Approximately 50 million SNPs have thus far beenrecorded after the characterization of thousands ofhuman genomes.a. About how many base pairs in the human genomeare identical in these thousands of people?b. Do you think that many other SNPs exist among thehuman population? If so, why haven’t they been found?c. Almost all of the SNP polymorphisms found to dateare biallelic; that is, among all the genomes in thepopulation studied to date, only two possible allelescan be found (for example, A and C). Provide arough estimate for the number of triallelic SNP locithat could be found in the same group of humans(that is, the number of loci with three differentalleles—for example, A, C, and T). At about howmany loci would all four possible nucleotides befound among the human genomes studied to date?
Approximately 50 million SNPs have thus far been
recorded after the characterization of thousands of
human genomes.
a. About how many base pairs in the human genome
are identical in these thousands of people?
b. Do you think that many other SNPs exist among the
human population? If so, why haven’t they been found?
c. Almost all of the SNP polymorphisms found to date
are biallelic; that is, among all the genomes in the
population studied to date, only two possible alleles
can be found (for example, A and C). Provide a
rough estimate for the number of triallelic SNP loci
that could be found in the same group of humans
(that is, the number of loci with three different
alleles—for example, A, C, and T). At about how
many loci would all four possible
found among the human genomes studied to date?
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