Alpha-glucosidase inhibitors are contraindicated in all of the following cases, except:A. Diabetic ketoacidosisA. Liver cirrhosisB. HypertensionC. Large abdominal herniasD. Ulcerative colitis

Essentials of Pharmacology for Health Professions
7th Edition
ISBN:9781305441620
Author:WOODROW
Publisher:WOODROW
ChapterCRE2: Comprehensive Review Exam For Part 2
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Problem 15CEP2
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Alpha-glucosidase inhibitors are contraindicated in all of the following cases, except:
A. Diabetic ketoacidosis
A. Liver cirrhosis
B. Hypertension
C. Large abdominal hernias
D. Ulcerative colitis

Expert Solution
Step 1

Alpha glucosidase inhibitors are generally used in the treatment of type-II diabetes. Alpha glucosidase inhibitors delay the absorption of the carbohydrates from small intestine and therefore they have an inhibiting effect on the postprandial blood glucose and the levels of insulin.

Step 2

The alpha glucosidase inhibitors (AGIs) are contraindicated in the patients with inflammatory bowel disease, diabetic ketoacidosis, ulcerative colitis, chronic intestinal disease, intestinal obstruction, liver cirrhosis, large abdominal hernias, and any condition that emerge by the increased gas production in the intestine.

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