base substitutions atSNP loci is about 1 × 10−8 per nucleotide…

A: Base substitution is the simplest type of gene mutation that involves the swapping of one nucleotide…

Q: 3. For each of the following characteristics, list all of the bases (A, B, C, or D) to which they…

A: A molecule that consists of Nitrogen and possess the chemical property of a base, is known as a…

Q: What is the mechanism of action of ultraviolet radiation in bacterial mutation?

A: Since you have asked multiple questions, we will solve the first question for you. If you want any…

Q: 1. What is mutation? Explain the random and site-directed mutagenesis methods .Which one is…

A: Since you have posted a question with multiple sub-parts, we will solve first three questions for…

Q: 1. Describe how regulation of the arginine operon would work? Is the repressor activated or…

A: Enzymes are not being expressed, even once arabinose additional to the medium. arginine is a vital…

Q: 8. Describe the possible outcome of a PCR experiment in which (a) one of the primers is…

A: Answer: Introduction: The polymerase chain reaction (PCR) technique, described by Kary Mullis in…

Q: 1.Your goal is to design a strategy to create thisfinal pDHFR plasmid for fusion protein…

A: Vectors are DNA molecules that act as transporting vehicle which carries foreign DNA into a host…

Q: 16. These mutations can occur through a mutation, which cancels the effect of the first mutation,…

A: 1. A genetic change in which a piece of one chromosome breaks off and attaches to another…

Q: Why is it that every cell needs to contain the DNA for the entire body when only a few of its genes…

A: Aside from red blood cells and cornified cells, all other cells in the human body contain nuclear…

Q: 2. Muscular dystrophy is a genetic disorder that causes progressive muscle weakness as individual…

A: Mutations are the change in the DNA sequence that it leads to several disorders. mutations can be a…

Q: I. The DNA template, 3'–CGTTACCCGAGCOCGTACGATTAGG–5', was exposed to a mutagen, resulting in the…

A: Hi, Since you have posted a question with multiple sub-parts, we are answering only first one for…

Q: How can the construct with Cas9 and gRNA sequence be removed from the plant in case it was inserted…

A: Introduction CRISPR-Cas9 is a genome editing tool that's creating a buzz in the science world. It's…

Q: 1. Methylation of DNA and acetylation of histones are inversely correlated. II. Methylation and…

A: The simplest physical as well functional component of heredity is the gene. DNA can be referred to…

Q: 8. Which of the following is NOT an example of an epigenetic mechanism? A) DNA methylation B)…

A: Since you have asked multiple questions, we will solve the first question for you. If you want any…

Q: Suggest reasons for why DNA mutations are not all phenotypic.

A: According to guidelines we have to answer the first question only. so please kindly post the…

Q: Please discuss the effect of epigenetic posttranslational modifications on cancer development…

A: Hi, this is an opinion-based question and requires an outside source, therefore, I am explaining in…

Q: 5. Describe the method of random mutagenesis using degenerate oligonucleotide primers

A: Since you have asked multiple questions, we will solve the first question for you. If you want  any…

Intelligence

Intelligence refers to the intellectual functioning that compares a person's intelligence quotient (IQ) with other people of the same age. In other words, it is the ability to understand circumstances or situations and arrive at appropriate solutions. Both animals and plants exhibit intelligence.