6. Suppose there is a glycolytic-like pathway carried out by an alien species that uses analogous enyzme mechanisms to convert an 8-carbon sugar (O see structure below) to two 4 carbon fragments and then to a pyruvate analog. Draw the mechanism for the conversion of 8-carbon bisphosphate (compound © below) to the two 4 carbon fragments (compounds O and ©) using the mechanism of fructose-1,6-bisphosphate aldolase (Type I) as your model. You need to include the steps for the formation of the covalent intermediate between the enzyme and the substrate. 2 3 CH2OH CH2OH CH,OH CH2OPO,2- -OH -OH -OH -OH HO- но- но- Но но HO- но- но- -OH -OH -OH -OH -OH -OH -OH- -OH ČH2OH ČH,OPO,2 ČH,OPO,2- ČH,OPO,2- 6 CH2OPO,2- CHO -OH -OH ČH2OH ČH2OPO,2 운 운

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter22: Gluconeogenesis, Glycogen Metabolism, And The Pentose Phosphate Pathway
Section: Chapter Questions
Problem 11P: Understanding the Mechanisms of Reactions Related to Transketolase The mechanistic chemistry of the...
icon
Related questions
icon
Concept explainers
Question
6. Suppose there is a glycolytic-like pathway carried out by an alien species that uses
analogous enyzme mechanisms to convert an 8-carbon sugar (O see structure below) to
two 4 carbon fragments and then to a pyruvate analog. Draw the mechanism for the
conversion of 8-carbon bisphosphate (compound © below) to the two 4 carbon fragments
(compounds 6 and ©) using the mechanism of fructose-1,6-bisphosphate aldolase (Type I)
as your model. You need to include the steps for the formation of the covalent intermediate
between the enzyme and the substrate.
2
CH2OH
CH,OH
CH2OH
CH2OPO,2-
-OH
-OH
-OH
-O-
но-
но-
но
Но
но-
но
но
HO
-OH
-OH
-OH
-O-
-OH
-OH
-OH
-O-
ČH,OH
ČH2OPO,2-
ČH,OPO,2-
CH,OPO,2
6
CH2OPO,2-
CHO
-OH
-OH
ČH2OH
ČH2OPO,2-
우 우
Transcribed Image Text:6. Suppose there is a glycolytic-like pathway carried out by an alien species that uses analogous enyzme mechanisms to convert an 8-carbon sugar (O see structure below) to two 4 carbon fragments and then to a pyruvate analog. Draw the mechanism for the conversion of 8-carbon bisphosphate (compound © below) to the two 4 carbon fragments (compounds 6 and ©) using the mechanism of fructose-1,6-bisphosphate aldolase (Type I) as your model. You need to include the steps for the formation of the covalent intermediate between the enzyme and the substrate. 2 CH2OH CH,OH CH2OH CH2OPO,2- -OH -OH -OH -O- но- но- но Но но- но но HO -OH -OH -OH -O- -OH -OH -OH -O- ČH,OH ČH2OPO,2- ČH,OPO,2- CH,OPO,2 6 CH2OPO,2- CHO -OH -OH ČH2OH ČH2OPO,2- 우 우
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 3 steps with 1 images

Blurred answer
Knowledge Booster
Metabolic pathways
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Biology: The Dynamic Science (MindTap Course List)
Biology: The Dynamic Science (MindTap Course List)
Biology
ISBN:
9781305389892
Author:
Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:
Cengage Learning
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781938168130
Author:
Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Publisher:
OpenStax College
Biology (MindTap Course List)
Biology (MindTap Course List)
Biology
ISBN:
9781337392938
Author:
Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:
Cengage Learning