6) What is the proposed mechanism of inheritance? a. autosomal recessive b. autosomal dominant c. sex-linked recessive d. sex-linked dominant a) Based on your answer given above, provide proper notation for two alleles for the gene under study: b) Using the alleles as you defined them, provide all known genotypic information for everyone in the pedigree. c) If III-3 and III-9 mate, what is the probability they will have an effected child? d) If IV-2 and III-9 mate, what is the probability they will have an effected child?

6) What is the proposed mechanism of inheritance? a. autosomal recessive b. autosomal dominant c. sex-linked recessive d. sex-linked dominant a) Based on your answer given above, provide proper notation for two alleles for the gene under study: b) Using the alleles as you defined them, provide all known genotypic information for everyone in the pedigree. c) If III-3 and III-9 mate, what is the probability they will have an effected child? d) If IV-2 and III-9 mate, what is the probability they will have an effected child?

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter11: Genome Alterations: Mutation And Epigenetics

Section: Chapter Questions

Problem 16QP: Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior...

See similar textbooks

Similar questions

Phenylketonuria (PKU) is a disease that results from a recessive gene.Suppose that two unaffected parents produce a child with PKU. a. What is the probability that a sperm from the father will contain the PKU allele?b. What is the probability that an egg from the mother will contain the PKU allele?c. What is the probability that their next child will have PKU?d. What is the probability that their next child will be heterozygous for the PKU gene?
Phenylketonuria (PKU) is a disease that results from a recessive gene. Suppose that two unaffected parents produce a child with PKU. a. What is the probability that a sperm from the father will contain the PKU allele? b. What is the probability that an egg from the mother will contain the PKU allele? c. What is the probability that their next child will have PKU? d. What is the probability that their next child will be heterozygous for the PKU gene?
Below is a pedigree of a human genetic disease in which solid color indicates affected individuals. Assume that the disease is caused by a gene that can have the alleles A or a. a) Based on this pedigree, what is the most likely mode of inheritance? b) What is/are the possible genotype/s of person 1? c) What is/are the possible genotype (s) of person 4 ? Explain your answers.
Rabbits may be classified as agouti, chinchilla, Himalayan, or albino according to coat color. A cross between CC h x C ch c produced 5 agouti, 3 chinchilla and 2 Himalayans. a. What are the phenotypes of the parent rabbits? Copy the genotypes then write the corresponding phenotype beside each. b. What are the genotypes of the F1s? c. What mode of inheritance is exhibited? d. If the two F1 agouti genotypes will be crossed, what percentage of theiroffspring will have the same phenotype? e. What will be the genotypes of the rabbits in (d)?
Rabbits may be classified as agouti, chinchilla, Himalayan, or albino according to coat color. A crossbetween CC^h x C^ch c produced 5 agouti, 3 chinchilla and 2 Himalayans. a. What are the phenotypes of the parent rabbits? b. What are the genotypes of the F1s? c. What mode of inheritance is exhibited? d. If the two F1 agouti genotypes will be crossed, what percentage of their offspring will have the same phenotype? e. What will be the genotypes of the rabbits in (d)?
Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior history of the disease. Consider the following pedigree (the darkly colored symbols represent affected individuals): a. Circle the individual(s) in which the mutation most likely occurred. b. Is the person who is the source of the mutation affected by retinoblastoma? Justify your answer. c. Assuming that the mutant allele is fully penetrant, what is the chance that an affected individual will have an affected child?
Using the pedigree chart attached: Above is a pedigree for colorblindness. Based on the pedigree, is the disease dominant or recessive and is it sex-linked or autosomal? Why? Furthermore, what is the probability that 18 on this chart is affected but the condition, and what is the probability that 18 is a carrier? Why? Are the probability of being a carrier and an affected individual different? Why?
In a trait that follows Mendelian rules of inheritance, what is the only way an organism can have the recessive phenotype? A. By having the homozygous recessive genotype B. By being heterozygous for that genotype C. It is not possible to get the recessive phenotype in Mendelian genetics D. If one parent is homozygous recessive for that trait, any offspring are guaranteed the recessive phenotype E. By being homozygous dominant for that genotype
A common kind of red-green blindness in humans is caused by the presence of a sex-linked recessive gene c, whose normal allele is c+. Using these genes, what are the possible genotypes and their corresponding phenotypes in males and females? Can two colorblind parents produce a normal son? (b) A normal daughter? (c) Can two normal parents produce a colorblind son? (d) a colorblind daughter?
Could the pedigree in Figure 2-31 be explained as an autosomal dominant disorder? Explain.
A young couple went to see a genetic counselor because each had a sibling with cystic fibrosis. (Cysticfibrosis is a recessive disease, and neither member ofthe couple nor any of their four parents is affected.)a. What is the probability that the female of thiscouple is a carrier?b. What are the chances that their child will havecystic fibrosis?c. What is the probability that their child will be acarrier of the cystic fibrosis disease allele?
When examining a human pedigree, what features do you look forto distinguish between X-linked recessive inheritance and autosomal recessive inheritance? How would you distinguish X-linkeddominant inheritance from autosomal dominant inheritance in ahuman pedigree?