Question
Asked Nov 30, 2019
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How can I design a multi-step synthesis for the following:

alkyl bromide
OH
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alkyl bromide OH

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Expert Answer

Step 1

The final product can be prepared in the following steps:

Step 1 : Preparation of Grignard reagent

An alkyl halide (R-X) reacts with metals like magnesium (Mg) in the presence of dry ether to give Grignard reagent (R-MgX).

Here, the alkyl halide used will be cyclohexyl bromide (C6H11Br) which reacts with Mg to give the Grignard reagent, C6H11MgBr

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Bn May ether alkiyl bronnde (ayleharyl bremde grugnand edgent)

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Step 2

Step 2 : Preparation of alcohol from aldehyde and Grignard reagents

Alcohols can be prepared from aldehyde with the help of Grignard reagents.

Here, the Grignard reagent formed (C6H11MgBr) will be reacted with ethanal (CH3-CHO) to form the final product.

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`애H i. CH-C-H 2. H2O (Gragmand erqent)

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Step 3

The mechanism for this reac...

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OMBR - U3 CH--C-H OH H-O Oniny Br) OH

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