A new antagonist molecule has been discovered that binds to and blocks plasma membrane receptors. What effect will this antagonist have on testosterone, a steroid hormone? a. It will block testosterone from binding to its receptor. b. It will block testosterone from activating cAMP signaling. c. It will increase testosterone-mediated signaling. d. It will not affect testosterone-mediated signaling.

A new antagonist molecule has been discovered that binds to and blocks plasma membrane receptors. What effect will this antagonist have on testosterone, a steroid hormone? a. It will block testosterone from binding to its receptor. b. It will block testosterone from activating cAMP signaling. c. It will increase testosterone-mediated signaling. d. It will not affect testosterone-mediated signaling.

Biology (MindTap Course List)

11th Edition

ISBN:9781337392938

Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Chapter49: Endocrine Regulation

Section: Chapter Questions

Problem 1TYU: A cell secretes a product that diffuses through the interstitial fluid and acts on nearby cells....

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Endocrine downregulation ... a) ... occurs in target cells that respond to hormones that are present in constant amounts in the blood. b) ... leads to the increased sensitivity of the target organ to the hormone. c) ... leads to a decrease in the number of receptors in the target cell. d)... occurs in part due to increased receptor synthesis in the target cell.
A small molecule binds to a G protein, preventing itsactivation. What direct effect will this have on signalingthat involves cAMP?a. The hormone will not be able to bind to thehormone receptor.b. Adenylyl cyclase will not be activated.c. Excessive quantities of cAMP will be produced.d. The phosphorylation cascade will be initiated.
Which of the following observations can be explained by the properties of hormone receptors? a) A certain tissue can react to more than one hormone b) A certain hormone affects only a specific tissue, not all tissues c) Some tissues react very quickly to a certain hormone, other tissues take many hours to react to the same hormone
An increase in epinephrine results in: a. An increase activity of insulin. b. An increased activity of protein kinase A. c. A decreased level of cAMP. d. An increase activity of protein phosphatase.
Suppose you are studying a cell’s response to a particularhormone. You observe that the cell produces the same response to thehormone whether or not the cell is treated with a chemical that blockstranscription. What can you surmise about the hormone and its receptor?
A cell secretes a product that diffuses through the interstitial fluid and acts on nearby cells. This process is an example of (a) neuroendocrine secretion (b) autocrine signaling (c) paracrine signaling (d) classical endocrine regulation (e) peptide hormone function
What casuses a cell to be sensative to particular hormone? A. all cells are exposed to the endocrine signals so they are all sensivtive to it B.the presense of receptors for that hormone c. the shorter the distance between the source cell and the target cell, the more sensitive the target cell is to the hormone.
One such laboratory study investigated the binding of a hormone to three different receptor proteins in the cell membrane. The data collected are shown in the table below Which of the proteins demonstrate the tightest/strongest binding of the hormone? Which demonstrates the least tight binding of the hormone? What is the basis for your answer?
How does the binding of a hormone to a receptor activate a G-protein? a. It replaces bound GDP with GTP. b. It’s magic. c. It replaces bound GTP for GDP. d. A and B. e. None of the above.
Suppose that two different organs, such as the liver and heart, are sensitive to a particular hormone (such as epinephrine). The cells in both organs have identical receptors for the hormone, and hormone-receptor binding produces the same intracellular second messenger in both organs. However, the hormone produces different effects in the two organs. Explain how this can happen.
You learn that your “new” discovered hormone activates phospholipase C. Based on this, which one of the following changes is most likely to occur following hormone administration? a. Intracellular DAG levels will increase b. Cytosolic Ca concentrations will decrease c. Ca association with calmodulin will decrease d. Phosphorylation of protein tyrosine residues will increase e. None of the above
The response of a target cell to a hormone depends ona. the receptor in the target cell that binds thehormone.b. which second messengers are activated in the cell.c. the type of cell.d. all of these factors.