According to my study guide text book, the thyroid's response to hypersecretion of thyroid-stimulating hormone is metaplasia, dysplasia and/or deoplasia, but the gall bladder hypertrophies with the development of gallstones and the liver experiences hyperplaisa in response to prolonged drug intoxication. I am not understanding why these cellular adaptations occur. To me, it seems like teach organ is having to work harder, and would either hypertrophy or hyperplasia.

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