Being heterozygous for Sickle Cell allows a person to be resistant to malaria but comes at the cost of long term health problems like cardiac arrest and stroke. Being homozygous for Sickle Cell results in reduced life span. Which of the following is the least likely reason this trait persists in the population? the trait is recessive the trait does not harm carriers the trait generally has the most impact on patients post reproductive maturity the benefit is greater than the cost
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- The trait of blood pressure in humans has a frequency distributionthat is similar to a normal distribution. The following graph showsthe ranges of blood pressures for a selected population of people.The red line depicts the frequency distribution of the systolic pressuresfor the entire population. Several individuals with high bloodpressure were identified, and the blood pressures of their relativeswere determined. This frequency distribution is depicted with a blueline. (Note: The blue line does not include the people who wereidentified with high blood pressure; it includes only their relatives.) What do these data suggest with regard to a genetic basis for highblood pressure? What statistical approach could you use to determinethe heritability for this trait?Among the most prevalent pathologies that afflicthuman beings is heart disease, which can have a severeimpact on quality of life and can even result in prematuredeath. While heart disease mostly afflicts those who areolder, 1% or 2% of people in their 30s, and even in their20s, suffer from this disease. Genetic and environmentalcomponents of this disease exist. What strategy mightyou use to choose families to participate in a GWAS ofheart disease–causing genes? Explain your reasoning.The term Asian American refers to people of Asian descent who trace their roots to more than 20 different countries in Asia, including Cambodia, China, India, Japan, Korea, Malaysia, Pakistan, Philippines, Thailand and Vietnam. Given below are the leading causes of death for Asian Americans and other minority groups in the U.S. With this data, compare the leading causes of deaths of Filipinos and answer the following questions. 1. Is race/ethnicity a significant factor affecting these populations’ mortality? Howso? 2. What other considerations should be included in the discussion of the leadingcauses of deaths for these populations?
- Which of the following would not be consistent with the ideathat a disorder has a genetic component?a. The disorder is more likely to occur among an affectedperson’s relatives than in the general population.b. The disorder can spread to individuals sharing similarenvironments.c. The disorder tends to develop at a characteristic age.d. A correlation is observed between the disorder and amutant gene.Cystic fibrosis is a homozygous recessive condition that affects 1 in 10,000 of the Hispanic populationin the United States. Calculate the frequency of the dominant allele, the frequency of the recessiveallele, and the percentage of heterozygous individuals (carriers) in the Hispanic population.Frequency of thedominant alleleFrequency of therecessive allele% homozygous dominant% homozygous recessive% heterozygousA population of frogs consists of 1000 individuals of which 400 are red. Red is recessive to Green. What is the frequency of the dominant allele and the recessive allele in this population? What is the frequency of individuals with homozygous dominant phenotypes? Please answer and show all work, thank you!! :)
- In a large, randomly mating population, the frequency of the allele (s)for sickle-cell hemoglobin is 0.028. The results of studies have shownthat people with the following genotypes at the beta-chain locus producethe following average numbers of offspring:Genotype Average numberof offspring producedSS 5Ss 6ss 0a. What will the frequency of the sickle-cell allele (s) be in the nextgeneration?b. What will the frequency of the sickle-cell allele be at equilibrium?The prevalence (frequency) of sickle-cell disease in Canada is quite low, affecting 1/3800 individuals. However, in some African populations 1/25 individuals are affected by sickle-cell disease. The difference in frequency of this allele within the differing populations has to do with the adaptation pressures that exist in the different environments. Individuals with the heterozygous genotype have a survival advantage in environments where the disease malaria is prevalent as the presence of this mutant allele leads to resistance to malaria. Therefore, the sickle-cell disease tends to be more frequent in environments where the malaria parasite is most common. Question: Explain why the sickle-cell disease remains frequent in some populations while it exists in very low frequency in other populations.A geneticist is interested in whether asthma is caused by a mutation in the DS112 gene.The geneticist collects DNA from 120 people with asthma and 100 healthy people, andshe sequences the DNA. She finds that 35 of the people with asthma and none of thehealthy people have a mutation in the DS112 gene. What is the population in this study?a. The 120 people with asthmab. The 100 healthy peoplec. The 35 people with a mutation in the DS112 gened. All people with asthma
- The classical twin study is established as the definitive study design for investigating the relative importance of genetic and environmental factors to traits and diseases in human population. Monozygotic (identical) twins share all of their genes, while Dizygotic(fraternal) twins share only about 50 percent of them, the same as non-twin siblings. If a researcher compares the similarity between sets of identical twins to that of fraternal twins for a particular trait, then any excess likeness between the identical twins should be due to genes rather than environment. Write an information leaflet evaluating the benefits and dilemmas in the use of human twin studies to investigate the causes of variation.Identify each of the following as an example of allele, genotype, and/or phenotype frequency: A. Approximately 1 in 2500 people of Northern European descent is born with cystic fibrosis. B. The percentage of carriers of the sickle cell allele in West Africa is approximately 13%. C. The number of new mutations for achondroplasia, a genetic disorder, is approximately 5 × 10–5.Tay-Sachs disease is a recessive genetic disease. Individuals with this disease rarely survive past the age of four. In the general population, approximately 1 person in 300 carries the allele for this disease. However, in some populations, including the Irish Americans, the Ashkenazi Jews, and the Cajuns from Louisiana, the proportion of Tay-Sachs carriers is much higher (1 in 27 to 1 in 50) than in other populations. Such high frequency of an otherwise rare allele is expected when Question 24 options: populations experienced disruptive selection populations were founded by a small number of settlers the allele is advantageous at the heterozygous state populations have higher than average mutation rates populations experienced stabilizing selection