4. Tryptophan can also form adducts with arenediazonium ions, although the reaction is not base-catalyzed. Suggest a plausible arrow-pushing mechanism for the reaction. NO2 Trp No2 Trp NH H20 NH

27) Give the products of the reaction and provide a step-by-step mechanism for the formation of the products. O not + H₂O HCI

Draw the intermediate product and the final product for the synthesis of ethyl 3-coumarin carboxylate.

Please write the synthesis sequence to obtain the product for number 10 using the starting material the reactant provided.

If methyl phenyl ether (anisole) is treated with concentrated HBr, what products would result? By what mechanism would the reaction occur? CH₂ HB

write mechanism step by step for the reaction ?

In sugar metabolism, the enzyme phosphoglucose isomerase converts glucose-6-phosphate into fructose-6-phosphate, as shown in the reaction below. The enzyme provides a protonated Glu and a neutral Lys. Propose a three-step acid/base mechanism for this reaction. Hint: the product of the first step is an ene-diol. -203POH₂C HO.... ...OH HO OH OPO3-² -2 HO OH OH OH

Describe the reaction where two molecules of benzaldehyde will be converted to benzoin using the catalyst thiamine hydrochloride. This reaction is known as a benzoin con densation reaction.