Aspirin is a weak acid with a pk, of 3.5. It is absorbed into the blood through the cells lining the stomach and the small intestine. Absorption requires passage through the plasma membrane, the rate of which is determined by the polarity of the molecule, charged and polar molecules tend to pass more slowly, whereas neutral hydrophobic molecules pass rapidly. The pH of the stomach contents is about 1.5, and the pH of the contents of the small intestine is about 6. Is the aspirin absorbed into the bloodstream from the stomach or the small intestine? Clearly justify your choice. ОН Acetylsalicylic Acid (Aspirin)

Principles of Modern Chemistry
8th Edition
ISBN:9781305079113
Author:David W. Oxtoby, H. Pat Gillis, Laurie J. Butler
Publisher:David W. Oxtoby, H. Pat Gillis, Laurie J. Butler
Chapter15: Acid–base Equilibria
Section: Chapter Questions
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Aspirin is a weak acid with a pk, of 3.5. It is absorbed into the blood through the cells lining the
stomach and the small intestine. Absorption requires passage through the plasma membrane, the
rate of which is determined by the polarity of the molecule, charged and polar molecules tend to pass
more slowly, whereas neutral hydrophobic molecules pass rapidly. The pH of the stomach contents is
about 1.5, and the pH of the contents of the small intestine is about 6. Is the aspirin absorbed into the
bloodstream from the stomach or the small intestine? Clearly justify your choice.
ОН
Acetylsalicylic Acid
(Aspirin)
Transcribed Image Text:Aspirin is a weak acid with a pk, of 3.5. It is absorbed into the blood through the cells lining the stomach and the small intestine. Absorption requires passage through the plasma membrane, the rate of which is determined by the polarity of the molecule, charged and polar molecules tend to pass more slowly, whereas neutral hydrophobic molecules pass rapidly. The pH of the stomach contents is about 1.5, and the pH of the contents of the small intestine is about 6. Is the aspirin absorbed into the bloodstream from the stomach or the small intestine? Clearly justify your choice. ОН Acetylsalicylic Acid (Aspirin)
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