close search
Hit Return to see all results

Bacillus Anthracis virulence factors, pathogenesis, transmission and epidemiology,  treatment


Bacillus Anthracis virulence factors, pathogenesis, transmission and epidemiology,  treatment

Step 1

Bacillus anthracis is an endospore-forming gram-positive bacterium. It is a rod-shaped bacterium with 1.0-1.2 micrometer width and 3-5 micrometer length. This bacterium is responsible for the infection, anthrax. Anthrax is a very common livestock disease, which is generally seen in humans. It can easily grow in normal nutrient medium and in aerobic or anaerobic conditions.

Step 2

Bacillus anthracis contains three types of primary virulence factors, an extracellular poly-D-glutamate capsule (D-PGA capsule), edema toxin (ET), and lethal toxin (LT). these factors are induced by the presence of carbon dioxide, physiological temperature, and the presence of bicarbonate in mammalian hosts. D-PGA capsule is formed by the enzymes, CapA, CapB, and CapC, which are encoded by the gene capBCAD. ET and LT toxins are composed of enzymatic A-components edema factor (EF) or lethal factor (LF), respectively.

Step 3

The pathogenic process of Bacillus anthracis is done by using capsule and toxins, which contains different kind of proteins. The combination of edema toxin and lethal toxin can result in induction of severe cases of the diseases. The edema toxin contains an edema factor and the protective antigen, and...

Want to see the full answer?

See Solution

Check out a sample Q&A here.

Want to see this answer and more?

Our solutions are written by experts, many with advanced degrees, and available 24/7

See Solution
Tagged in




Related Biology Q&A

Find answers to questions asked by student like you

Show more Q&A add

Q: A plasmid provides its host with kanamycin resistance. What will happen to the plasmid if you cultur...

A: Plasmids are defined as extrachromosomal circular genetic elements that are capable of self-replicat...


Q: What functions as heat insulator and located in the subcutaneous layer below the skin?

A: The subcutaneous layer or superficial fascia, also known as the hypodermis, is a layer that is prese...


Q: What body tissue is composed primarily of fluid and transports nutrients and respiratory gases throu...

A: There are four basic types of animal tissues such as muscle tissue, epithelial tissue, connective ti...


Q: L Give Up? Resources Hint Match the functions to the organ system with which each is associated. Ner...

A: An organ is formed of two or more tissues working to perform specific functions. An organ system con...


Q: Are plants capable of surviving global warming ?

A: Capability of plants to survive global warming largely depends on the genetic variability of the pla...


Q: What are the possible sources of contamination that may result during the streak plate procedure?

A: The streak plate procedure is used to isolate microbial colonies in pure form. During the procedure,...


Q: What is an endospore and its function?

A: The bacteria is the unicellular prokaryotic organism that maintains a definite shape since it contai...


Q: Some DNA polymerases have proofreading activities. After a nucleotide is added to a growing nucleic ...

A:   Ribosomes also have similar proofreading activities during translation.  The proofreading activity...


Q: 1. If you block calcium channels on an axon, which will not occur? A) exocytosis of neurotransmitter...

A: A calcium channel is an ion channel that is selectively permeable to calcium ions. It is also called...

Sorry about that. What wasn’t helpful?