6. Hair, primarily made of a-helical Keratin protein, grows at a rate of ~ 15 cm/year. Based on your knowledge of an a-helix (pitch and # of amino acids per turn), calculate the rate at which peptide bonds must be synthesized (bonds per second) to account for the yearly growth of a hair follicle.

1. What is the length in AA’s of the LilP protein? Assume fMet is NOT CLEAVED. 2. Write out the sequence of the polypeptide in AA: use the three letter notation, e.g. Met-Ser-Pro-

The vast majority of structures deposited in the Protein Databank (>95%) have been determined using NMR   Hard keratins (such as in the skin) are less resistant to stretch because the larger number of disulfide bonds resist deformative forces.   Structures produced by X-ray diffraction are as good as the solutions from which they are derived     they are false and I know that but explain why they are false

6. b. Draw a box around the disulfide bridge in oxytocin, if present, or write "none". 7. Mark each peptide bond in oxytocin by making the corresponding line in the structure thicker or marking it with a different color. The first one is shown for you as an example (in dark orange). 8. Number the central carbon of each amino acid in oxytocin by pointing a small arrow to it or by circling the corresponding vertex in the image. Numbers 1 and 2 indicate the central carbons of the first and second amino acids of oxytocin, and are shown for you as an example. 9. Fill out the following table, listing amino acids that make up oxytocin in order, from the N terminus to the C terminus, characterizing each amino acid by the properties of its R group (side chains), and briefly indicating the reasoning for the characterization. You may consult amino acid groupings by category in the slides (or the textbook, p.49), but you must explain the reasoning for each in your own words. CO 1 AA# Abbre- Full…