A double-blind, randomized comparative experiment compared the effect of the drug lorcaserin and a placebo on weight loss in overweight adults. All subjects also underwent diet and exercise counseling. The study reported that, after one year, patients in the lorcaserin group had an average weight loss of 5.8 kilograms (kg), while those on the placebo had an average weight loss of 2.2 kg (P < 0.001). Explain to someone who knows no statistics why these results mean that there is good reason to think that lorcaserin works. Include an explanation of what P < 0.001 means.
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A double-blind, randomized comparative experiment compared the effect of the drug lorcaserin and a placebo on weight loss in overweight adults. All subjects also underwent diet and exercise counseling. The study reported that, after one year, patients in the lorcaserin group had an average weight loss of 5.8 kilograms (kg), while those on the placebo had an average weight loss of 2.2 kg (P < 0.001). Explain to someone who knows no statistics why these results mean that there is good reason to think that lorcaserin works. Include an explanation of what P < 0.001 means.
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- In its January 25, 2012, issue, the Journal of the American Medical Association reported on the effects of overconsumption of low, normal, and high protein diets on weight gain, energy expenditure, and body composition. Researchers conducted a single blind, randomized controlled trial of 25 U.S. adults. The subjects were healthy, weight-stable, male and female volunteers, aged 18 to 35 years. All subjects consumed a weight-stabilizing diet for 13 to 25 days. Afterwards, the researchers randomly assigned participants to diets containing various percentages of energy from protein: 5% (low protein), 15% (normal protein), or 25% (high protein). The subjects were not aware of the specific protein level diet to which they were assigned. On these diets the researchers overfed the participants during the last 8 weeks of their 10 to 12 week stay in the inpatient metabolic unit. The goal was to investigate the effect of overconsumption of protein on weight gain, energy expenditure, and body…To combat antibiotic resistance, the Quality Improvement Consortium recommends a throat swab to confirm strep throat before a physician prescribes antibiotics to children under age 5. Nationally, 40 percent of children under 5 who received antibiotics did not have a throat swab. The Colorado Department of Health took a random sample of 100 children under the age of 5 who received antibiotics for throat infections and found that 30 did not have a throat swab. At α = .05, is this a statistically significant reduction over last year’s national rate of 40 percent? (a-1) Choose the correct null and alternative hypotheses. H0: π ≥ .40 vs. H1: π < .40 H0: π ≤ .40 vs. H1: π > .40 H0: π = .40 vs. H1: π ≠ .40 (a-2) Calculate the critical value. (A negative value should be indicated by a minus sign. Round your answer to 3 decimal places.) Critical value (a-3) Calculate the test statistic. (A negative value should be indicated by a minus sign. Round your…To combat antibiotic resistance, the Quality Improvement Consortium recommends a throat swab to confirm strep throat before a physician prescribes antibiotics to children under age 5. Nationally, 40 percent of children under 5 who received antibiotics did not have a throat swab. The Colorado Department of Health took a random sample of 60 children under the age of 5 who received antibiotics for throat infections and found that 18 did not have a throat swab. At α = .05, is this a statistically significant reduction over last year’s national rate of 40 percent? (a-1) Calculate the critical value. (A negative value should be indicated by a minus sign. Round your answer to 3 decimal places.) Critical value _____ (a-2) Calculate the test statistic. (A negative value should be indicated by a minus sign. Round your answer to 2 decimal places.) Test statistic _____
- In randomized, double-blind clinical trials of a new vaccine, children were randomly divided into two groups. Subjects in group 1 received the new vaccine while subjects in group 2 received a control vaccine. After the second dose, 116 of 651 subjects in the experimental group (group 1) experienced fever as a side effect. After the second dose, 73 of 532 of the subjects in the control group (group 2) experienced fever as a side effect. Does the evidence suggest that a higher proportion of subjects in group 1 experienced fever as a side effect than subjects in group 2 at the α=0.10 level of significance? #1 Find the test statistic for this hypothesis test.A consumer advocacy group wanted to study whether different airline carriers differed in terms of their delayed flights. In particular, the researchers were interested in the relationship between p1, the proportion of Alpha Airlines flights that were delayed at least 15 minutes, and p2, the proportion of Beta Airlines flights that were delayed at least 15 minutes. A random sample of 1,000 Alpha flights and a separate random sample of 1,000 Beta flights found that 67 of the Alpha fights and 160 of the Beta flights were delayed at least 15 minutes. The conditions for inference were checked and verified. Does this set of samples provide strong evidence that Alpha Airlines has a smaller proportion of flights that are delayed at least 15 minutes than Beta Airlines, at the α = 0.05 significance level? Find the z-table here. A. The test statistic is z = –6.56 and the P-value ≈ 0. Since the P-value ≈ 0 < 0.05, there is not sufficient evidence that Alpha Airlines has fewer delayed…A double-blind randomized experiment compared the effects of the drug Lorcaserin and a placebo on weight loss in overweight adults. All subjects were also required to undergo diet and exercise counseling. The study involved 1000 participants where half of them would take Lorcaserin and half the placebo. The researchers found that after a year the treatment group had an average weight loss of 5.8 kg while the placebo group had an average weight loss of 3.9 carmona, kg. Based on this information researchers need to decide if Locarserin can be a possible treatment for weight loss. a. What would be a Type I error in this context? Your answer should consist of both the researchers’ decision and what the reality is. b. What would be a Type II error in this context? Your answer should consist of both the researchers’ decision and what the reality is.
- In a randomized double-blind clinical trials of a new vaccine children were randomly divided into two groups subjects in group one received the new vaccine while subjects in group 2 received a control vaccine after the second dose 112 of 690 subjects in the experimental group 1 experienced drowsiness as a side effect after the second dose 69 of 571 of the subjects in the control group 2 experienced drowsiness as a side effect does the evidence suggest that a higher proportion of subjects in group 1 experience drowsiness as a side effect than subjects in group 2 at 0.05 level of significance? Determine the null and alternative hypothesis? find the test statistic for this hypothesis test? determine the P value for this hypothesis test? do we reject or not reject the null hypothesis and why? State your conclusion?In randomized, double-blind clinical trials of a new vaccine, infants were randomly divided into two groups. Subjects in group 1 received the new vaccine while subjects in group 2 received a control vaccine. After the second dose, 126 of 387 subjects in the experimental group (group 1) experienced drowsiness as a side effect. After the second dose, 158 of 574 of the subjects in the control group (group 2) experienced drowsiness as a side effect. Does the evidence suggest that a higher proportion of subjects in group 1 experienced drowsiness as a side effect than subjects in group 2 at the α=0.01 level of significance? Verify the model requirements. Select all that apply. A. The sample size is less than 5% of the population size for each sample. B. n1p11−p1≥10 and n2p21−p2≥10 C. The samples are dependent. D. The sample size is more than 5% of the population size for each sample. E. The samples are independent. F. The data come…In a clinical trial, 17 out of 900 patients taking a prescription drug complaint of flu like symptoms. Suppose that it is known that 1.3% of the patients taking competing drugs complain of flu like symptoms. Is there sufficient evidence to conclude that more than 1.3% of the drugs user experience food like symptoms as a side effect at the 0.01 level of significance? what are the normal and alternative hypothesis?
- An experiment was conducted for better understanding of the effectiveness of a particular type of drug for reducing bad cholesterol (LDL) level. The purpose of the experiment was to determine whether different dosages used have significant different outcomes in average LDL reduction. Twenty subjects with LDL at around 250 to 300 mg/dL had participated in the study and were randomly divided into four groups. Each group was given a specific level of dosage of the drug each day for one month, with a control group that only provided with placebo. The reduction in LDL was recorded and showed in the following table. Positive number indicates reduction and negative numbers indicates increasing in DLD. Use statistical software to analyze the data and answer the following question. Control Light Dosage Level Medium Dosage Level Heavy Dosage Level 7 25 73 81 -3 17 60 71 6 22 55 79 5 21 41 60 15 12 36 85 Perform a One-way…Tardigrades, or water bears, are a type of micro-animal famous for their resilience. In examining the effects of radiation on organisms, an expert claimed that the amount of gamma radiation needed to sterilize a colony of tardigrades no longer has a mean of 900 Gy (grays). (For comparison, humans cannot withstand more than 10 Gy .) A study was conducted on a sample of 27 randomly selected tardigrade colonies, finding that the amount of gamma radiation needed to sterilize a colony had a sample mean of 907 Gy , with a sample standard deviation of 17 Gy . Assume that the population of amounts of gamma radiation needed to sterilize a colony of tardigrades is approximately normally distributed. Complete the parts below to perform a hypothesis test to see if there is enough evidence, at the 0.05 level of significance, to support the claim that μ , the mean amount of gamma radiation needed to sterilize a colony of tardigrades, is not equal to 900…Tardigrades, or water bears, are a type of micro-animal famous for their resilience. In examining the effects of radiation on organisms, an expert claimed that the amount of gamma radiation needed to sterilize a colony of tardigrades no longer has a mean of 900 Gy (grays). (For comparison, humans cannot withstand more than 10 Gy .) A study was conducted on a sample of 27 randomly selected tardigrade colonies, finding that the amount of gamma radiation needed to sterilize a colony had a sample mean of 907 Gy , with a sample standard deviation of 17 Gy . Assume that the population of amounts of gamma radiation needed to sterilize a colony of tardigrades is approximately normally distributed. Complete the parts below to perform a hypothesis test to see if there is enough evidence, at the 0.05 level of significance, to support the claim that μ , the mean amount of gamma radiation needed to sterilize a colony of tardigrades, is not equal to 900…